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View Structure Prediction Details

Protein: RFX1
Organism: Saccharomyces cerevisiae
Length: 811 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RFX1.

Description E-value Query
Range
Subject
Range
gi|1077406 - gi|1077406|pir||S51421 hypothetical protein YLR176c - yeast (Saccharomyces cerevisiae)
653.0 [0..49] [811..9]
gi|109111669 - gi|109111669|ref|XP_001086606.1| PREDICTED: similar to regulatory factor X3 isoform b isoform 5 [Mac...
639.0 [0..160] [801..51]
gi|1082336, gi|5... - gi|57209027|emb|CAI41216.1| regulatory factor X, 3 (influences HLA class II expression) [Homo sapien...
636.0 [0..160] [801..51]
gi|73946688 - gi|73946688|ref|XP_533540.2| PREDICTED: similar to regulatory factor X3 isoform b isoform 1 [Canis f...
629.0 [0..160] [801..51]
RFX3_MACFA - Transcription factor RFX3 OS=Macaca fascicularis GN=RFX3 PE=2 SV=1
626.0 [0..160] [801..51]
RFX3_MOUSE - Transcription factor RFX3 OS=Mus musculus GN=Rfx3 PE=1 SV=2
622.0 [0..160] [801..51]

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Predicted Domain #1
Region A:
Residues: [1-230]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVIFKERKPT ENLFTRKIPA KYFIFSPSFL SVHYFEFYLP MSGDNNIEPT SRGSNDNSNG  60
   61 PSNGSSVNSN RYSLNAPKYS SQPPPASHTY LPPMSVNIPP IASKSSSIYS LLHQSSPRPE 120
  121 TPNPILPPLI GSGPGSHKPS PTPTQPPAQP ATQRQPATYS VYPASISLNR SNSSAYPLSF 180
  181 KSEETLNNNP PTAAKRTNTF PSIPSSTKKQ KTSQEKRISS ISRRNTQEII 

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 12.57
Match:
Description: No description for 1deqA was found.

Predicted Domain #2
Region A:
Residues: [231-284]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKQIAENNKS KTIEEYAQIV KHAEIKVLSM DSQNTSKAAL QLAEQNRERE RQVF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [285-360]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ALLWLMKNCK SQHDSYVPRG KIFAQYASSC SQNNLKPLSQ ASLGKLIRTV FPDLTTRRLG  60
   61 MRGQSKYHYC GLKLTV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 156.927757
Match: 1dp7P
Description: Class II MHC transcription factor RFX1
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [361-557]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NESGSVSLNN NNASLSLVHN NDPISPLSSP SPSSPSPQVP NVSSPFSLNR KSLSRTGSPV  60
   61 KQSSNDNPNE PELESQHPNE TEANKLDSLP PAANNPTGTL SSDELTFTHD LIEKVFNCND 120
  121 KLSDNYNTQI LSNTEHPLLT SYKLDFPKIP AGVLPTDTDS DVISSLESLY HIHCNSVYEC 180
  181 IKFLKSDNIS NALFFSN

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 11.48
Match:
Description: No description for 1i3qA was found.

Predicted Domain #5
Region A:
Residues: [558-666]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNSISPTMFN LFISEPLIDW VTKCDLITYT GLIKFFSQFI IHSNEISDSI IQKLESMIKL  60
   61 LPEQINKAVL ELPKALVQRK LSIINNFTKL VKKLIKLLKF ILNFLKSFP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.983 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain

Predicted Domain #6
Region A:
Residues: [667-811]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IFKSGMNNDW KNIVNLDDIL EMMINEDDTN SETNTIMQHL QGFCQVFVTK FLNSSMSVSN  60
   61 DPSVSIECKS LNEMIKDFCS FISLQSKFSC LKLIDCSTRF RNAIIGDISL KSNENLLSWL 120
  121 FLNNVMGQLL NYCFEVMKFV NGLKV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle