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View Structure Prediction Details

Protein: THI7
Organism: Saccharomyces cerevisiae
Length: 598 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for THI7.

Description E-value Query
Range
Subject
Range
THI7_YEAST - Thiamine transporter OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=THI7 PE=1 SV=1
THI7 - Plasma membrane transporter responsible for the uptake of thiamine, member of the major facilitator ...
0.0 [1..598] [1..598]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
0.0 [2..543] [70..624]
YEME_SCHPO - Uncharacterized permease C29B12.14c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC29...
SPAC29B12.14c - purine transporter
0.0 [9..504] [19..514]
fur4 - uracil permease
FUR4_SCHPO - Uracil permease OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=fur4 PE=1 SV=2
0.0 [2..506] [8..518]

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Predicted Domain #1
Region A:
Residues: [1-546]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFGSKVSRA LRFLEIPVKD RASVSFLKNP DLQPIKSANQ TWGFWSNFAY WGVMSFSVGT  60
   61 WMSASSALGV GLSYPETIGT FIVGDVLTII FTLANSCPGY DWKVGFTLAQ RFVFGIYGSA 120
  121 FGIIIRILMS IVNYGSNAWV GGLCINMILD SWSHHYLHLP NTLSSKVAMT TKELIGFIIF 180
  181 HVLTAFCYLM KPYHMNYILI WSCVATFFSM LGMVIYLAKQ AHGVGELFTS TKSTATGSTK 240
  241 AWAWVYMISY WFGSVSPGST NQSDYSRFGS SNWAIWAGTI CALLIPTTLI PVFGVIGAST 300
  301 CDKLYGEQYW MPMDIFNHWL TTNYSAGARA GAFFCGLSFV LSQMSYTISN CGFASGMDLA 360
  361 GLLPKYVDIK RGALFAACVS WACLPWNFYN SSSTFLTVMS SFGVVMTPII SVMICDNFLI 420
  421 RKRQYSITNA FILKGEYYFT KGVNWRAIVA WVCGMTPGLP GIAWEVNNDY FHNTGIVNFF 480
  481 YGDSFFSFLI SFFVYWGLCL LFPFKITVKH DDKDYYGAFT DEEARKKGMV PYSEISEEEI 540
  541 RAYTLG

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 179.017729
Match: PF02133
Description: Permease for cytosine/purines, uracil, thiamine, allantoin

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [547-598]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGYTTGHEYR PEGSDDEIPE LVKTSSENTN EFEIVHHKNN EKQSSTASEK AA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle