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View Structure Prediction Details

Protein: IKI3
Organism: Saccharomyces cerevisiae
Length: 1349 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IKI3.

Description E-value Query
Range
Subject
Range
gi|114626066, gi... - gi|114626068|ref|XP_001143066.1| PREDICTED: inhibitor of kappa light polypeptide gene enhancer in B-...
1184.0 [0..51] [1325..23]
gi|12002688 - gi|12002688|gb|AAG43369.1|AF153419_1 IkappaBkinase complex-associated protein [Homo sapiens]
1180.0 [0..51] [1325..23]
ELP1_RAT - Elongator complex protein 1 OS=Rattus norvegicus GN=Ikbkap PE=2 SV=1
1168.0 [0..51] [1325..23]
gi|27734086, gi|... - gi|27734086|ref|NP_080355.1| inhibitor of kappa light polypeptide enhancer in B-cells, kinase comple...
1165.0 [0..51] [1325..23]

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Predicted Domain #1
Region A:
Residues: [1-548]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVEHDKSGSK RQELRSNMRN LITLNKGKFK PTASTAEGDE DDLSFTLLDS VFDTLSDSIT  60
   61 CVLGSTDIGA IEVQQFMKDG SRNVLASFNI QTFDDKLLSF VHFADINQLV FVFEQGDIIT 120
  121 ATYDPVSLDP AETLIEIMGT IDNGIAAAQW SYDEETLAMV TKDRNVVVLS KLFEPISEYH 180
  181 LEVDDLKISK HVTVGWGKKE TQFRGKGARA MEREALASLK ASGLVGNQLR DPTMPYMVDT 240
  241 GDVTALDSHE ITISWRGDCD YFAVSSVEEV PDEDDETKSI KRRAFRVFSR EGQLDSASEP 300
  301 VTGMEHQLSW KPQGSLIASI QRKTDLGEED SVDVIFFERN GLRHGEFDTR LPLDEKVESV 360
  361 CWNSNSEALA VVLANRIQLW TSKNYHWYLK QELYASDISY VKWHPEKDFT LMFSDAGFIN 420
  421 IVDFAYKMAQ GPTLEPFDNG TSLVVDGRTV NITPLALANV PPPMYYRDFE TPGNVLDVAC 480
  481 SFSNEIYAAI NKDVLIFAAV PSIEEMKKGK HPSIVCEFPK SEFTSEVDSL RQVAFINDSI 540
  541 VGVLLDTD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 67.69897
Match: 1nr0A
Description: Actin interacting protein 1
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [549-629]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLSRIALLDI QDITQPTLIT IVEVYDKIVL LRSDFDYNHL VYETRDGTVC QLDAEGQLME  60
   61 ITKFPQLVRD FRVKRVHNTS A

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [630-1188]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDDDNWSAES SELVAFGITN NGKLFANQVL LASAVTSLEI TDSFLLFTTA QHNLQFVHLN  60
   61 STDFKPLPLV EEGVEDERVR AIERGSILVS VIPSKSSVVL QATRGNLETI YPRIMVLAEV 120
  121 RKNIMAKRYK EAFIVCRTHR INLDILHDYA PELFIENLEV FINQIGRVDY LNLFISCLSE 180
  181 DDVTKTKYKE TLYSGISKSF GMEPAPLTEM QIYMKKKMFD PKTSKVNKIC DAVLNVLLSN 240
  241 PEYKKKYLQT IITAYASQNP QNLSAALKLI SELENSEEKD SCVTYLCFLQ DVNVVYKSAL 300
  301 SLYDVSLALL VAQKSQMDPR EYLPFLQELQ DNEPLRRKFL IDDYLGNYEK ALEHLSEIDK 360
  361 DGNVSEEVID YVESHDLYKH GLALYRYDSE KQNVIYNIYA KHLSSNQMYT DAAVAYEMLG 420
  421 KLKEAMGAYQ SAKRWREAMS IAVQKFPEEV ESVAEELISS LTFEHRYVDA ADIQLEYLDN 480
  481 VKEAVALYCK AYRYDIASLV AIKAKKDELL EEVVDPGLGE GFGIIAELLA DCKGQINSQL 540
  541 RRLRELRAKK EENPYAFYG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.25
Match: 2gw1A
Description: No description for 2gw1A was found.

Predicted Domain #4
Region A:
Residues: [1189-1349]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QETEQADDVS VAPSETSTQE SFFTRYTGKT GGTAKTGASR RTAKNKRREE RKRARGKKGT  60
   61 IYEEEYLVQS VGRLIERLNQ TKPDAVRVVE GLCRRNMREQ AHQIQKNFVE VLDLLKANVK 120
  121 EIYSISEKDR ERVNENGEVY YIPEIPVPEI HDFPKSHIVD F

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle