YRC Public Data Repository - Protein Structure Prediction

Protein:	ASP3-4, ASP3-1, ...
Organism:	Saccharomyces cerevisiae
Length:	362 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ASP3-4, ASP3-1, ....

Description	E-value	Query Range	Subject Range
ASP3-4, ASP3-1, ... - Cell-wall L-asparaginase II, involved in asparagine catabolism; expression is induced during nitroge... ASP24_YEAST, ASP... - L-asparaginase 2-4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ASP3-4 PE=1 SV=1, L-a...	0.0	[1..362]	[1..362]
GATD_PYRHO - Glutamyl-tRNA(Gln) amidotransferase subunit D OS=Pyrococcus horikoshii (strain ATCC 700860 / DSM 124... GATD_PYRHO - Glutamyl-tRNA(Gln) amidotransferase subunit D OS=Pyrococcus horikoshii GN=gatD PE=3 SV=1	0.0	[5..362]	[45..425]
GATD_PYRAB - Glutamyl-tRNA(Gln) amidotransferase subunit D OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=gatD PE=1... GATD_PYRAB - Glutamyl-tRNA(Gln) amidotransferase subunit D OS=Pyrococcus abyssi GN=gatD PE=1 SV=1	0.0	[5..362]	[45..425]
GATD_PYRFU - Glutamyl-tRNA(Gln) amidotransferase subunit D OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 /... GATD_PYRFU - Glutamyl-tRNA(Gln) amidotransferase subunit D OS=Pyrococcus furiosus GN=gatD PE=3 SV=1	0.0	[5..362]	[45..425]
gi\|668327 - gi\|668327\|gb\|AAA62276.1\| chimeric immunoglobulin-L-asparaginase [synthetic construct]	0.0	[31..358]	[289..614]
gi\|7451280, gi\|6... - gi\|7451280\|pir\|\|C69194 L-asparaginase I - Methanobacterium thermoautotrophicum (strain Delta H), gi... GATD_METTH - Glutamyl-tRNA(Gln) amidotransferase subunit D OS=Methanothermobacter thermautotrophicus (strain ATCC...	0.0	[7..362]	[47..422]
gi\|189363657, gi... - gi\|189363657\|gb\|EDU82076.1\| L-asparaginase 2 [Escherichia coli O157:H7 str. EC4486], gi\|168766964\|re... gi\|189369341, gi... - gi\|189369341\|gb\|EDU87757.1\| L-asparaginase 2 [Escherichia coli O157:H7 str. EC4501], gi\|168760099\|re... gi\|189358583, gi... - gi\|189358583\|gb\|EDU77002.1\| L-asparaginase 2 [Escherichia coli O157:H7 str. EC4401], gi\|168753909\|re... gi\|168747551, gi... - gi\|188017927\|gb\|EDU56049.1\| L-asparaginase 2 [Escherichia coli O157:H7 str. EC4113], gi\|168747551\|re... gi\|217327513, gi... - gi\|217327513\|ref\|ZP_03443596.1\| L-asparaginase 2 [Escherichia coli O157:H7 str. TW14588], gi\|2173198... gi\|209158459, gi... - gi\|209397059\|ref\|YP_002272437.1\| L-asparaginase 2 [Escherichia coli O157:H7 str. EC4115], gi\|2091584... gi\|15833087, gi\|... - gi\|15833087\|ref\|NP_311860.1\| L-asparaginase II [Escherichia coli O157:H7 str. Sakai], gi\|13363305\|db... gi\|189379870, gi... - gi\|189379870\|gb\|EDU98286.1\| L-asparaginase 2 [Escherichia coli O157:H7 str. EC508], gi\|168797532\|ref... gi\|189374047, gi... - gi\|189374047\|gb\|EDU92463.1\| L-asparaginase 2 [Escherichia coli O157:H7 str. EC869], gi\|168785815\|ref... gi\|168781816, gi... - gi\|189000626\|gb\|EDU69612.1\| L-asparaginase 2 [Escherichia coli O157:H7 str. EC4076], gi\|168781816\|re... gi\|187770804, gi... - gi\|187770804\|gb\|EDU34648.1\| L-asparaginase 2 [Escherichia coli O157:H7 str. EC4196], gi\|168773404\|re... gi\|15833087, gi\|... - gi\|15833087\|ref\|NP_311860.1\| periplasmic L-asparaginase II [Escherichia coli O157:H7], gi\|13363305\|d... gi\|208820500, gi... - gi\|208820500\|ref\|ZP_03260820.1\| L-asparaginase 2 [Escherichia coli O157:H7 str. EC4042], gi\|20874062... gi\|25290105, gi\|... - pir\|\|D85953 periplasmic L-asparaginase II [imported] - Escherichia coli (strain O157:H7, substrain ... gi\|208734271, gi... - gi\|208812994\|ref\|ZP_03254323.1\| L-asparaginase 2 [Escherichia coli O157:H7 str. EC4045], gi\|20873427... gi\|254594309, gi... - gi\|254794909\|ref\|YP_003079746.1\| periplasmic L-asparaginase II [Escherichia coli O157:H7 str. TW1435... gi\|208727388, gi... - gi\|208807587\|ref\|ZP_03249924.1\| L-asparaginase 2 [Escherichia coli O157:H7 str. EC4206], gi\|20872738... gi\|15803496, gi\|... - gi\|15803496\|ref\|NP_289529.1\| L-asparaginase II [Escherichia coli O157:H7 EDL933], gi\|12517506\|gb\|AAG... gi\|195937095 - gi\|195937095\|ref\|ZP_03082477.1\| L-asparaginase II [Escherichia coli O157:H7 str. EC4024]	0.0	[6..358]	[7..347]
gi\|238902079, gi... - gi\|238902079\|ref\|YP_002927875.1\| periplasmic L-asparaginase II [Escherichia coli BW2952], gi\|2388620... gi\|253772205, gi... - gi\|253772205\|ref\|YP_003035036.1\| L-asparaginase, type II [Escherichia coli BL21(DE3)], gi\|253323249\|... ASG2_ECOLI, ASPG... - L-asparaginase 2 precursor (EC 3.5.1.1) (L-asparaginase II) (L-asparagine amidohydrolase II) (L-ASNa... EG10046 - periplasmic L-asparaginase 2 / L-asparaginase 2, periplasmic, high affinity EG10046 - periplasmic L-asparaginase 2 / L-asparaginase 2, periplasmic, high affinity gi\|85675767, gi\|... - gi\|89109734\|ref\|AP_003514.1\| periplasmic L-asparaginase II [Escherichia coli str. K-12 substr. W3110... gi\|169890344, gi... - gi\|170082509\|ref\|YP_001731829.1\| periplasmic L-asparaginase II [Escherichia coli str. K-12 substr. D...	0.0	[6..358]	[7..347]
gi\|213850154 - gi\|213850154\|ref\|ZP_03381052.1\| L-asparaginase II [Salmonella enterica subsp. enterica serovar Typhi... gi\|213648212 - gi\|213648212\|ref\|ZP_03378265.1\| L-asparaginase II [Salmonella enterica subsp. enterica serovar Typhi... gi\|224584899, gi... - gi\|224584899\|ref\|YP_002638698.1\| L-asparaginase [Salmonella enterica subsp. enterica serovar Paratyp... gi\|214001049 - gi\|214001049\|ref\|ZP_03411784.1\| L-asparaginase II [Salmonella enterica subsp. enterica serovar Typhi... gi\|213051774 - gi\|213051774\|ref\|ZP_03344652.1\| L-asparaginase II [Salmonella enterica subsp. enterica serovar Typhi... gi\|204928057, gi... - gi\|204928057\|ref\|ZP_03219257.1\| L-asparaginase 2 [Salmonella enterica subsp. enterica serovar Javian... gi\|213609095 - gi\|213609095\|ref\|ZP_03368921.1\| L-asparaginase II [Salmonella enterica subsp. enterica serovar Typhi... gi\|213424103 - gi\|213424103\|ref\|ZP_03356996.1\| L-asparaginase II [Salmonella enterica subsp. enterica serovar Typhi... gi\|197095450, gi... - gi\|197363973\|ref\|YP_002143610.1\| L-asparaginase II [Salmonella enterica subsp. enterica serovar Para... gi\|197248611, gi... - gi\|197248611\|ref\|YP_002148020.1\| L-asparaginase 2 [Salmonella enterica subsp. enterica serovar Agona... gi\|199603918, gi... - gi\|200386820\|ref\|ZP_03213432.1\| L-asparaginase 2 [Salmonella enterica subsp. enterica serovar Vircho... gi\|198241840, gi... - gi\|198241840\|ref\|YP_002217081.1\| L-asparaginase 2 [Salmonella enterica subsp. enterica serovar Dubli... lcl\|NC_016856.1_... - [gene=ansB] [protein=L-asparaginase II] [protein_id=YP_005239252.1] [location=complement(3284603..32... gi\|29139002, gi\|... - gi\|29143368\|ref\|NP_806710.1\| L-asparaginase II [Salmonella enterica subsp. enterica serovar Typhi st... gi\|16761881 - gi\|16761881\|ref\|NP_457498.1\| L-asparaginase II [Salmonella enterica subsp. enterica serovar Typhi st... gi\|25290114, gi\|... - gi\|25290114\|pir\|\|AB0879 asparaginase (EC 3.5.1.1) - Salmonella enterica subsp. enterica serovar Typh... gi\|16421659, gi\|... - gi\|16766407\|ref\|NP_462022.1\| L-asparaginase II [Salmonella typhimurium LT2], gi\|16421659\|gb\|AAL21981... gi\|56129301, gi\|... - gi\|56415044\|ref\|YP_152119.1\| L-asparaginase II [Salmonella enterica subsp. enterica serovar Paratyph... gi\|205347033, gi... - gi\|205347033\|gb\|EDZ33664.1\| L-asparaginase 2 [Salmonella enterica subsp. enterica serovar Hadar str.... gi\|168234343, gi... - gi\|205331688\|gb\|EDZ18452.1\| L-asparaginase 2 [Salmonella enterica subsp. enterica serovar Kentucky s... gi\|194455085, gi... - gi\|194468721\|ref\|ZP_03074705.1\| L-asparaginase 2 [Salmonella enterica subsp. enterica serovar Kentuc... gi\|238909904 - gi\|238909904\|ref\|ZP_04653741.1\| L-asparaginase II [Salmonella enterica subsp. enterica serovar Tenne... gi\|194404359, gi... - gi\|194445696\|ref\|YP_002042365.1\| L-asparaginase 2 [Salmonella enterica subsp. enterica serovar Newpo... gi\|205331124, gi... - gi\|205331124\|gb\|EDZ17888.1\| L-asparaginase 2 [Salmonella enterica subsp. enterica serovar 4,[5],12:i... gi\|167552002, gi... - gi\|205323300\|gb\|EDZ11139.1\| L-asparaginase 2 [Salmonella enterica subsp. enterica serovar Saintpaul ...	0.0	[6..358]	[7..347]
gi\|148719178, gi... - gi\|148827936\|ref\|YP_001292689.1\| L-asparaginase II [Haemophilus influenzae PittGG], gi\|148719178\|gb\|... gi\|145630486 - gi\|145630486\|ref\|ZP_01786266.1\| L-asparaginase II [Haemophilus influenzae 22.4-21] ASPG2_HAEIN, ASG... - Probable L-asparaginase periplasmic OS=Haemophilus influenzae GN=ansB PE=1 SV=1, (P43843) Probable L... ASPG2_HAEIN - Probable L-asparaginase periplasmic OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 ... gi\|144983876 - gi\|144983876\|gb\|EDJ91318.1\| L-asparaginase II [Haemophilus influenzae R3021]	0.0	[9..357]	[1..347]

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Predicted Domain #1

Region A:
Residues: [1-245]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSLNTLLLS LFVAMSSGAP LLKIREEKNS SLPSIKIFGT GGTIASKGST SATTAGYSVG  60
   61 LTVNDLIEAV PSLAEKANLD YLQVSNVGSN SLNYTHLIPL YHGISEALAS DDYAGAVVTH 120
  121 GTDTMEETAF FLDLTINSEK PVCIAGAMRP ATATSADGPM NLYQAVSIAA SEKSLGRGTM 180
  181 ITLNDRIASG FWTTKMNANS LDTFRADEQG YLGYFSNDDV EFYYPPVKPN GWQFFDISNL 240
  241 TDPSE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	735.54902
Match:	1hfjA_
Description:	Asparaginase type II
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
asparaginase activity	5.31552786314061	bayes_pls_golite062009
hydrolase activity	4.24082880889802	bayes_pls_golite062009
catalytic activity	1.35076351157997	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	0.739997194025722	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	0.584091474722373	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [246-362]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPEVIILYSY QGLNPELIVK AVKDLGAKGI VLAGSGAGSW TATGSIVNEQ LYEEYGIPIV  60
   61 HSRRTADGTV PPDDAPEYAI GSGYLNPQKS RILLQLCLYS GYGMDQIRSV FSGVYGG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	735.54902
Match:	1hfjA_
Description:	Asparaginase type II
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: