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View Structure Prediction Details

Protein: NAM2
Organism: Saccharomyces cerevisiae
Length: 894 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NAM2.

Description E-value Query
Range
Subject
Range
gi|107103505 - gi|107103505|ref|ZP_01367423.1| hypothetical protein PaerPA_01004575 [Pseudomonas aeruginosa PACS2]
SYL_PSEAE - Leucyl-tRNA synthetase OS=Pseudomonas aeruginosa GN=leuS PE=3 SV=1
SYL_PSEAE - Leucine--tRNA ligase OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)...
gi|194547865, gi... - gi|84319209|ref|ZP_00967610.1| COG0495: Leucyl-tRNA synthetase [Pseudomonas aeruginosa C3719], gi|25...
gi|126196051, gi... - gi|84325121|ref|ZP_00973161.1| COG0495: Leucyl-tRNA synthetase [Pseudomonas aeruginosa 2192], gi|254...
0.0 [10..892] [1..871]
gi|25292983 - pir||AD2216 leucyl-tRNA synthetase [imported] - Nostoc sp. (strain PCC 7120)
SYL_NOSS1 - Leucine--tRNA ligase OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=leuS PE=3 SV=1
0.0 [10..893] [1..871]
SYLM_SACDO - Leucine--tRNA ligase, mitochondrial OS=Saccharomyces douglasii GN=NAM2 PE=3 SV=1
gi|68519 - gi|68519|pir||SYBYMX leucine-tRNA ligase (EC 6.1.1.4) precursor, mitochondrial - yeast (Saccharomyce...
SYLM_SACPA - Leucine--tRNA ligase, mitochondrial OS=Saccharomyces paradoxus GN=NAM2 PE=3 SV=1
0.0 [1..894] [1..894]
SYLM_YEAST - Leucine--tRNA ligase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NAM2...
NAM2 - Mitochondrial leucyl-tRNA synthetase, also has a direct role in splicing of several mitochondrial gr...
0.0 [1..894] [1..894]
SYL_SYNY3 - Leucyl-tRNA synthetase OS=Synechocystis sp. (strain ATCC 27184 / PCC 6803 / N-1) GN=leuS PE=3 SV=1
gi|7437530 - pir||S77455 leucine-tRNA ligase (EC 6.1.1.4) - Synechocystis sp. (strain PCC 6803)
SYL_SYNY3 - Leucine--tRNA ligase OS=Synechocystis sp. (strain PCC 6803 / Kazusa) GN=leuS PE=3 SV=1
0.0 [10..893] [1..868]
SYL_FUSNN - Leucyl-tRNA synthetase OS=Fusobacterium nucleatum subsp. nucleatum GN=leuS PE=3 SV=1
SYL_FUSNN - Leucine--tRNA ligase OS=Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / CIP 101130 / J...
0.0 [23..894] [6..857]
SYL_PASMU - Leucine--tRNA ligase OS=Pasteurella multocida (strain Pm70) GN=leuS PE=3 SV=1
SYL_PASMU - Leucyl-tRNA synthetase OS=Pasteurella multocida GN=leuS PE=3 SV=1
0.0 [10..894] [1..860]
gi|1778560 - gi|1778560|gb|AAB40843.1| leucine tRNA synthetase [Escherichia coli]
0.0 [10..893] [48..906]
SYL_HAEIN - Leucyl-tRNA synthetase OS=Haemophilus influenzae GN=leuS PE=3 SV=1
SYL_HAEIN - Leucine--tRNA ligase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) GN=leuS P...
0.0 [10..894] [1..860]
gi|15640972, gi|... - gi|9655415|gb|AAF94118.1| leucyl-tRNA synthetase [Vibrio cholerae O1 biovar El Tor str. N16961], gi|...
gi|11271159 - gi|11271159|pir||G82260 leucyl-tRNA synthetase VC0956 [imported] - Vibrio cholerae (strain N16961 s...
gi|153224670, gi... - gi|153224670|ref|ZP_01954547.1| leucyl-tRNA synthetase [Vibrio cholerae MAK 757], gi|124117531|gb|EA...
gi|153823306, gi... - gi|153823306|ref|ZP_01975973.1| leucyl-tRNA synthetase [Vibrio cholerae B33], gi|126519170|gb|EAZ763...
gi|150424488, gi... - gi|254285626|ref|ZP_04960590.1| leucyl-tRNA synthetase [Vibrio cholerae AM-19226], gi|197753063|ref|...
gi|254848087, gi... - gi|254848087|ref|ZP_05237437.1| leucyl-tRNA synthetase [Vibrio cholerae MO10], gi|254843792|gb|EET22...
gi|227009018, gi... - gi|227081130|ref|YP_002809681.1| leucyl-tRNA synthetase [Vibrio cholerae M66-2], gi|227009018|gb|ACP...
0.0 [10..892] [37..892]

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Predicted Domain #1
Region A:
Residues: [1-13]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSRPSSRFL STK

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [707-739]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ILSLEKDLAI SKDYKTPTDL NDAEVKFHND FQR

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [756-789]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TVISDYMKLT NILESALKKG EVRNEMIVQN LQKL

[Run NCBI BLAST on this sequence.]

Region D:
Residues: [823-894]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ERTTESKFKK FQIVVNGRVK FMYTADKNFL KLGRDAVIET LMNLPEGRMY LMNKKIKKFV  60
   61 MKFNVISFLF HK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 290.228787
Match: 1ffyA_
Description: Isoleucyl-tRNA synthetase (IleRS)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [14-49]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RGPGPAVKKL IAIGEKWKQK TTRGLPKQDT LNSGSK

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [61-89]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ALHIGHLRVY VISDSLNRFY KQKGYNVIH

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [122-135]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQQMQSMLA NFDW

[Run NCBI BLAST on this sequence.]

Region D:
Residues: [597-706]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QGMVQGKTYV DPDSGKFLKP DELTFVNDSP DGNTVIIKSN GKVPVVSYEK MSKSKYNGAD  60
   61 PNECILRHGP DATRAHILFQ SPIADALNWD ESKIVGIERW LQKVLHLTKN 

[Run NCBI BLAST on this sequence.]

Region E:
Residues: [740-755]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FLKSITESFE VNLSLN

[Run NCBI BLAST on this sequence.]

Region F:
Residues: [790-822]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTVIYPAVPS ISEEAAEMIN SQMEWNQYRW PEV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 290.228787
Match: 1ffyA_
Description: Isoleucyl-tRNA synthetase (IleRS)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [50-60]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YILCQFPYPS G

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [90-121]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PMGWDAFGLP AENAAIERSI NPAIWTRDNI AK

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [136-167]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DREITTCDPE YYKFTQWIFL KLFENGLAYR KE

[Run NCBI BLAST on this sequence.]

Region D:
Residues: [411-596]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EHSGVLTVVA RKSIMGMLNS EGLSKSVVRY KIRDWLISRQ RYWGTPIPII HCDNCGPVPV  60
   61 PESDLPVKLP ELEGLDTKGN PLSTIDEFVN VACPSCGSPA KRETDTMDTF IDSSWYYFRF 120
  121 LDPKNTSKPF DREIASKNMP VDIYIGGVEH AILHLLYSRF IAKFLGSINA WSDPAGIFEP 180
  181 FKKLVT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 290.228787
Match: 1ffyA_
Description: Isoleucyl-tRNA synthetase (IleRS)
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [168-410]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEINWDPVDM TVLANEQVDA QGRSWRSGAI VEKKQLKQWF LGITKFAPKL KKHLNQLKDW  60
   61 PSNVKQMQKN WIGESVGAEL VFKVADPKFE NLIVFTTRPE TLFAVQYVAL ALDHPIVQKY 120
  121 CEEMPDLKEF IQKSDQLPND TKEGFQLPNI KAVNPLTKEE VPIFAAPYVV SSYGSAPSAV 180
  181 MGCPGHDNRD FEFWQTNCPG EHIKTCIAPF FDDASKVTEQ ERQRIIDTVP FTSTDGVLTK 240
  241 ECG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 290.228787
Match: 1ffyA_
Description: Isoleucyl-tRNA synthetase (IleRS)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle