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View Structure Prediction Details

Protein: YAP1
Organism: Saccharomyces cerevisiae
Length: 650 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YAP1.

Description E-value Query
Range
Subject
Range
gi|4798 - gi|4798|emb|CAA41536.1| transcriptional activator protein [Saccharomyces cerevisiae]
0.0 [1..650] [1..650]
AP1_KLULA - AP-1-like transcription factor OS=Kluyveromyces lactis GN=YAP1 PE=3 SV=1
AP1_KLULA - AP-1-like transcription factor OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NB...
0.0 [1..649] [1..582]
gi|4100263 - gi|4100263|gb|AAD00802.1| Cap1 [Candida albicans]
gi|46443503, gi|... - gi|68468526|ref|XP_721582.1| hypothetical protein CaO19.9191 [Candida albicans SC5314], gi|46443503|...
1.0E-93 [56..647] [32..495]
gi|16945426 - gi|16945426|emb|CAB91681.2| related to AP-1-like transcription factor [Neurospora crassa]
gi|157071403, gi... - gi|164426604|ref|XP_957544.2| hypothetical protein NCU03905 [Neurospora crassa OR74A], gi|157071403|...
1.0E-75 [391..650] [284..554]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
3.0E-75 [391..650] [284..546]

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Predicted Domain #1
Region A:
Residues: [1-187]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVSTAKRSL DVVSPGSLAE FEGSKSRHDE IENEHRRTGT RDGEDSEQPK KKGSKTSKKQ  60
   61 DLDPETKQKR TAQNRAAQRA FRERKERKMK ELEKKVQSLE SIQQQNEVEA TFLRDQLITL 120
  121 VNELKKYRPE TRNDSKVLEY LARRDPNLHF SKNNVNHSNS EPIDTPNDDI QENVKQKMNF 180
  181 TFQYPLD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 62.67837
Match: 1gd2E_
Description: PAP1
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [188-325]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDNDNDNSKN VGKQLPSPND PSHSAPMPIN QTQKKLSDAT DSSSATLDSL SNSNDVLNNT  60
   61 PNSSTSMDWL DNVIYTNRFV SGDDGSNSKT KNLDSNMFSN DFNFENQFDE QVSEFCSKMN 120
  121 QVCGTRQCPI PKKPISAL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.442 0.913 response to oxidative stress c.47.1 Thioredoxin-like

Predicted Domain #3
Region A:
Residues: [326-650]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DKEVFASSSI LSSNSPALTN TWESHSNITD NTPANVIATD ATKYENSFSG FGRLGFDMSA  60
   61 NHYVVNDNST GSTDSTGSTG NKNKKNNNNS DDVLPFISES PFDMNQVTNF FSPGSTGIGN 120
  121 NAASNTNPSL LQSSKEDIPF INANLAFPDD NSTNIQLQPF SESQSQNKFD YDMFFRDSSK 180
  181 EGNNLFGEFL EDDDDDKKAA NMSDDESSLI KNQLINEEPE LPKQYLQSVP GNESEISQKN 240
  241 GSSLQNADKI NNGNDNDNDN DVVPSKEGSL LRCSEIWDRI TTHPKYSDID VDGLCSELMA 300
  301 KAKCSERGVV INAEDVQLAL NKHMN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [350-518]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HSNITDNTPA NVIATDATKY ENSFSGFGRL GFDMSANHYV VNDNSTGSTD STGSTGNKNK  60
   61 KNNNNSDDVL PFISESPFDM NQVTNFFSPG STGIGNNAAS NTNPSLLQSS KEDIPFINAN 120
  121 LAFPDDNSTN IQLQPFSESQ SQNKFDYDMF FRDSSKEGNN LFGEFLEDD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [519-650]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDDKKAANMS DDESSLIKNQ LINEEPELPK QYLQSVPGNE SEISQKNGSS LQNADKINNG  60
   61 NDNDNDNDVV PSKEGSLLRC SEIWDRITTH PKYSDIDVDG LCSELMAKAK CSERGVVINA 120
  121 EDVQLALNKH MN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.30103
Match: 1sseB
Description: Solution structure of the oxidized form of the Yap1 redox domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle