YRC Public Data Repository - Protein Structure Prediction

Protein:	MRPL15
Organism:	Saccharomyces cerevisiae
Length:	234 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MRPL15.

Description	E-value	Query Range	Subject Range
MRPL15 - Mitochondrial ribosomal protein of the large subunit	5.0E-53	[1..234]	[1..234]
gi\|37199765, gi\|... - gi\|37681015\|ref\|NP_935624.1\| ribonuclease III [Vibrio vulnificus YJ016], gi\|37199765\|dbj\|BAC95595.1\|...	1.0E-49	[54..231]	[41..203]
gi\|126509385, gi... - gi\|153820073\|ref\|ZP_01972740.1\| ribonuclease III [Vibrio cholerae NCTC 8457], gi\|126509385\|gb\|EAZ719... gi\|254845291, gi... - gi\|254849586\|ref\|ZP_05238936.1\| ribonuclease III [Vibrio cholerae MO10], gi\|254845291\|gb\|EET23705.1\|... RNC_VIBCH - Ribonuclease 3 OS=Vibrio cholerae GN=rnc PE=3 SV=1 gi\|229512326, gi... - gi\|229512326\|ref\|ZP_04401805.1\| ribonuclease III [Vibrio cholerae B33], gi\|229352291\|gb\|EEO17232.1\| ... RNC_VIBCM - Ribonuclease 3 OS=Vibrio cholerae serotype O1 (strain M66-2) GN=rnc PE=3 SV=1 gi\|229519462, gi... - gi\|229519462\|ref\|ZP_04408905.1\| ribonuclease III [Vibrio cholerae RC9], gi\|229344151\|gb\|EEO09126.1\| ... gi\|229507479, gi... - gi\|229507479\|ref\|ZP_04396984.1\| ribonuclease III [Vibrio cholerae BX 330286], gi\|229354984\|gb\|EEO199... gi\|229606984, gi... - gi\|229606984\|ref\|YP_002877632.1\| ribonuclease III [Vibrio cholerae MJ-1236], gi\|229369639\|gb\|ACQ6006... RNC_VIBCH - Ribonuclease 3 OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) GN=rnc PE=3 ... gi\|153222435, gi... - gi\|153222435\|ref\|ZP_01953169.1\| ribonuclease III [Vibrio cholerae MAK 757], gi\|124118872\|gb\|EAY37615... gi\|121590982, gi... - gi\|121590982\|ref\|ZP_01678301.1\| ribonuclease III [Vibrio cholerae 2740-80], gi\|121547159\|gb\|EAX57288...	1.0E-48	[54..231]	[7..169]
RNC_VIBVU - Ribonuclease 3 OS=Vibrio vulnificus (strain CMCP6) GN=rnc PE=3 SV=1 RNC_VIBVU - Ribonuclease 3 OS=Vibrio vulnificus GN=rnc PE=3 SV=1	1.0E-48	[54..231]	[7..169]
gi\|153839958, gi... - gi\|153839958\|ref\|ZP_01992625.1\| ribonuclease III [Vibrio parahaemolyticus AQ3810], gi\|149746517\|gb\|E... RNC_VIBPA - Ribonuclease 3 OS=Vibrio parahaemolyticus GN=rnc PE=3 SV=1 RNC_VIBPA - Ribonuclease 3 OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) GN=rnc PE=3 SV=1	4.0E-48	[54..231]	[7..169]
lcl\|NC_016856.1_... - [gene=rnc] [protein=ribonuclease III] [protein_id=YP_005238688.1] [location=complement(2776380..2777... RNC_SALPK - Ribonuclease 3 OS=Salmonella paratyphi A (strain AKU_12601) GN=rnc PE=3 SV=1 RNC_SALG2 - Ribonuclease 3 OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=rnc PE=3 SV=1 RNC_SALTY - Ribonuclease 3 OS=Salmonella typhimurium GN=rnc PE=3 SV=2 RNC_SALEP - Ribonuclease 3 OS=Salmonella enteritidis PT4 (strain P125109) GN=rnc PE=3 SV=1 RNC_SALPA - Ribonuclease 3 OS=Salmonella paratyphi A GN=rnc PE=3 SV=1 RNC_SALPA - Ribonuclease 3 OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=rnc PE=3 SV=1 RNC_SALTY - Ribonuclease 3 OS=Salmonella typhimurium GN=rnc PE=3 SV=2 gi\|29140810, gi\|... - gi\|29140810\|ref\|NP_804152.1\| ribonuclease III [Salmonella enterica subsp. enterica serovar Typhi str... RNC_SALTY - Ribonuclease 3 OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=rnc PE=3 SV=2	6.0E-48	[55..231]	[9..170]
RNC_SALTI - Ribonuclease 3 OS=Salmonella typhi GN=rnc PE=3 SV=1 RNC_SALTI - Ribonuclease 3 OS=Salmonella typhi GN=rnc PE=3 SV=1 gi\|16761493 - gi\|16761493\|ref\|NP_457110.1\| ribonuclease III [Salmonella enterica subsp. enterica serovar Typhi str...	9.0E-48	[55..231]	[9..170]
RNC_ECO57 - Ribonuclease 3 OS=Escherichia coli O157:H7 GN=rnc PE=3 SV=1 EG10857 - RNase III / RNase III; cleaves double-stranded RNA gi\|12516984, gi\|... - gi\|15803093\|ref\|NP_289124.1\| ribonuclease III [Escherichia coli O157:H7 EDL933], gi\|12516984\|gb\|AAG5... EG10857 - RNase III / RNase III; cleaves double-stranded RNA RNC_ECOUT - Ribonuclease 3 OS=Escherichia coli (strain UTI89 / UPEC) GN=rnc PE=3 SV=1 gi\|13362904, gi\|... - gi\|15832687\|ref\|NP_311460.1\| ribonuclease III [Escherichia coli O157:H7 str. Sakai], gi\|13362904\|dbj... RNC_ECOL5 - Ribonuclease 3 OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=rnc PE=3 SV=1 RNC_SHIF8 - Ribonuclease 3 OS=Shigella flexneri serotype 5b (strain 8401) GN=rnc PE=3 SV=1 RNC_SHIFL - Ribonuclease 3 OS=Shigella flexneri GN=rnc PE=3 SV=1 gi\|24113909, gi\|... - gi\|24113909\|ref\|NP_708419.1\| ribonuclease III [Shigella flexneri 2a str. 301], gi\|24053010\|gb\|AAN441... RNC_ECOL6 - Ribonuclease 3 OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=rnc PE=3 SV=1 gi\|30042225, gi\|... - gi\|30063969\|ref\|NP_838140.1\| ribonuclease III [Shigella flexneri 2a str. 2457T], gi\|30042225\|gb\|AAP1... RNC_ECOLC - Ribonuclease 3 OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=rnc PE=3 SV=1 RNC_ECOK1 - Ribonuclease 3 OS=Escherichia coli O1:K1 / APEC GN=rnc PE=3 SV=1 gi\|124499851, gi... - gi\|124529544\|ref\|ZP_01700514.1\| Ribonuclease III [Escherichia coli B], gi\|124499851\|gb\|EAY47333.1\| R... RNC_ECOLI - Ribonuclease 3 (EC 3.1.26.3) (Ribonuclease III) (RNase III) - Escherichia coli sp\|B7UH07\|RNC_ECO27 - Ribonuclease 3 OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=rnc PE=3 SV=1 gi\|188487921, gi... - gi\|75513177\|ref\|ZP_00735619.1\| COG0571: dsRNA-specific ribonuclease [Escherichia coli 53638], gi\|188... RNC_SHISS - Ribonuclease 3 OS=Shigella sonnei (strain Ss046) GN=rnc PE=3 SV=1 gi\|192958298, gi... - gi\|75237687\|ref\|ZP_00721703.1\| COG0571: dsRNA-specific ribonuclease [Escherichia coli E110019], gi\|1... gi\|193064102, gi... - gi\|75257991\|ref\|ZP_00729465.1\| COG0571: dsRNA-specific ribonuclease [Escherichia coli E22], gi\|19306... gi\|85675458, gi\|... - gi\|89109373\|ref\|AP_003153.1\| RNase III [Escherichia coli str. K-12 substr. W3110], gi\|85675458\|dbj\|B... RNC_SHIDS - Ribonuclease 3 OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=rnc PE=3 SV=1 RNC_SHIBS - Ribonuclease 3 OS=Shigella boydii serotype 4 (strain Sb227) GN=rnc PE=3 SV=1 RNC_SHIB3 - Ribonuclease 3 OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=rnc PE=3 SV=1 RNC_ECO24 - Ribonuclease 3 OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=rnc PE=3 SV=1 gi\|83570803, gi\|... - gi\|83570803\|ref\|ZP_00922246.1\| COG0571: dsRNA-specific ribonuclease [Shigella dysenteriae 1012], gi\|... gi\|194423376, gi... - gi\|83586781\|ref\|ZP_00925412.1\| COG0571: dsRNA-specific ribonuclease [Escherichia coli 101-1], gi\|194... gi\|191167987, gi... - gi\|75228858\|ref\|ZP_00715459.1\| COG0571: dsRNA-specific ribonuclease [Escherichia coli B7A], gi\|19116... RNC_ECOL6 - Ribonuclease 3 OS=Escherichia coli O6 GN=rnc PE=3 SV=1 gi\|191174016, gi... - gi\|75237414\|ref\|ZP_00721449.1\| COG0571: dsRNA-specific ribonuclease [Escherichia coli F11], gi\|19117... RNC_ECOHS - Ribonuclease 3 OS=Escherichia coli O9:H4 (strain HS) GN=rnc PE=3 SV=1 gi\|194412671, gi... - gi\|75209491\|ref\|ZP_00709716.1\| COG0571: dsRNA-specific ribonuclease [Escherichia coli B171], gi\|1944... gi\|237705077, gi... - gi\|237705077\|ref\|ZP_04535558.1\| ribonuclease III [Escherichia sp. 3_2_53FAA], gi\|226901443\|gb\|EEH877... RNC_ECOBW - Ribonuclease 3 OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=rnc PE=3 SV=1 gi\|242378168, gi... - gi\|251785895\|ref\|YP_003000199.1\| hypothetical protein B21_02425 [Escherichia coli BL21], gi\|24237816... gi\|254289303, gi... - gi\|254289303\|ref\|YP_003055051.1\| ribonuclease III [Escherichia coli BL21(DE3)], gi\|253978610\|gb\|ACT4... gi\|253974443, gi... - gi\|254162542\|ref\|YP_003045650.1\| ribonuclease III [Escherichia coli B str. REL606], gi\|253974443\|gb\|... gi\|254593917, gi... - gi\|254794517\|ref\|YP_003079354.1\| RNase III [Escherichia coli O157:H7 str. TW14359], gi\|254593917\|gb\|... RNC_ECODH - Ribonuclease 3 OS=Escherichia coli (strain K12 / DH10B) GN=rnc PE=3 SV=1 RNC_ECOSM - Ribonuclease 3 OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=rnc PE=3 SV=1 gi\|170123495, gi... - gi\|170767161\|ref\|ZP_02901614.1\| ribonuclease III [Escherichia albertii TW07627], gi\|170123495\|gb\|EDS... gi\|187775820, gi... - gi\|187775820\|ref\|ZP_02992726.1\| ribonuclease III [Escherichia coli O157:H7 str. EC4196], gi\|18777060... gi\|189355317, gi... - gi\|189402493\|ref\|ZP_03006738.1\| ribonuclease III [Escherichia coli O157:H7 str. EC4401], gi\|18935531... gi\|189362280, gi... - gi\|189403151\|ref\|ZP_03006973.1\| ribonuclease III [Escherichia coli O157:H7 str. EC4486], gi\|18936228... gi\|189405744, gi... - gi\|189405744\|ref\|ZP_02823956.2\| ribonuclease III [Escherichia coli O157:H7 str. EC508], gi\|189378654... gi\|195936714 - gi\|195936714\|ref\|ZP_03082096.1\| ribonuclease III [Escherichia coli O157:H7 str. EC4024] gi\|188017132, gi... - gi\|188017132\|gb\|EDU55254.1\| ribonuclease III [Escherichia coli O157:H7 str. EC4113], gi\|168748363\|re... gi\|168761188, gi... - gi\|189368381\|gb\|EDU86797.1\| ribonuclease III [Escherichia coli O157:H7 str. EC4501], gi\|168761188\|re... gi\|189003491, gi... - gi\|189003491\|gb\|EDU72477.1\| ribonuclease III [Escherichia coli O157:H7 str. EC4076], gi\|168778544\|re... gi\|168787927, gi... - gi\|189372250\|gb\|EDU90666.1\| ribonuclease III [Escherichia coli O157:H7 str. EC869], gi\|168787927\|ref... RNC_ECO8A - Ribonuclease 3 OS=Escherichia coli O8 (strain IAI1) GN=rnc PE=3 SV=1 RNC_ECO45 - Ribonuclease 3 OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=rnc PE=3 SV=1 RNC_ECO81 - Ribonuclease 3 OS=Escherichia coli O81 (strain ED1a) GN=rnc PE=3 SV=1 RNC_ECO55 - Ribonuclease 3 OS=Escherichia coli (strain 55989 / EAEC) GN=rnc PE=3 SV=1 RNC_ECO7I - Ribonuclease 3 OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=rnc PE=3 SV=1 RNC_ECOLU - Ribonuclease 3 OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=rnc PE=3 SV=1 gi\|208727421, gi... - gi\|208807620\|ref\|ZP_03249957.1\| ribonuclease III [Escherichia coli O157:H7 str. EC4206], gi\|20872742... gi\|208733235, gi... - gi\|208811958\|ref\|ZP_03253287.1\| ribonuclease III [Escherichia coli O157:H7 str. EC4045], gi\|20873323... gi\|208740471, gi... - gi\|208820348\|ref\|ZP_03260668.1\| ribonuclease III [Escherichia coli O157:H7 str. EC4042], gi\|20874047... RNC_ECO5E - Ribonuclease 3 OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=rnc PE=3 SV=1 RNC_ECOSE - Ribonuclease 3 OS=Escherichia coli (strain SE11) GN=rnc PE=3 SV=1 RNC_ECO27 - Ribonuclease 3 OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=rnc PE=3 SV=1 gi\|217327524, gi... - gi\|217327524\|ref\|ZP_03443607.1\| ribonuclease III [Escherichia coli O157:H7 str. TW14588], gi\|2173198... RNC_ESCF3 - Ribonuclease 3 OS=Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73) GN=rnc PE=3 S...	2.0E-47	[55..231]	[9..170]
RNC_PHOPR - Ribonuclease 3 OS=Photobacterium profundum (strain SS9) GN=rnc PE=3 SV=1 RNC_PHOPR - Ribonuclease 3 OS=Photobacterium profundum GN=rnc PE=3 SV=1	5.0E-47	[55..230]	[8..168]

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Predicted Domain #1

Region A:
Residues: [1-234]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSVGKLAYI IYLHKGPRIN GLRRDPESYL RNPSGVLFTE VNAKECQDKV RSILQLPKYG  60
   61 INLSNELILQ CLTHKSFAHG SKPYNEKLNL LGAQFLKLQT CIHSLKNGSP AESCENGQLS 120
  121 LQFSNLGTKF AKELTSKNTA CTFVKLHNLD PFIFWKMRDP IKDGHINGET TIFASVLNAF 180
  181 IGAILSTNGS EKAAKFIQGS LLDKEDLHSL VNIANENVAS AKAKISDKEN KAFL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	39.0
Match:	1o0wA_
Description:	RNase III endonuclease catalytic domain; RNase III, C-terminal domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits