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View Structure Prediction Details

Protein: SKI2
Organism: Saccharomyces cerevisiae
Length: 1287 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SKI2.

Description E-value Query
Range
Subject
Range
gi|410320 - gi|410320|gb|AAA35049.1| antiviral protein [Saccharomyces cerevisiae]
1308.0 [0..1] [1287..1]
SKIV2L - superkiller viralicidic activity 2-like (S. cerevisiae)
1046.0 [0..59] [1286..65]
gi|114606536 - gi|114606536|ref|XP_001160927.1| PREDICTED: superkiller viralicidic activity 2-like homolog isoform ...
1027.0 [0..59] [1286..65]

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Predicted Domain #1
Region A:
Residues: [1-170]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEGFSSSSI QELYQSLKEI TNNADVELFE DRITKLDFES TDEPKHANDI IKDRFLRPSN  60
   61 ALPWSLLDMV QDVPHTSSPE DCSGKLDYKE LLKVPDPINR TSYQFKRTGL EGKISGYKEE 120
  121 VDLKEVANAN ASNSLSITRS INHNQNSVRG STAQLPFTPG GIPMKSVKTD 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [171-274]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEQNGSSTMA NATKLLHKDG QGLFDIPEGM NRGIKPMDSP AENEDQNGQF KELKQLNEID  60
   61 NELDIRIEAN EAKLKEEEKS AKSISEEIME EATEETTADN ADDA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [275-667]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EIDELLPIGI DFGRTKPVSK SVPVKKEWAH VVDLNHKIEN FDELIPNPAR SWPFELDTFQ  60
   61 KEAVYHLEQG DSVFVAAHTS AGKTVVAEYA IAMAHRNMTK TIYTSPIKAL SNQKFRDFKE 120
  121 TFDDVNIGLI TGDVQINPDA NCLIMTTEIL RSMLYRGADL IRDVEFVIFD EVHYVNDQDR 180
  181 GVVWEEVIIM LPQHVKFILL SATVPNTYEF ANWIGRTKQK NIYVISTPKR PVPLEINIWA 240
  241 KKELIPVINQ NSEFLEANFR KHKEILNGES AKGAPSKTDN GRGGSTARGG RGGSNTRDGR 300
  301 GGRGNSTRGG ANRGGSRGAG AIGSNKRKFF TQDGPSKKTW PEIVNYLRKR ELLPMVVFVF 360
  361 SKKRCEEYAD WLEGINFCNN KEKSQIHMFI EKS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 96.522879
Match: 1fuuA
Description: Initiation factor 4a
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [668-891]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ITRLKKEDRD LPQILKTRSL LERGIAVHHG GLLPIVKELI EILFSKGFIK VLFATETFAM  60
   61 GLNLPTRTVI FSSIRKHDGN GLRELTPGEF TQMAGRAGRR GLDSTGTVIV MAYNSPLSIA 120
  121 TFKEVTMGVP TRLQSQFRLT YNMILNLLRI EALRVEEMIK YSFSENAKET LQPEHEKQIK 180
  181 VLQEELQTIE YKSCEICDND IEKFLELMLA YKEATVNLMQ EMVK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.0
Match: 1c4oA
Description: Nucleotide excision repair enzyme UvrB
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [892-964]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPSILHILKE GRLVAFRDPN DCLKLGFVFK VSLKDAVCVI MTFTKPYKLP NGEPNHLIYF  60
   61 PKADGYRRRN FPK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.845 d.58.7 RNA-binding domain, RBD

Predicted Domain #6
Region A:
Residues: [965-1287]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FQKTDFYMEE VPVTAIEVIT KRKFAAPLGK VIKKDVAALN EFNAETNNIL DGKTLKEAIN  60
   61 IEKQGLKIHQ ILLDRTNIRD EIFKLKSIKC PNLSQHIVPK FKAHVIKKKI EELYHLMSDQ 120
  121 NLSLLPDYEK RLAVLKDTEF IDQNHNVLLK GRVACEINSG YELVLTELIL DNFLGSFEPE 180
  181 EIVALLSVFV YEGKTREEEP PIVTPRLAKG KQRIEEIYKK MLCVFNTHQI PLTQDEAEFL 240
  241 DRKRFAMMNV VYEWARGLSF KEIMEMSPEA EGTVVRVITW LDEICREVKT ASIIIGNSTL 300
  301 HMKMSRAQEL IKRDIVFAAS LYL

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 7.51
Match:
Description: No description for 1n1bA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle