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View Structure Prediction Details

Protein: MAS1
Organism: Saccharomyces cerevisiae
Length: 462 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MAS1.

Description E-value Query
Range
Subject
Range
gi|3342006, gi|4... - gi|4758734|ref|NP_004270.1| peptidase (mitochondrial processing) beta [Homo sapiens], gi|3342006|gb|...
0.0 [8..460] [41..484]
MPPB_MOUSE - Mitochondrial-processing peptidase subunit beta OS=Mus musculus GN=Pmpcb PE=1 SV=1
0.0 [8..460] [41..484]
MAS1 - Smaller subunit of the mitochondrial processing protease (MPP), essential processing enzyme that cle...
MPPB_YEAST - Mitochondrial-processing peptidase subunit beta OS=Saccharomyces cerevisiae (strain ATCC 204508 / S2...
0.0 [1..462] [1..462]
gi|397699 - gi|397699|dbj|BAA03007.1| mitochondrial processing protease [Rattus norvegicus]
0.0 [8..460] [39..482]
gi|195570810, gi... - gi|195570810|ref|XP_002103397.1| GD18983 [Drosophila simulans], gi|194199324|gb|EDX12900.1| GD18983 ...
gi|220945206, gi... - gi|220955020|gb|ACL90053.1| CG3731-PA [synthetic construct], gi|220945206|gb|ACL85146.1| CG3731-PA [...
gi|195328891, gi... - gi|195328891|ref|XP_002031145.1| GM24191 [Drosophila sechellia], gi|194120088|gb|EDW42131.1| GM24191...
CG3731-PB, CG3731-PA - This gene is referred to in FlyBase by the symbol Dmel\CG3731 (CG3731, FBgn0038271). It is a protein...
0.0 [1..460] [21..465]
gi|12802327 - gi|12802327|gb|AAK07827.1|AF297643_1 mitochondrial processing peptidase beta subunit [Cucumis melo]
0.0 [21..459] [89..522]
MPPB_ARATH - Probable mitochondrial-processing peptidase subunit beta, mitochondrial OS=Arabidopsis thaliana GN=A...
0.0 [15..459] [86..525]
QCR1_BOVIN - Cytochrome b-c1 complex subunit 1, mitochondrial OS=Bos taurus GN=UQCRC1 PE=1 SV=2
0.0 [4..460] [27..475]

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Predicted Domain #1
Region A:
Residues: [1-155]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSRTASKFR NTRRLLSTIS SQIPGTRTSK LPNGLTIATE YIPNTSSATV GIFVDAGSRA  60
   61 ENVKNNGTAH FLEHLAFKGT QNRSQQGIEL EIENIGSHLN AYTSRENTVY YAKSLQEDIP 120
  121 KAVDILSDIL TKSVLDNSAI ERERDVIIRE SEEVD

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [174-247]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPLGRTILGP IKNIKSITRT DLKDYITKNY KGDRMVLAGA GAVDHEKLVQ YAQKYFGHVP  60
   61 KSESPVPLGS PRGP

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [387-411]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLDGSTAIVE DIGRQVVTTG KRLSP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10127.0
Match: 1hr6B_
Description: Mitochondrial processing peptidase (MPP) beta chain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor 10.0305725791312 bayes_pls_golite062009
ubiquinol-cytochrome-c reductase activity 10.0305725791312 bayes_pls_golite062009
metallopeptidase activity 7.31794755224524 bayes_pls_golite062009
metalloendopeptidase activity 7.31174048559335 bayes_pls_golite062009
peptidase activity 7.05972470989638 bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors 6.64269017601856 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 6.57226784092621 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 4.17510847735476 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 4.03221088799464 bayes_pls_golite062009
oxidoreductase activity 3.89224384280888 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 3.48526983761385 bayes_pls_golite062009
endopeptidase activity 3.25021389096625 bayes_pls_golite062009
hydrolase activity 2.79262298779436 bayes_pls_golite062009
transporter activity 1.55442313420533 bayes_pls_golite062009
binding 1.51460850438647 bayes_pls_golite062009
transmembrane transporter activity 1.40378628474509 bayes_pls_golite062009
catalytic activity 1.30647052031202 bayes_pls_golite062009
substrate-specific transporter activity 1.29599547747567 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.16717310870379 bayes_pls_golite062009
signal transducer activity 1.12122807250795 bayes_pls_golite062009
molecular transducer activity 1.12122807250795 bayes_pls_golite062009
ion transmembrane transporter activity 1.05022391589259 bayes_pls_golite062009
cation transmembrane transporter activity 0.961854978876222 bayes_pls_golite062009
protein binding 0.236143103582996 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.11486391789734 bayes_pls_golite062009
pyrophosphatase activity 0.077701103001661 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.0688257218639591 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.0662171656580391 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [156-173]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KMYDEVVFDH LHEITYKD

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [248-386]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPVFCRGERF IKENTLPTTH IAIALEGVSW SAPDYFVALA TQAIVGNWDR AIGTGTNSPS  60
   61 PLAVAASQNG SLANSYMSFS TSYADSGLWG MYIVTDSNEH NVQLIVNEIL KEWKRIKSGK 120
  121 ISDAEVNRAK AQLKAALLL

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [412-462]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEVFEQVDKI TKDDIIMWAN YRLQNKPVSM VALGNTSTVP NVSYIEEKLN Q

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10127.0
Match: 1hr6B_
Description: Mitochondrial processing peptidase (MPP) beta chain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle