YRC Public Data Repository - Protein Structure Prediction

Protein:	CBF5
Organism:	Saccharomyces cerevisiae
Length:	483 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CBF5.

Description	E-value	Query Range	Subject Range
CBF5 - Pseudouridine synthase catalytic subunit of box H/ACA small nucleolar ribonucleoprotein particles (s... CBF5_YEAST - H/ACA ribonucleoprotein complex subunit 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) G...	0.0	[1..400]	[1..400]
DKC1_MOUSE - H/ACA ribonucleoprotein complex subunit 4 OS=Mus musculus GN=Dkc1 PE=1 SV=3	0.0	[4..430]	[34..460]
gi\|108708379, gi... - gi\|34896278\|ref\|NP_909483.1\| putative centromere/microtubule binding protein [Oryza sativa], gi\|2156...	0.0	[4..471]	[52..517]
CBF5_CANAL - Centromere/microtubule-binding protein CBF5 OS=Candida albicans GN=CBF5 PE=3 SV=1 gi\|238878534 - gi\|238878534\|gb\|EEQ42172.1\| centromere/microtubule-binding protein CBF5 [Candida albicans WO-1] CBF5_CANAL - Centromere/microtubule-binding protein CBF5 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=C...	0.0	[2..426]	[3..425]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[4..430]	[35..461]
CBF5_ASPFU - Centromere/microtubule-binding protein cbf5 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / ... CBF5_ASPFU - Centromere/microtubule-binding protein cbf5 OS=Aspergillus fumigatus GN=cbf5 PE=2 SV=1 gi\|159126206 - gi\|159126206\|gb\|EDP51322.1\| pseudouridylate synthase family protein [Aspergillus fumigatus A1163]	0.0	[5..445]	[11..452]
DKC1_RAT - H/ACA ribonucleoprotein complex subunit 4 OS=Rattus norvegicus GN=Dkc1 PE=1 SV=4	0.0	[4..430]	[35..461]
gi\|7378766 - gi\|7378766\|emb\|CAB85492.1\| putative kinetochore protein [Hordeum vulgare subsp. vulgare]	0.0	[4..358]	[47..401]
gi\|123998617, gi... - gi\|123998617\|gb\|ABM86910.1\| dyskeratosis congenita 1, dyskerin [synthetic construct], gi\|123984635\|g... gi\|14602859 - gi\|14602859\|gb\|AAH09928.1\| Dyskeratosis congenita 1, dyskerin [Homo sapiens]	0.0	[4..433]	[34..463]
gi\|19528063 - gi\|19528063\|gb\|AAL90146.1\| AT23018p [Drosophila melanogaster]	0.0	[3..430]	[31..458]

Back

Predicted Domain #1

Region A:
Residues: [1-264]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKEDFVIKP EAAGASTDTS EWPLLLKNFD KLLVRSGHYT PIPAGSSPLK RDLKSYISSG  60
   61 VINLDKPSNP SSHEVVAWIK RILRCEKTGH SGTLDPKVTG CLIVCIDRAT RLVKSQQGAG 120
  121 KEYVCIVRLH DALKDEKDLG RSLENLTGAL FQRPPLISAV KRQLRVRTIY ESNLIEFDNK 180
  181 RNLGVFWASC EAGTYMRTLC VHLGMLLGVG GHMQELRRVR SGALSENDNM VTLHDVMDAQ 240
  241 WVYDNTRDES YLRSIIQPLE TLLV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	219.69897
Match:	1k8wA_
Description:	Pseudouridine synthase II TruB, C-terminal domain; Pseudouridine synthase II TruB
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [265-344]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GYKRIVVKDS AVNAVCYGAK LMIPGLLRYE EGIELYDEIV LITTKGEAIA VAIAQMSTVD  60
   61 LASCDHGVVA SVKRCIMERD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	219.69897
Match:	1k8wA_
Description:	Pseudouridine synthase II TruB, C-terminal domain; Pseudouridine synthase II TruB
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [345-483]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LYPRRWGLGP VAQKKKQMKA DGKLDKYGRV NENTPEQWKK EYVPLDNAEQ STSSSQETKE  60
   61 TEEEPKKAKE DSLIKEVETE KEEVKEDDSK KEKKEKKDKK EKKEKKEKKD KKEKKEKKEK 120
  121 KRKSEDGDSE EKKSKKSKK

[Run NCBI BLAST on this sequence.]

Detection Method:	Pcons
Confidence:	1.56
Match:	1c1gA
Description:	Tropomyosin
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits