YRC Public Data Repository - Protein Structure Prediction

Protein:	COQ9
Organism:	Saccharomyces cerevisiae
Length:	260 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COQ9.

Description	E-value	Query Range	Subject Range
COQ9 - Protein required for ubiquinone (coenzyme Q) biosynthesis and respiratory growth; localizes to the m... gi\|207342970 - gi\|207342970\|gb\|EDZ70577.1\| YLR201Cp-like protein [Saccharomyces cerevisiae AWRI1631] gi\|190405268 - gi\|190405268\|gb\|EDV08535.1\| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a] COQ9_YEAST - Ubiquinone biosynthesis protein COQ9, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 ... gi\|151941043 - gi\|151941043\|gb\|EDN59423.1\| coenzyme Q [Saccharomyces cerevisiae YJM789]	2.0E-99	[1..260]	[1..260]
COQ9 - coenzyme Q9 homolog (S. cerevisiae) gi\|190690429, gi... - gi\|190691807\|gb\|ACE87678.1\| coenzyme Q9 homolog (S. cerevisiae) protein [synthetic construct], gi\|19...	4.0E-73	[18..242]	[77..294]
gi\|8954052, gi\|1... - gi\|8954052\|gb\|AAF82225.1\|AC069143_1 Contains similarity to a HSPC326 mRNA from Homo sapiens gb\|AF161...	2.0E-65	[38..242]	[89..280]
COQ9_SCHPO - Ubiquinone biosynthesis protein coq9, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / ATCC ... coq9 - ubiquinone biosynthesis protein Coq9	2.0E-61	[15..256]	[32..248]
gi\|18447632 - gi\|18447632\|gb\|AAL68377.1\| SD02734p [Drosophila melanogaster]	6.0E-59	[21..239]	[97..298]
gi\|7467813, gi\|3... - pir\|\|A71667 hypothetical protein RP616 - Rickettsia prowazekii, gi\|3861159\|emb\|CAA15059.1\| unknown [... gi\|15604465 - gi\|15604465\|ref\|NP_220983.1\| hypothetical protein RP616 [Rickettsia prowazekii str. Madrid E]	4.0E-52	[33..241]	[1..193]
gi\|25365045 - pir\|\|F97818 hypothetical protein RC0950 [imported] - Rickettsia conorii (strain Malish 7) gi\|15892873, gi\|... - gi\|15892873\|ref\|NP_360587.1\| hypothetical protein RC0950 [Rickettsia conorii str. Malish 7], gi\|1562...	3.0E-51	[28..239]	[14..209]
gi\|220965514, gi... - gi\|221236341\|ref\|YP_002518778.1\| hypothetical protein CCNA_03405 [Caulobacter crescentus NA1000], gi... gi\|25399887 - pir\|\|F87657 conserved hypothetical protein CC3296 [imported] - Caulobacter crescentus gi\|13424990, gi\|... - gi\|16127526\|ref\|NP_422090.1\| hypothetical protein CC_3296 [Caulobacter crescentus CB15], gi\|13424990...	2.0E-48	[19..233]	[2..200]

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Predicted Domain #1

Region A:
Residues: [1-106]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLCRNTARTG CKFFRLYHSN PIEHVKPIHI KPLTYGKESP QYKVLSLALQ KFVPEHGFSE  60
   61 RSIVESLNEL GYPSSMISSI GAPNSPSFFH SSTAVMELIK FQLVDK

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [141-161]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IGGHLSELMS QLAIPSAFLF E

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	12.85
Match:	1jtxB
Description:	Multidrug binding protein QacR
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	2.167503712607	bayes_pls_golite062009
DNA binding	1.95239572065848	bayes_pls_golite062009
nucleic acid binding	1.91459297185958	bayes_pls_golite062009
transcription factor activity	1.52599344168604	bayes_pls_golite062009
sequence-specific DNA binding	0.453985309086988	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.291481908925617	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [107-140]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RYRLTEGINP DVTPQYKLPS LEHLLLKRLE MDKP

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [162-260]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TAIPELHRLS DDMIYFSNEK DHHDSAWYAK RLAVSSTYIG SKLFMAQDKS HNYKETFTFA  60
   61 KDKLHRVMRL GEYYNNTEEF AWYTLMSTVN LIKSQLVRG

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	12.85
Match:	1jtxB
Description:	Multidrug binding protein QacR
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: