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View Structure Prediction Details

Protein: YLR345W
Organism: Saccharomyces cerevisiae
Length: 509 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YLR345W.

Description E-value Query
Range
Subject
Range
YL345_YEAST - Putative 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase YLR345W OS=Saccharomyces cerevisiae (s...
YLR345W - Similar to 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase enzymes responsible for the metaboli...
0.0 [1..509] [1..509]
F263_RAT - 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 OS=Rattus norvegicus GN=Pfkfb3 PE=2 SV=1
0.0 [65..509] [19..438]
PFKFB1 - 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
0.0 [74..509] [33..443]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [73..509] [30..441]

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Predicted Domain #1
Region A:
Residues: [1-289]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPNVLSDDEE LLNGLGSEIM KPSRQGNHMA RTVKRWVNKE RATTADLKNV NIDGVHGPVN  60
   61 TESYISPGQL YSTDSGNLFH AGRILVVLVG LPATSKTLLS VAITRYTRWL GVRTKSFHFS 120
  121 EYKESAKNIP SDYFCVVPTS KEGVAFVEKL RMQMLNDILA FFNDLSGQLA IYDALNIRKI 180
  181 DRKNLETTFS EIGVKVLFIE SIVSDQEIMN RNIALALESN DYKGLSTDEA IDEYMRRLSV 240
  241 NEPYYEMMTH DEELSYIKYI NLGKQIIVKD NIHGYLVNKI VFFLMNLRQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 638.228787
Match: 1bif__
Description: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [290-509]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKGCVYFARC GTSDKDNYIH DEELNEEGIH YSQVLKDFVL QRIKQKRQAK KNSDSLVEVI  60
   61 DGSHDEDLKT SLIVWTGPRK RTHDTALFFS KEGIKVQQRS ELRQLNPGSI ADLTDQQIMD 120
  121 KFPSEYKESL KDPYHFRFPR AESYHDLAVR MEPLLLEMEH TSKDILIIAH ESTLRVLYGY 180
  181 LMACTCVELP NLNFTRDKLV EISFSPFCNT VELLNIPLTS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 638.228787
Match: 1bif__
Description: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle