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View Structure Prediction Details

Protein: VPS38
Organism: Saccharomyces cerevisiae
Length: 439 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VPS38.

Description E-value Query
Range
Subject
Range
VPS38 - Part of a Vps34p phosphatidylinositol 3-kinase complex that functions in carboxypeptidase Y (CPY) so...
VPS38_YEAST - Vacuolar protein sorting-associated protein 38 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S28...
0.0 [1..439] [1..439]

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Predicted Domain #1
Region A:
Residues: [1-128]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRFLLSRRQ RHLRMICFHN ISLFRANGDS KLIKEYGDGF IPCFFILESI RGELLYVSEV  60
   61 QSGSLRKLSF QELPKLTGAS TMIVLKLVGL VPSDILCTIS SDKNGIIDDK WCVLCTYTID 120
  121 LNKLQPIN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [129-314]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDTVLITGTN APVLDLIDGS YTLAAEKIKP LKGLVSSHKR NISQVKIKFS LAYSSLLKLN  60
   61 KLLEYSSQVH EEINEISSKI EDDFLSLKNQ NHWYMRTVQK SIETLEKEVL QRKKSKKNIE 120
  121 MAQLESNDTI NHSKTELSLM SQDESINDDY GSIYSRFVQI KDRLDQLRFK KLYQLIGIFH 180
  181 STDLFN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.69897
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [315-439]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDRGYIYFEK PSSVNDVINR LKLKPLNIEI LLRQAGESTK HREYVNSQLG YYLLFLHLTA  60
   61 IQIFKAPLPY RLMYYGSTSV IDSQYPLYFT DQMISKHQAK LIKAIHYFNA DILQFKQILE 120
  121 NYRPT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle