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View Structure Prediction Details

Protein: YEH2
Organism: Saccharomyces cerevisiae
Length: 538 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YEH2.

Description E-value Query
Range
Subject
Range
YEH1 - Steryl ester hydrolase, one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl este...
YEH1_YEAST - Sterol esterase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YEH1 PE=1 SV=1
417.0 [0..2] [535..3]
gi|1572663 - gi|1572663|gb|AAB09081.1| yolk protein 2 [Galleria mellonella]
391.0 [0..32] [534..19]
gi|149062738, gi... - gi|77917572|ref|NP_036864.3| lipase A [Rattus norvegicus], gi|47938961|gb|AAH72532.1| Lipase A, lyso...
390.0 [0..141] [536..26]
gi|12845477 - gi|12845477|dbj|BAB26766.1| unnamed protein product [Mus musculus]
389.0 [0..143] [532..27]
gi|758064 - gi|758064|emb|CAA29414.1| gastric lipase precursor [Homo sapiens]
389.0 [0..144] [532..23]

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Predicted Domain #1
Region A:
Residues: [1-121]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVNKVVDEVQ RLVSAIILTS FMTGLFILSL WKNYVTVHFQ HKNDPRDTRS SRTKIQPNDK  60
   61 KKKRPARHSR PLSISSTTPL DLQRDQENNI EYDRTVTSKL SMTSNASLSE NGDGNANIKM 120
  121 E

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [122-538]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TNVNQAPYAA ENPFQNIALA EDTKLVPDLK YYYKEYGIDI EEFEVETDDG FIIDLWHFKS  60
   61 RLNDGVEEVK REPILLLHGL LQSCGAFASS GRKSLAYFLY ESGFDVWLGN NRCGLNAKWN 120
  121 MKKLGNDHSK KWDWDMHQMV QYDLKALINY VLDSTGYAKL SLVAHSQGTT QGFMGLVNGE 180
  181 KLYASDFKLV DKLENFVALA PAVYPGPLLD EKAFVRLMAK GIDSPWYFGR RSFIPLMMTM 240
  241 RKLMVGTKIF SFLSYIMFNY LFDWNDVLWD RVLRDRNFLF SPVHISVKLM QWWLSPLPNK 300
  301 LSFKKGAEKI FPDKKTWFPI AKNDDDSGNN LDNNKLHLNP KRQNSEEFPH IIMFIPKQDR 360
  361 LVDGERLINH FINHEANAVY KIWYIDEYSH LDVLWAHDVI DRIGKPMIEN LRFPNAR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 296.758605
Match: 1k8qA
Description: Gastric lipase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle