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View Structure Prediction Details

Protein: UTP21
Organism: Saccharomyces cerevisiae
Length: 939 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UTP21.

Description E-value Query
Range
Subject
Range
gi|148658115, gi... - gi|148658115|ref|YP_001278320.1| NB-ARC domain-containing protein [Roseiflexus sp. RS-1], gi|1485702...
755.0 [0..2] [788..756]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
713.0 [0..19] [713..859]
gi|186464325, gi... - gi|23128981|ref|ZP_00110817.1| COG2319: FOG: WD40 repeat [Nostoc punctiforme PCC 73102], gi|18668187...
713.0 [0..13] [657..1161]
gi|75701503, gi|... - gi|75907778|ref|YP_322074.1| ribosome assembly protein 4 (RSA4) [Anabaena variabilis ATCC 29413], gi...
661.0 [0..2] [622..1063]
gi|48893630, gi|... - gi|71673807|ref|ZP_00671555.1| TPR repeat:G-protein beta WD-40 repeat:YD repeat [Trichodesmium eryth...
660.0 [0..7] [654..937]

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Predicted Domain #1
Region A:
Residues: [1-315]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIDLKKRKV EEDVRSRGKN SKIFSPFRII GNVSNGVPFA TGTLGSTFYI VTCVGKTFQI  60
   61 YDANTLHLLF VSEKETPSSI VALSAHFHYV YAAYENKVGI YKRGIEEHLL ELETDANVEH 120
  121 LCIFGDYLCA STDDNSIFIY KKSDPQDKYP SEFYTKLTVT EIQGGEIVSL QHLATYLNKL 180
  181 TVVTKSNVLL FNVRTGKLVF TSNEFPDQIT TAEPAPVLDI IALGTVTGEV IMFNMRKGKR 240
  241 IRTIKIPQSR ISSLSFRTDG SSHLSVGTSS GDLIFYDLDR RSRIHVLKNI HRESYGGVTQ 300
  301 ATFLNGQPII VTSGG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 127.69897
Match: 1gg2B
Description: beta1-subunit of the signal-transducing G protein heterotrimer
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [316-657]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DNSLKEYVFD PSLSQGSGDV VVQPPRYLRS RGGHSQPPSY IAFADSQSHF MLSASKDRSL  60
   61 WSFSLRKDAQ SQEMSQRLHK KQDGGRVGGS TIKSKFPEIV ALAIENARIG EWENIITAHK 120
  121 DEKFARTWDM RNKRVGRWTF DTTDDGFVKS VAMSQCGNFG FIGSSNGSIT IYNMQSGILR 180
  181 KKYKLHKRAV TGISLDGMNR KMVSCGLDGI VGFYDFNKST LLGKLKLDAP ITAMVYHRSS 240
  241 DLFALALDDL SIVVIDAVTQ RVVRQLWGHS NRITAFDFSP EGRWIVSASL DSTIRTWDLP 300
  301 TGGCIDGIIV DNVATNVKFS PNGDLLATTH VTGNGICIWT NR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 110.9794
Match: 1gxrA
Description: Groucho/tle1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [658-746]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AQFKTVSTRT IDESEFARMA LPSTSVRGND SMLSGALESN GGEDLNDIDF NTYTSLEQID  60
   61 KELLTLSIGP RSKMNTLLHL DVIRKRSKP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 135.54902
Match: 1erjA
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [747-939]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KEAPKKSEKL PFFLQLSGEK VGDEASVREG IAHETPEEIH RRDQEAQKKL DAEEQMNKFK  60
   61 VTGRLGFESH FTKQLREGSQ SKDYSSLLAT LINFSPAAVD LEIRSLNSFE PFDEIVWFID 120
  121 ALTQGLKSNK NFELYETFMS LLFKAHGDVI HANNKNQDIA SALQNWEDVH KKEDRLDDLV 180
  181 KFCMGVAAFV TTA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.820 N/A N/A a.118.8 TPR-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle