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View Structure Prediction Details

Protein: GRX8
Organism: Saccharomyces cerevisiae
Length: 109 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GRX8.

Description E-value Query
Range		 Subject
Range
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 6.0E-30 [6..108] [4..102]
gi|116310771, gi... - gi|125548975|gb|EAY94797.1| hypothetical protein OsI_16580 [Oryza sativa Indica Group], gi|116310771...
GRXC6_ORYSA, GLR... - Glutaredoxin-C6 (Glutaredoxin-C2 homolog 1) - Oryza sativa (Rice), (P55142) Glutaredoxin
GRXC6_ORYSJ - Glutaredoxin-C6 OS=Oryza sativa subsp. japonica GN=GRXC6 PE=1 SV=2
 1.0E-29 [6..108] [4..102]
gi|2724050, gi|2... - gi|2724056|gb|AAB92658.1| glutaredoxin type I [Fritillaria agrestis], gi|2724054|gb|AAB92657.1| glut...
 2.0E-29 [6..108] [4..102]
GRXC2_ARATH - Glutaredoxin-C2 OS=Arabidopsis thaliana GN=GRXC2 PE=2 SV=1
 5.0E-29 [5..108] [3..102]
GLRX_RICCO - Glutaredoxin OS=Ricinus communis PE=3 SV=1
 1.0E-28 [5..108] [3..102]
GLRX_SOLLC - Glutaredoxin OS=Solanum lycopersicum PE=3 SV=1
 1.0E-27 [6..108] [4..102]
gi|15637350 - gi|15637350|gb|AAL04507.1|AF406809_1 glutaredoxin [Tilia platyphyllos]
 1.0E-26 [7..102] [5..96]

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Predicted Domain #1
Region A:
Residues: [1-109] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAFVTKAEE MIKSHPYFQL SASWCPDCVY ANSIWNKLNV QDKVFVFDIG SLPRNEQEKW  60
   61 RIAFQKVVGS RNLPTIVVNG KFWGTESQLH RFEAKGTLEE ELTKIGLLP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.09691
Match: 1jhb__
Description: Glutaredoxin (Grx, thioltransferase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity, acting on sulfur group of donors 0.875542098761663 bayes_pls_golite062009
catalytic activity 0.672192331361968 bayes_pls_golite062009
antioxidant activity 0.597906946793766 bayes_pls_golite062009
glutathione peroxidase activity 0.494770751761141 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle