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View Structure Prediction Details

Protein: PML1
Organism: Saccharomyces cerevisiae
Length: 204 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PML1.

Description E-value Query
Range
Subject
Range
PML1_YEAST - Pre-mRNA leakage protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PML1 PE=1 SV=...
gi|151941184 - gi|151941184|gb|EDN59562.1| Pre-mRNA Leakage [Saccharomyces cerevisiae YJM789]
gi|190406057 - gi|190406057|gb|EDV09324.1| pre-mRNA leakage protein 1 [Saccharomyces cerevisiae RM11-1a]
gi|207343202 - gi|207343202|gb|EDZ70737.1| YLR016Cp-like protein [Saccharomyces cerevisiae AWRI1631]
PML1 - Subunit of the RES complex, which is required for nuclear retention of unspliced pre-mRNAs; acts in ...
6.0E-62 [1..204] [1..204]
DDL_ARATH - FHA domain-containing protein DDL OS=Arabidopsis thaliana GN=DDL PE=1 SV=1
5.0E-35 [28..203] [159..311]
gi|208967428 - gi|208967428|dbj|BAG73728.1| Smad nuclear interacting protein 1 [synthetic construct]
SNIP1 - Smad nuclear interacting protein 1
7.0E-30 [28..202] [222..372]
CE08529 - status:Confirmed UniProt:P91125 protein_id:AAB42323.1
5.0E-29 [28..189] [129..268]
ODHI_CORGL - Oxoglutarate dehydrogenase inhibitor OS=Corynebacterium glutamicum GN=odhI PE=1 SV=1
gi|145295574, gi... - gi|145295574|ref|YP_001138395.1| hypothetical protein cgR_1501 [Corynebacterium glutamicum R], gi|14...
ODHI_CORGL - Oxoglutarate dehydrogenase inhibitor OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / ...
6.0E-21 [40..193] [13..135]
gi|12060475 - gi|12060475|dbj|BAB20624.1| adenylate cyclase [Thermosynechococcus elongatus]
gi|22299953, gi|... - gi|22299953|ref|NP_683200.1| adenylate cyclase [Thermosynechococcus elongatus BP-1], gi|22296138|dbj...
1.0E-20 [68..194] [61..162]

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Predicted Domain #1
Region A:
Residues: [1-72]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFHRRKRPYN TRNYGHDDKK FKSQYIDIMP DFSPSGLLEL ESNNKEGIAL KHVEPQDAIS  60
   61 PDNYMDMLGL EA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.715 0.027 cytoplasm d.58.7 RNA-binding domain, RBD
View Download 0.783 0.027 cytoplasm d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.802 0.027 cytoplasm d.58.17 Metal-binding domain
View Download 0.651 0.027 cytoplasm d.74.2 C-terminal domain of arginine repressor
View Download 0.665 0.027 cytoplasm d.52.1 Alpha-lytic protease prodomain
View Download 0.635 0.027 cytoplasm d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.618 0.027 cytoplasm d.58.12 eEF-1beta-like
View Download 0.618 0.027 cytoplasm d.57.1 DNA damage-inducible protein DinI
View Download 0.614 0.027 cytoplasm d.57.1 DNA damage-inducible protein DinI
View Download 0.589 0.027 cytoplasm d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.561 0.027 cytoplasm d.74.5 Hypothetical protein Yml108w
View Download 0.553 0.027 cytoplasm d.58.12 eEF-1beta-like
View Download 0.532 0.027 cytoplasm d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.528 0.027 cytoplasm d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.513 0.027 cytoplasm d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.508 0.027 cytoplasm d.58.17 Metal-binding domain
View Download 0.503 0.027 cytoplasm d.57.1 DNA damage-inducible protein DinI
View Download 0.503 0.027 cytoplasm d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.499 0.027 cytoplasm d.58.17 Metal-binding domain
View Download 0.497 0.027 cytoplasm d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.491 0.027 cytoplasm d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.483 0.027 cytoplasm d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.481 0.027 cytoplasm d.58.17 Metal-binding domain
View Download 0.474 0.027 cytoplasm d.58.43 Mechanosensitive channel protein MscS (YggB), C-terminal domain
View Download 0.472 0.027 cytoplasm d.58.5 GlnB-like
View Download 0.466 0.027 cytoplasm d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.451 0.027 cytoplasm d.58.17 Metal-binding domain
View Download 0.449 0.027 cytoplasm d.58.3 Protease propeptides/inhibitors
View Download 0.449 0.027 cytoplasm d.74.5 Hypothetical protein Yml108w
View Download 0.444 0.027 cytoplasm d.58.10 Acylphosphatase-like
View Download 0.440 0.027 cytoplasm d.12.1 Ribosomal proteins L23 and L15e
View Download 0.434 0.027 cytoplasm d.58.43 Mechanosensitive channel protein MscS (YggB), C-terminal domain
View Download 0.433 0.027 cytoplasm d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.431 0.027 cytoplasm d.52.1 Alpha-lytic protease prodomain
View Download 0.430 0.027 cytoplasm d.58.17 Metal-binding domain
View Download 0.416 0.027 cytoplasm d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.415 0.027 cytoplasm d.58.17 Metal-binding domain
View Download 0.414 0.027 cytoplasm d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.400 0.027 cytoplasm d.39.1 Dynein light chain 8 (DLC8)
View Download 0.398 0.027 cytoplasm d.74.3 RBP11-like subunits of RNA polymerase
View Download 0.393 0.027 cytoplasm d.58.10 Acylphosphatase-like
View Download 0.390 0.027 cytoplasm d.58.17 Metal-binding domain
View Download 0.390 0.027 cytoplasm d.58.12 eEF-1beta-like
View Download 0.387 0.027 cytoplasm b.49.1 N-terminal domain of alpha and beta subunits of F1 ATP synthase
View Download 0.379 0.027 cytoplasm d.52.4 YhbC-like, N-terminal domain
View Download 0.377 0.027 cytoplasm d.74.5 Hypothetical protein Yml108w
View Download 0.376 0.027 cytoplasm d.58.17 Metal-binding domain
View Download 0.373 0.027 cytoplasm d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.369 0.027 cytoplasm d.52.5 Probable GTPase Der, C-terminal domain
View Download 0.368 0.027 cytoplasm d.74.2 C-terminal domain of arginine repressor
View Download 0.356 0.027 cytoplasm d.57.1 DNA damage-inducible protein DinI
View Download 0.354 0.027 cytoplasm d.206.1 YggU-like
View Download 0.353 0.027 cytoplasm d.52.1 Alpha-lytic protease prodomain
View Download 0.350 0.027 cytoplasm d.58.7 RNA-binding domain, RBD
View Download 0.346 0.027 cytoplasm g.3.11 EGF/Laminin
View Download 0.346 0.027 cytoplasm d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.344 0.027 cytoplasm d.206.1 YggU-like
View Download 0.344 0.027 cytoplasm d.58.10 Acylphosphatase-like
View Download 0.338 0.027 cytoplasm d.58.17 Metal-binding domain
View Download 0.338 0.027 cytoplasm d.58.11 EF-G/eEF-2 domains III and V
View Download 0.337 0.027 cytoplasm d.58.17 Metal-binding domain
View Download 0.336 0.027 cytoplasm d.58.7 RNA-binding domain, RBD
View Download 0.335 0.027 cytoplasm d.58.5 GlnB-like
View Download 0.334 0.027 cytoplasm d.58.35 Pseudouridine synthase
View Download 0.333 0.027 cytoplasm d.52.1 Alpha-lytic protease prodomain
View Download 0.329 0.027 cytoplasm d.58.26 GHMP Kinase, C-terminal domain
View Download 0.328 0.027 cytoplasm d.58.8 Viral DNA-binding domain
View Download 0.328 0.027 cytoplasm d.58.36 Sulfite reductase, domains 1 and 3
View Download 0.325 0.027 cytoplasm d.52.1 Alpha-lytic protease prodomain
View Download 0.324 0.027 cytoplasm d.52.1 Alpha-lytic protease prodomain
View Download 0.319 0.027 cytoplasm d.58.40 D-ribose-5-phosphate isomerase (RpiA), lid domain
View Download 0.318 0.027 cytoplasm d.58.23 Probable ACP-binding domain of malonyl-CoA ACP transacylase
View Download 0.316 0.027 cytoplasm d.58.7 RNA-binding domain, RBD
View Download 0.316 0.027 cytoplasm d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.312 0.027 cytoplasm d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.312 0.027 cytoplasm d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.311 0.027 cytoplasm d.129.1 TATA-box binding protein-like
View Download 0.310 0.027 cytoplasm d.58.8 Viral DNA-binding domain
View Download 0.309 0.027 cytoplasm d.74.3 RBP11-like subunits of RNA polymerase
View Download 0.306 0.027 cytoplasm d.52.3 Prokaryotic type KH domain (KH-domain type II)
View Download 0.305 0.027 cytoplasm d.58.40 D-ribose-5-phosphate isomerase (RpiA), lid domain
View Download 0.303 0.027 cytoplasm d.58.12 eEF-1beta-like
View Download 0.302 0.027 cytoplasm d.74.5 Hypothetical protein Yml108w
View Download 0.298 0.027 cytoplasm d.58.42 N-utilization substance G protein NusG, N-terminal domain
View Download 0.297 0.027 cytoplasm d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.296 0.027 cytoplasm d.58.24 CheY-binding domain of CheA
View Download 0.294 0.027 cytoplasm d.58.10 Acylphosphatase-like
View Download 0.291 0.027 cytoplasm d.58.23 Probable ACP-binding domain of malonyl-CoA ACP transacylase
View Download 0.288 0.027 cytoplasm d.58.23 Probable ACP-binding domain of malonyl-CoA ACP transacylase
View Download 0.287 0.027 cytoplasm d.141.1 Ribosomal protein L6
View Download 0.285 0.027 cytoplasm d.57.1 DNA damage-inducible protein DinI
View Download 0.281 0.027 cytoplasm d.58.3 Protease propeptides/inhibitors
View Download 0.279 0.027 cytoplasm d.74.2 C-terminal domain of arginine repressor
View Download 0.278 0.027 cytoplasm d.141.1 Ribosomal protein L6
View Download 0.276 0.027 cytoplasm d.58.43 Mechanosensitive channel protein MscS (YggB), C-terminal domain
View Download 0.274 0.027 cytoplasm b.34.5 Translation proteins SH3-like domain
View Download 0.269 0.027 cytoplasm d.57.1 DNA damage-inducible protein DinI
View Download 0.269 0.027 cytoplasm d.58.40 D-ribose-5-phosphate isomerase (RpiA), lid domain
View Download 0.269 0.027 cytoplasm d.58.40 D-ribose-5-phosphate isomerase (RpiA), lid domain
View Download 0.268 0.027 cytoplasm d.214.1 Hypothetical protein MTH1880
View Download 0.268 0.027 cytoplasm d.58.5 GlnB-like
View Download 0.268 0.027 cytoplasm d.129.2 Phosphoglucomutase, C-terminal domain
View Download 0.267 0.027 cytoplasm d.58.23 Probable ACP-binding domain of malonyl-CoA ACP transacylase
View Download 0.267 0.027 cytoplasm d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.266 0.027 cytoplasm d.74.1 Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH)
View Download 0.265 0.027 cytoplasm d.58.7 RNA-binding domain, RBD
View Download 0.262 0.027 cytoplasm d.58.3 Protease propeptides/inhibitors
View Download 0.261 0.027 cytoplasm d.58.17 Metal-binding domain
View Download 0.260 0.027 cytoplasm d.58.14 Ribosomal protein S6
View Download 0.259 0.027 cytoplasm d.58.11 EF-G/eEF-2 domains III and V
View Download 0.258 0.027 cytoplasm d.201.1 SRP19
View Download 0.257 0.027 cytoplasm d.58.17 Metal-binding domain
View Download 0.256 0.027 cytoplasm d.201.1 SRP19
View Download 0.254 0.027 cytoplasm d.52.2 GMP synthetase C-terminal dimerisation domain
View Download 0.252 0.027 cytoplasm d.57.1 DNA damage-inducible protein DinI
View Download 0.251 0.027 cytoplasm d.58.1 4Fe-4S ferredoxins
View Download 0.251 0.027 cytoplasm a.77.1 DEATH domain
View Download 0.251 0.027 cytoplasm g.3.7 Scorpion toxin-like
View Download 0.248 0.027 cytoplasm d.58.3 Protease propeptides/inhibitors
View Download 0.248 0.027 cytoplasm d.58.42 N-utilization substance G protein NusG, N-terminal domain
View Download 0.247 0.027 cytoplasm d.9.2 Description not found.
View Download 0.246 0.027 cytoplasm d.206.1 YggU-like
View Download 0.246 0.027 cytoplasm d.58.7 RNA-binding domain, RBD
View Download 0.243 0.027 cytoplasm d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.243 0.027 cytoplasm d.212.1 TolA/TonB C-terminal domain
View Download 0.243 0.027 cytoplasm d.52.3 Prokaryotic type KH domain (KH-domain type II)
View Download 0.241 0.027 cytoplasm d.52.5 Probable GTPase Der, C-terminal domain
View Download 0.237 0.027 cytoplasm d.52.6 BolA-like
View Download 0.236 0.027 cytoplasm d.52.5 Probable GTPase Der, C-terminal domain
View Download 0.236 0.027 cytoplasm d.74.2 C-terminal domain of arginine repressor
View Download 0.235 0.027 cytoplasm d.58.23 Probable ACP-binding domain of malonyl-CoA ACP transacylase
View Download 0.232 0.027 cytoplasm d.58.12 eEF-1beta-like
View Download 0.231 0.027 cytoplasm d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.228 0.027 cytoplasm d.58.10 Acylphosphatase-like
View Download 0.227 0.027 cytoplasm d.58.7 RNA-binding domain, RBD
View Download 0.223 0.027 cytoplasm d.57.1 DNA damage-inducible protein DinI
View Download 0.223 0.027 cytoplasm d.52.3 Prokaryotic type KH domain (KH-domain type II)
View Download 0.222 0.027 cytoplasm d.201.1 SRP19
View Download 0.219 0.027 cytoplasm d.58.17 Metal-binding domain
View Download 0.217 0.027 cytoplasm d.58.1 4Fe-4S ferredoxins
View Download 0.216 0.027 cytoplasm d.58.12 eEF-1beta-like
View Download 0.215 0.027 cytoplasm b.1.2 Fibronectin type III
View Download 0.214 0.027 cytoplasm d.15.7 Immunoglobulin-binding domains
View Download 0.214 0.027 cytoplasm d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.214 0.027 cytoplasm d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.213 0.027 cytoplasm d.12.1 Ribosomal proteins L23 and L15e
View Download 0.213 0.027 cytoplasm d.58.43 Mechanosensitive channel protein MscS (YggB), C-terminal domain
View Download 0.212 0.027 cytoplasm d.58.36 Sulfite reductase, domains 1 and 3
View Download 0.211 0.027 cytoplasm d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.210 0.027 cytoplasm d.58.36 Sulfite reductase, domains 1 and 3
View Download 0.209 0.027 cytoplasm d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.209 0.027 cytoplasm b.1.1 Immunoglobulin
View Download 0.209 0.027 cytoplasm d.58.36 Sulfite reductase, domains 1 and 3
View Download 0.208 0.027 cytoplasm d.58.43 Mechanosensitive channel protein MscS (YggB), C-terminal domain
View Download 0.208 0.027 cytoplasm d.58.43 Mechanosensitive channel protein MscS (YggB), C-terminal domain
View Download 0.208 0.027 cytoplasm a.64.1 Saposin
View Download 0.207 0.027 cytoplasm d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.207 0.027 cytoplasm d.74.5 Hypothetical protein Yml108w
View Download 0.205 0.027 cytoplasm d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.203 0.027 cytoplasm g.3.7 Scorpion toxin-like
View Download 0.202 0.027 cytoplasm d.58.11 EF-G/eEF-2 domains III and V
View Download 0.202 0.027 cytoplasm g.3.7 Scorpion toxin-like
View Download 0.201 0.027 cytoplasm d.52.1 Alpha-lytic protease prodomain
View Download 0.201 0.027 cytoplasm d.52.6 BolA-like
View Download 0.201 0.027 cytoplasm d.74.3 RBP11-like subunits of RNA polymerase
View Download 0.200 0.027 cytoplasm d.52.3 Prokaryotic type KH domain (KH-domain type II)

Predicted Domain #2
Region A:
Residues: [73-204]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RDRTMYELVI YRKNDKDKGP WKRYDLNGRS CYLVGRELGH SLDTDLDDRT EIVVADIGIP  60
   61 EETSSKQHCV IQFRNVRGIL KCYVMDLDSS NGTCLNNVVI PGARYIELRS GDVLTLSEFE 120
  121 EDNDYELIFM NV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.221849
Match: 1lgqA_
Description: Cell cycle checkpoint protein Chfr
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle