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View Structure Prediction Details

Protein: REX3
Organism: Saccharomyces cerevisiae
Length: 404 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for REX3.

Description E-value Query
Range
Subject
Range
REXO3_YEAST - RNA exonuclease 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=REX3 PE=1 SV=1
REX3 - RNA exonuclease; required for maturation of the RNA component of RNase MRP; functions redundantly wi...
0.0 [1..404] [1..404]
gi|6329915 - gi|6329915|dbj|BAA86452.1| KIAA1138 protein [Homo sapiens]
5.0E-91 [24..400] [858..1238]
gi|12839213, gi|... - gi|148699589|gb|EDL31536.1| REX1, RNA exonuclease 1 homolog (S. cerevisiae), isoform CRA_d [Mus musc...
4.0E-90 [24..400] [148..535]
GOR_PANTR - Exonuclease GOR - Pan troglodytes (Chimpanzee)
gi|243898 - gi|243898|gb|AAB21194.1| GOR [Pan]
2.0E-80 [20..395] [56..397]
GOR_PANTR - Exonuclease GOR - Pan troglodytes (Chimpanzee)
gi|243898 - gi|243898|gb|AAB21194.1| GOR [Pan]
3.0E-68 [109..395] [2..299]
gi|24650714, gi|... - gi|7301627|gb|AAF56745.1| CG12877, isoform A [Drosophila melanogaster], gi|24650714|ref|NP_651584.1|...
1.0E-66 [25..395] [611..1007]
gi|11357754, gi|... - gi|6522931|emb|CAB62118.1| hypothetical protein [Arabidopsis thaliana], gi|15229668|ref|NP_190579.1|...
2.0E-53 [111..404] [7..311]
CE24469 - status:Partially_confirmed UniProt:Q9U220 protein_id:CAB60521.1
6.0E-53 [92..389] [19..332]
DPO3_THEMA - DNA polymerase III polC-type OS=Thermotoga maritima GN=polC PE=1 SV=1
DPO3_THEMA - DNA polymerase III PolC-type OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099...
8.0E-53 [124..403] [235..527]

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Predicted Domain #1
Region A:
Residues: [1-189]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSLLRPVDL VNQPLGFQER YKILQKLFKQ LQKAYAHTKG TNIDLERLAT RLEVHVAKNS  60
   61 LSGQSYKFNM SILLRDVLKY KGDLSKIKIN GRPLKGAKPH LSSIGNANSI TTKSKAMEAL 120
  121 KALILDSKVL EKNGYIVKEM QNKTNDDNST QLYAPCLRCS SNFKKTDIME KTLCRYHPLK 180
  181 RIYNRDTKN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [190-404]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HQYPCCGETT DSVSFLRLGC KTFFHHVFRG ESYDELCKIS KFSSTDDIDG VENVLSLDCE  60
   61 MAFTSLGYEM IRLTIVDFFT GKTLFDHVIQ PIGDIVDLNS DFSGVHEIDR TNCPTYKEAL 120
  121 DVFLSENLIN KNSILIGHGL ENDLNVMRLF HNKVIDTAIL YSRTKFKVSL KNLAFEVLSR 180
  181 KIQNGEHDSS QDAIATMDVV KVKIGISPSQ NKWEK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.69897
Match: 1dpi__
Description: Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle