YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: SPT5
Organism: Saccharomyces cerevisiae
Length: 1063 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPT5.

Description E-value Query
Range
Subject
Range
SPT5 - Protein involved in regulating Pol I and Pol II transcription and pre-mRNA processing; forms a compl...
SPT5_YEAST - Transcription elongation factor SPT5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SPT...
0.0 [1..1063] [1..1063]
gi|2723380 - gi|2723380|dbj|BAA24075.1| DSIF p160 [Homo sapiens]
0.0 [107..1062] [2..971]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [107..1062] [2..965]
SPT5H_DANRE - Transcription elongation factor SPT5 OS=Danio rerio GN=supt5h PE=1 SV=1
0.0 [107..1060] [2..967]
SPT52_ARATH - Putative transcription elongation factor SPT5 homolog 2 OS=Arabidopsis thaliana GN=At2g34210 PE=2 SV...
0.0 [123..1025] [5..886]
gi|17861616 - gi|17861616|gb|AAL39285.1| GH15359p [Drosophila melanogaster]
0.0 [490..917] [1..427]
gi|19074993, gi|... - gi|19074993|ref|NP_586499.1| similarity to putative transcription factor SPT5 [Encephalitozoon cunic...
gi|19074993 - gi|19074993|ref|NP_586499.1| similarity to putative transcription factor SPT5 [Encephalitozoon cunic...
4.0E-87 [210..636] [11..359]
gi|3236370 - gi|3236370|gb|AAC23667.1| type VI collagen alpha 3 subunit [Mus musculus]
6.0E-70 [715..1030] [1423..1761]

Back

Predicted Domain #1
Region A:
Residues: [1-232]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDNSDTNVS MQDHDQQFAD PVVVPQSTDT KDENTSDKDT VDSGNVTTTE STERAESTSN  60
   61 IPPLDGEEKE AKSEPQQPED NAETAATEQV SSSNGPATDD AQATLNTDSS EANEIVKKEE 120
  121 GSDERKRPRE EDTKNSDGDT KDEGDNKDED DDEDDDDDDD DEDDDDEAPT KRRRQERNRF 180
  181 LDIEAEVSDD EDEDEDEEDS ELVREGFITH GDDEDDEASA PGARRDDRLH RQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [233-314]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDQDLNKTSE EDAQRLAKEL RERYGRSSSK QYRAAAQDGY VPQRFLLPSV DTATIWGVRC  60
   61 RPGKEKELIR KLLKKKFNLD RA

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 13.366532
Match: PF03439
Description: Supt5 repeat

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [315-381]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKKKLKILS IFQRDNYTGR IYIEAPKQSV IEKFCNGVPD IYISQKLLIP VQELPLLLKP  60
   61 NKSDDVA

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 15.09691
Match: PF03439
Description: Supt5 repeat

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [382-440]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEEGSYVRIK RGIYKGDLAM VDQISENNLE VMLKIVPRLD YGKFDEIDPT TQQRKSRRP

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 5.200659
Match: PF00467
Description: KOW motif

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.639 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.636 N/A N/A b.55.1 PH domain-like
View Download 0.578 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.572 N/A N/A d.87.1 FAD/NAD-linked reductases, dimerisation (C-terminal) domain
View Download 0.511 N/A N/A d.58.49 YajQ-like

Predicted Domain #5
Region A:
Residues: [441-531]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TFAHRAPPQL FNPTMALRLD QANLYKRDDR HFTYKNEDYI DGYLYKSFRI QHVETKNIQP  60
   61 TVEELARFGS KEGAVDLTSV SQSIKKAQAA K

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.636 b.55.1 PH domain-like
View Download 0.639 d.58.7 RNA-binding domain, RBD
View Download 0.511 d.58.49 YajQ-like
View Download 0.572 d.87.1 FAD/NAD-linked reductases, dimerisation (C-terminal) domain
View Download 0.471 d.129.1 TATA-box binding protein-like
View Download 0.368 a.134.1 Fungal elicitin
View Download 0.359 b.84.2 Rudiment single hybrid motif
View Download 0.330 g.52.1 Inhibitor of apoptosis (IAP) repeat
View Download 0.321 d.129.1 TATA-box binding protein-like
View Download 0.295 b.114.1 N-utilization substance G protein NusG, insert domain
View Download 0.271 a.77.1 DEATH domain
View Download 0.243 d.58.3 Protease propeptides/inhibitors
View Download 0.236 b.61.3 D-aminopeptidase, middle and C-terminal domains
View Download 0.227 d.198.1 Type III secretory system chaperone
View Download 0.204 c.30.1 PreATP-grasp domain

Predicted Domain #6
Region A:
Residues: [532-570]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTFQPGDRIE VLNGEQRGSK GIVTRTTKDI ATIKLNGFT

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 2.744727
Match: PF00467
Description: KOW motif

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [571-617]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPLEFPISTL RKIFEPGDHV TVINGEHQGD AGLVLMVEQG QVTFMST

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 4.0
Match: PF00467
Description: KOW motif

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [618-794]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QTSREVTITA NNLSKSIDTT ATSSEYALHD IVELSAKNVA CIIQAGHDIF KVIDETGKVS  60
   61 TITKGSILSK INTARARVSS VDANGNEIKI GDTIVEKVGS RREGQVLYIQ TQQIFVVSKK 120
  121 IVENAGVFVV NPSNVEAVAS KDNMLSNKMD LSKMNPEIIS KMGPPSSKTF QQPIQSR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [795-842]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGREVALGKT VRIRSAGYKG QLGIVKDVNG DKATVELHSK NKHITIDK

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 5.0
Match: PF00467
Description: KOW motif

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #10
Region A:
Residues: [843-908]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HKLTYYNREG GEGITYDELV NRRGRVPQAR MGPSYVSAPR NMATGGIAAG AAATSSGLSG  60
   61 GMTPGW

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.287 a.4.1 Homeodomain-like
View Download 0.301 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.302 a.28.1 ACP-like

Predicted Domain #11
Region A:
Residues: [909-1063]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSFDGGKTPA VNAHGGSGGG GVSSWGGAST WGGQGNGGAS AWGGAGGGAS AWGGQGTGAT  60
   61 STWGGASAWG NKSSWGGAST WASGGESNGA MSTWGGTGDR SAYGGASTWG GNNNNKSTRD 120
  121 GGASAWGNQD DGNRSAWNNQ GNKSNYGGNS TWGGH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.69897
Match: 1deqA_
Description: Fibrinogen
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle