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View Structure Prediction Details

Protein: NIT3
Organism: Saccharomyces cerevisiae
Length: 291 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NIT3.

Description E-value Query
Range
Subject
Range
NIT3 - Nit protein, one of two proteins in S. cerevisiae with similarity to the Nit domain of NitFhit from ...
NIT3_YEAST - Probable hydrolase NIT3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NIT3 PE=1 SV=1
1.0E-85 [1..291] [1..291]
NIT2 - nitrilase family, member 2
8.0E-78 [10..287] [3..271]
NIT2_MOUSE - Omega-amidase NIT2 OS=Mus musculus GN=Nit2 PE=1 SV=1
2.0E-77 [9..287] [2..271]
NILP3_ARATH - Omega-amidase, chloroplastic OS=Arabidopsis thaliana GN=NLP3 PE=1 SV=1
8.0E-73 [10..289] [87..362]
gi|7449038 - pir||B69109 N-carbamoyl-D-amino acid amidohydrolase - Methanobacterium thermoautotrophicum (strain D...
gi|15679799, gi|... - gi|2622943|gb|AAB86277.1| N-carbamoyl-D-amino acid amidohydrolase [Methanothermobacter thermautotrop...
8.0E-73 [11..286] [1..267]

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Predicted Domain #1
Region A:
Residues: [1-291]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSASKILSQK IKVALVQLSG SSPDKMANLQ RAATFIERAM KEQPDTKLVV LPECFNSPYS  60
   61 TDQFRKYSEV INPKEPSTSV QFLSNLANKF KIILVGGTIP ELDPKTDKIY NTSIIFNEDG 120
  121 KLIDKHRKVH LFDVDIPNGI SFHESETLSP GEKSTTIDTK YGKFGVGICY DMRFPELAML 180
  181 SARKGAFAMI YPSAFNTVTG PLHWHLLARS RAVDNQVYVM LCSPARNLQS SYHAYGHSIV 240
  241 VDPRGKIVAE AGEGEEIIYA ELDPEVIESF RQAVPLTKQR RFDVYSDVNA H

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1776.39794
Match: 1f89A_
Description: hypothetical protein yl85
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.64442398754697 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1.33107499649316 bayes_pls_golite062009
hydrolase activity 0.303336127811897 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle