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View Structure Prediction Details

Protein: AFG2
Organism: Saccharomyces cerevisiae
Length: 780 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AFG2.

Description E-value Query
Range
Subject
Range
Y1297_ARCFU - Cell division cycle protein 48 homolog AF_1297 OS=Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 ...
Y1297_ARCFU, YC9... - (O28972) Cell division cycle protein 48 homolog AF1297, Cell division cycle protein 48 homolog AF_12...
0.0 [33..778] [10..730]
CDC48_SOYBN - Cell division cycle protein 48 homolog OS=Glycine max GN=CDC48 PE=2 SV=1
0.0 [1..779] [1..770]
CD48E_ARATH - Cell division control protein 48 homolog E OS=Arabidopsis thaliana GN=CDC48E PE=1 SV=2
0.0 [1..779] [1..769]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [11..779] [44..802]
gi|3257095, gi|1... - gi|3257095|dbj|BAA29778.1| 840aa long hypothetical cell division control protein (transitional endop...
gi|7435754 - pir||H71114 probable cell division control protein (transitional endoplasmic reticulum ATPase) - Pyr...
0.0 [27..780] [8..827]
gi|18977335, gi|... - gi|18977335|ref|NP_578692.1| cell division protein CDC48 [Pyrococcus furiosus DSM 3638], gi|18893012...
0.0 [27..780] [8..824]
CDC48_CAPAN - Cell division cycle protein 48 homolog OS=Capsicum annuum GN=CAFP PE=2 SV=1
0.0 [1..779] [1..768]
TERA_RAT - Transitional endoplasmic reticulum ATPase OS=Rattus norvegicus GN=Vcp PE=1 SV=3
0.0 [7..779] [3..765]

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Predicted Domain #1
Region A:
Residues: [1-120]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPKSSSSGS KKKSSASSNS ADAKASKFKL PAEFITRPHP SKDHGKETCT AYIHPNVLSS  60
   61 LEINPGSFCT VGKIGENGIL VIARAGDEEV HPVNVITLST TIRSVGNLIL GDRLELKKAQ 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 766.9897
Match: 1e32A_
Description: Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [121-241]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VQPPYATKVT VGSLQGYNIL ECMEEKVIQK LLDDSGVIMP GMIFQNLKTK AGDESIDVVI  60
   61 TDASDDSLPD VSQLDLNMDD MYGGLDNLFY LSPPFIFRKG STHITFSKET QANRKYNLPE 120
  121 P

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 766.9897
Match: 1e32A_
Description: Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [242-413]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSYAAVGGLD KEIESLKSAI EIPLHQPTLF SSFGVSPPRG ILLHGPPGTG KTMLLRVVAN  60
   61 TSNAHVLTIN GPSIVSKYLG ETEAALRDIF NEARKYQPSI IFIDEIDSIA PNRANDDSGE 120
  121 VESRVVATLL TLMDGMGAAG KVVVIAATNR PNSVDPALRR PGRFDQEVEI GI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 766.9897
Match: 1e32A_
Description: Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [414-491]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDVDARFDIL TKQFSRMSSD RHVLDSEAIK YIASKTHGYV GADLTALCRE SVMKTIQRGL  60
   61 GTDANIDKFS LKVTLKDV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 766.9897
Match: 1e32A_
Description: Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [492-667]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESAMVDIRPS AMREIFLEMP KVYWSDIGGQ EELKTKMKEM IQLPLEASET FARLGISAPK  60
   61 GVLLYGPPGC SKTLTAKALA TESGINFLAV KGPEIFNKYV GESERAIREI FRKARSAAPS 120
  121 IIFFDEIDAL SPDRDGSSTS AANHVLTSLL NEIDGVEELK GVVIVAATNR PDEIDA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 71.045757
Match: 1d2nA_
Description: Hexamerization domain of N-ethylmalemide-sensitive fusion (NSF) protein
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [668-780]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ALLRPGRLDR HIYVGPPDVN ARLEILKKCT KKFNTEESGV DLHELADRTE GYSGAEVVLL  60
   61 CQEAGLAAIM EDLDVAKVEL RHFEKAFKGI ARGITPEMLS YYEEFALRSG SSS

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.9
Match: 1iy2A
Description: AAA domain of cell division protein FtsH
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle