YRC Public Data Repository - Protein Structure Prediction

Protein:	MEF1
Organism:	Saccharomyces cerevisiae
Length:	761 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MEF1.

Description	E-value	Query Range	Subject Range
gi\|10279668 - gi\|10279668\|emb\|CAC09927.1\| translation elongation factor G, EF-G [Geobacillus stearothermophilus]	0.0	[59..753]	[1..688]
EFG_BACHD - Elongation factor G OS=Bacillus halodurans GN=fusA PE=3 SV=2 EFG_BACHD - Elongation factor G OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 /...	0.0	[59..753]	[1..688]
EFGM_YEAST - Elongation factor G, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MEF1 ... MEF1 - Mitochondrial elongation factor involved in translational elongation	0.0	[1..761]	[1..761]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[59..753]	[1..688]
EFG_HELPJ - Elongation factor G OS=Helicobacter pylori (strain J99 / ATCC 700824) GN=fusA PE=3 SV=3 gi\|7443440 - pir\|\|G71847 translation elongation factor EF-G (ef-g) - Helicobacter pylori (strain J99)	0.0	[59..759]	[1..692]
EFG_HELPY - Elongation factor G OS=Helicobacter pylori GN=fusA PE=3 SV=2 EFG_HELPY - Elongation factor G OS=Helicobacter pylori (strain ATCC 700392 / 26695) GN=fusA PE=3 SV=2	0.0	[59..759]	[1..692]
gi\|16077180, gi\|... - gi\|2632379\|emb\|CAB11888.1\| elongation factor G [Bacillus subtilis subsp. subtilis str. 168], gi\|1607... EFG_BACSU - Elongation factor G OS=Bacillus subtilis GN=fusA PE=1 SV=2	0.0	[59..753]	[1..688]
EFG_CAMJE - Elongation factor G OS=Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11... EFG_CAMJE - Elongation factor G OS=Campylobacter jejuni GN=fusA PE=3 SV=1 gi\|57504744, gi\|... - gi\|57504744\|ref\|ZP_00370798.1\| translation elongation factor G [Campylobacter coli RM2228], gi\|57019... EFG_CAMJ8 - Elongation factor G OS=Campylobacter jejuni subsp. jejuni serotype O:6 (strain 81116 / NCTC 11828) G... gi\|88597042, gi\|... - gi\|88597042\|ref\|ZP_01100278.1\| translation elongation factor G [Campylobacter jejuni subsp. jejuni 8... gi\|86153594, gi\|... - gi\|86153594\|ref\|ZP_01071797.1\| translation elongation factor G [Campylobacter jejuni subsp. jejuni H... gi\|86149091, gi\|... - gi\|86149091\|ref\|ZP_01067323.1\| translation elongation factor G [Campylobacter jejuni subsp. jejuni C... EFG_CAMJR - Elongation factor G OS=Campylobacter jejuni (strain RM1221) GN=fusA PE=3 SV=1	0.0	[59..755]	[1..690]
gi\|6119886 - gi\|6119886\|gb\|AAF04270.1\|AF181877_1 elongation factor G [Helicobacter pylori]	0.0	[71..759]	[1..682]

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Predicted Domain #1

Region A:
Residues: [1-352]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVQKMMWVP RKMVGGRIPF FTCSKVFSGF SRRSFHESPL ARSTYEEEKV LVDEIKQKLT  60
   61 PDDIGRCNKL RNIGISAHID SGKTTFTERV LYYTKRIKAI HEVRGRDNVG AKMDSMDLER 120
  121 EKGITIQSAA TYCSWDKEGK NYHFNLIDTP GHIDFTIEVE RALRVLDGAV LVVCAVSGVQ 180
  181 SQTVTVDRQM RRYNVPRVTF INKMDRMGSD PFRAIEQLNS KLKIPAAAVQ IPIGSESSLS 240
  241 GVVDLINRVA IYNKGDNGEI IEKGPVPENL KPLMEEKRQL LIETLADVDD EMAEMFLEEK 300
  301 EPTTQQIKDA IRRSTIARSF TPVLMGSALA NTGIQPVLDA IVDYLPNPSE VL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	2590.0
Match:	1dar__
Description:	Elongation factor G (EF-G), domain II; Elongation factor G (EF-G), N-terminal (G) domain; Elongation factor G (EF-G), domain IV; Elongation factor G (EF-G)
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [353-498]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTALDVSNNE AKVNLVPAVQ QPFVGLAFKL EEGKYGQLTY VRVYQGRLRK GNYITNVKTG  60
   61 KKVKVARLVR MHSSEMEDVD EVGSGEICAT FGIDCASGDT FTDGSVQYSM SSMYVPDAVV 120
  121 SLSITPNSKD ASNFSKALNR FQKEDP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	2590.0
Match:	1dar__
Description:	Elongation factor G (EF-G), domain II; Elongation factor G (EF-G), N-terminal (G) domain; Elongation factor G (EF-G), domain IV; Elongation factor G (EF-G)
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [499-761]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TFRVKFDPES KETIISGMGE LHLEIYVERM RREYNVDCVT GKPQVSYRES ITIPADFDYT  60
   61 HKKQSGGAGQ YGRVIGTLSP VDDITKGNIF ETAIVGGRIP DKYLAACGKG FEEVCEKGPL 120
  121 IGHRVLDVKM LINDGAIHAV DSNELSFKTA TMSAFRDAFL RAQPVIMEPI MNVSVTSPNE 180
  181 FQGNVIGLLN KLQAVIQDTE NGHDEFTLKA ECALSTMFGF ATSLRASTQG KGEFSLEFSH 240
  241 YAPTAPHVQK ELISEFQKKQ AKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	2590.0
Match:	1dar__
Description:	Elongation factor G (EF-G), domain II; Elongation factor G (EF-G), N-terminal (G) domain; Elongation factor G (EF-G), domain IV; Elongation factor G (EF-G)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits