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View Structure Prediction Details

Protein: HSP104
Organism: Saccharomyces cerevisiae
Length: 908 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HSP104.

Description E-value Query
Range
Subject
Range
gi|25289928 - pir||AF3276 ATP-dependent clp proteinase, ATP-binding chain clpb BMEI0195 [imported] - Brucella meli...
gi|17986479, gi|... - gi|17986479|ref|NP_539113.1| ATP-dependent Clp protease, ATP-binding subunit CLPB [Brucella melitens...
0.0 [1..880] [57..931]
gi|15803116, gi|... - gi|15803116|ref|NP_289147.1| protein disaggregation chaperone [Escherichia coli O157:H7 EDL933], gi|...
gi|227834799, gi... - gi|227888159|ref|ZP_04005964.1| endopeptidase Clp [Escherichia coli 83972], gi|227834799|gb|EEJ45265...
gi|226839293, gi... - gi|254037669|ref|ZP_04871727.1| heat shock protein [Escherichia sp. 1_1_43], gi|226839293|gb|EEH7131...
gi|26109361, gi|... - gi|26248955|ref|NP_754995.1| protein disaggregation chaperone [Escherichia coli CFT073], gi|26109361...
gi|209762704, gi... - gi|25289895|pir||E85905 heat shock protein [imported] - Escherichia coli (strain O157:H7, substrain ...
0.0 [1..865] [4..858]
CLPB_SALTY - Chaperone protein ClpB OS=Salmonella typhimurium GN=clpB PE=3 SV=1
CLPB_SALTY - Chaperone protein clpB OS=Salmonella typhimurium GN=clpB PE=3 SV=1
CLPB_SALTI - Chaperone protein clpB OS=Salmonella typhi GN=clpB PE=3 SV=1
gi|213850142 - gi|213850142|ref|ZP_03381040.1| protein disaggregation chaperone [Salmonella enterica subsp. enteric...
gi|213999720 - gi|213999720|ref|ZP_03410455.1| protein disaggregation chaperone [Salmonella enterica subsp. enteric...
gi|194448814, gi... - gi|194448814|ref|YP_002046666.1| protein disaggregation chaperone [Salmonella enterica subsp. enteri...
gi|197244024, gi... - gi|197265769|ref|ZP_03165843.1| ATP-dependent chaperone protein ClpB [Salmonella enterica subsp. ent...
gi|213051813 - gi|213051813|ref|ZP_03344691.1| protein disaggregation chaperone [Salmonella enterica subsp. enteric...
lcl|NC_016856.1_... - [gene=clpB] [protein=protein disaggregation chaperone] [protein_id=YP_005238782.1] [location=complem...
gi|213649749 - gi|213649749|ref|ZP_03379802.1| protein disaggregation chaperone [Salmonella enterica subsp. enteric...
gi|29142985, gi|... - gi|29142985|ref|NP_806327.1| protein disaggregation chaperone [Salmonella enterica subsp. enterica s...
gi|16761514 - gi|16761514|ref|NP_457131.1| protein disaggregation chaperone [Salmonella enterica subsp. enterica s...
CLPB_SALTI - Chaperone protein ClpB OS=Salmonella typhi GN=clpB PE=3 SV=1
gi|205329269, gi... - gi|205329269|gb|EDZ16033.1| chaperone protein clpB [Salmonella enterica subsp. enterica serovar 4,[5...
CLPB_SALTY - Chaperone protein ClpB OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=clpB PE=3 ...
gi|168244680, gi... - gi|205336469|gb|EDZ23233.1| chaperone protein clpB [Salmonella enterica subsp. enterica serovar Heid...
0.0 [2..865] [1..854]
gi|188487823, gi... - gi|75513198|ref|ZP_00735640.1| COG0542: ATPases with chaperone activity, ATP-binding subunit [Escher...
gi|74313151, gi|... - gi|74313151|ref|YP_311570.1| protein disaggregation chaperone [Shigella sonnei Ss046], gi|73856628|g...
gi|75236016, gi|... - gi|75236016|ref|ZP_00720150.1| COG0542: ATPases with chaperone activity, ATP-binding subunit [Escher...
gi|193064051, gi... - gi|75258013|ref|ZP_00729487.1| COG0542: ATPases with chaperone activity, ATP-binding subunit [Escher...
gi|81246456, gi|... - gi|82545045|ref|YP_408992.1| protein disaggregation chaperone [Shigella boydii Sb227], gi|81246456|g...
gi|83585276, gi|... - gi|83585276|ref|ZP_00923925.1| COG0542: ATPases with chaperone activity, ATP-binding subunit [Escher...
gi|189354548, gi... - gi|189354548|gb|EDU72967.1| ATP-dependent chaperone ClpB [Escherichia coli O157:H7 str. EC4401], gi|...
gi|157080262, gi... - gi|75187341|ref|ZP_00700608.1| COG0542: ATPases with chaperone activity, ATP-binding subunit [Escher...
gi|189367288, gi... - gi|189367288|gb|EDU85704.1| ATP-dependent chaperone ClpB [Escherichia coli O157:H7 str. EC4501], gi|...
gi|168771698, gi... - gi|189359601|gb|EDU78020.1| ATP-dependent chaperone ClpB [Escherichia coli O157:H7 str. EC4486], gi|...
gi|187770676, gi... - gi|187770676|gb|EDU34520.1| ATP-dependent chaperone ClpB [Escherichia coli O157:H7 str. EC4196], gi|...
gi|75214716 - gi|75214716|ref|ZP_00713224.1| COG0542: ATPases with chaperone activity, ATP-binding subunit [Escher...
gi|189003333, gi... - gi|189003333|gb|EDU72319.1| ATP-dependent chaperone ClpB [Escherichia coli O157:H7 str. EC4076], gi|...
gi|75227675, gi|... - gi|75227675|ref|ZP_00714416.1| COG0542: ATPases with chaperone activity, ATP-binding subunit [Escher...
gi|189370894, gi... - gi|189370894|gb|EDU89310.1| ATP-dependent chaperone ClpB [Escherichia coli O157:H7 str. EC869], gi|1...
gi|157067748, gi... - gi|75196607|ref|ZP_00706677.1| COG0542: ATPases with chaperone activity, ATP-binding subunit [Escher...
gi|168801710, gi... - gi|189376181|gb|EDU94597.1| ATP-dependent chaperone ClpB [Escherichia coli O157:H7 str. EC508], gi|1...
gi|194411789, gi... - gi|75208572|ref|ZP_00708885.1| COG0542: ATPases with chaperone activity, ATP-binding subunit [Escher...
gi|170019129, gi... - gi|170019129|ref|YP_001724083.1| protein disaggregation chaperone [Escherichia coli ATCC 8739], gi|1...
gi|254593940, gi... - gi|254794540|ref|YP_003079377.1| protein disaggregation chaperone [Escherichia coli O157:H7 str. TW1...
gi|253974464, gi... - gi|254162563|ref|YP_003045671.1| protein disaggregation chaperone [Escherichia coli B str. REL606], ...
gi|254289324, gi... - gi|254289324|ref|YP_003055072.1| protein disaggregation chaperone [Escherichia coli BL21(DE3)], gi|2...
gi|251785915, gi... - gi|251785915|ref|YP_003000219.1| hypothetical protein B21_02446 [Escherichia coli BL21], gi|24237818...
gi|238901753, gi... - gi|238901753|ref|YP_002927549.1| protein disaggregation chaperone [Escherichia coli BW2952], gi|2388...
gi|188014008, gi... - gi|188014008|gb|EDU52130.1| ATP-dependent chaperone ClpB [Escherichia coli O157:H7 str. EC4113], gi|...
EG10157 - protein disaggregation chaperone / Bichaperone with DnaK for protein disaggregation; disaggregase; p...
CLPB_ECOLI - Chaperone clpB (Heat-shock protein F84.1) - Escherichia coli
CLPB_ECOL6 - Chaperone protein ClpB OS=Escherichia coli O6 GN=clpB PE=3 SV=1
gi|89109394, gi|... - gi|89109394|ref|AP_003174.1| protein disaggregation chaperone [Escherichia coli str. K-12 substr. W3...
gi|13362926, gi|... - gi|15832709|ref|NP_311482.1| protein disaggregation chaperone [Escherichia coli O157:H7 str. Sakai],...
gi|110642755, gi... - gi|110642755|ref|YP_670485.1| protein disaggregation chaperone [Escherichia coli 536], gi|110344347|...
CLPB_ECO57 - Chaperone protein ClpB OS=Escherichia coli O157:H7 GN=clpB PE=3 SV=1
EG10157 - protein disaggregation chaperone / Bichaperone with DnaK for protein disaggregation; disaggregase; p...
gi|215266003, gi... - gi|215487931|ref|YP_002330362.1| protein disaggregation chaperone [Escherichia coli O127:H6 str. E23...
gi|217326744, gi... - gi|217326744|ref|ZP_03442827.1| ATP-dependent chaperone ClpB [Escherichia coli O157:H7 str. TW14588]...
gi|218361940, gi... - gi|218555172|ref|YP_002388085.1| protein disaggregation chaperone [Escherichia coli IAI1], gi|218361...
gi|218428275, gi... - gi|218690711|ref|YP_002398923.1| protein disaggregation chaperone [Escherichia coli ED1a], gi|218428...
gi|218696217, gi... - gi|218696217|ref|YP_002403884.1| protein disaggregation chaperone [Escherichia coli 55989], gi|21835...
gi|218371090, gi... - gi|218701104|ref|YP_002408733.1| protein disaggregation chaperone [Escherichia coli IAI39], gi|21837...
gi|218433191, gi... - gi|218706094|ref|YP_002413613.1| protein disaggregation chaperone [Escherichia coli UMN026], gi|2184...
gi|169890032, gi... - gi|170082197|ref|YP_001731517.1| protein disaggregation chaperone [Escherichia coli str. K-12 substr...
gi|170683980, gi... - gi|170683980|ref|YP_001744777.1| ATP-dependent chaperone protein ClpB [Escherichia coli SMS-3-5], gi...
gi|195940187 - gi|195940187|ref|ZP_03085569.1| protein disaggregation chaperone [Escherichia coli O157:H7 str. EC40...
gi|208805997, gi... - gi|208805997|ref|ZP_03248334.1| ATP-dependent chaperone ClpB [Escherichia coli O157:H7 str. EC4206],...
gi|208813052, gi... - gi|208813052|ref|ZP_03254381.1| ATP-dependent chaperone ClpB [Escherichia coli O157:H7 str. EC4045],...
gi|124500885, gi... - gi|124527993|ref|ZP_01699346.1| ATPase AAA-2 domain protein [Escherichia coli B], gi|124500885|gb|EA...
gi|208819305, gi... - gi|208819305|ref|ZP_03259625.1| ATP-dependent chaperone ClpB [Escherichia coli O157:H7 str. EC4042],...
gi|209397795, gi... - gi|209397795|ref|YP_002272065.1| ATP-dependent chaperone ClpB [Escherichia coli O157:H7 str. EC4115]...
gi|209920069, gi... - gi|209920069|ref|YP_002294153.1| protein disaggregation chaperone [Escherichia coli SE11], gi|209913...
CLPB_ECOL6 - Chaperone protein ClpB OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=clpB PE=3 S...
0.0 [2..865] [1..854]
gi|147365 - gi|147365|gb|AAA24422.1| ATP-dependent protease binding subunit [Escherichia coli]
0.0 [2..865] [1..854]
gi|25289923 - pir||F98216 endopeptidase clp ATP-binding chain B [imported] - Agrobacterium tumefaciens (strain C58...
gi|15890799, gi|... - gi|15890799|ref|NP_356471.1| hypothetical protein AGR_L_1346 [Agrobacterium tumefaciens str. C58], g...
0.0 [2..880] [14..884]
CLPB_YERPE - Chaperone protein ClpB OS=Yersinia pestis GN=clpB PE=3 SV=2
gi|16123432, gi|... - gi|218930300|ref|YP_002348175.1| protein disaggregation chaperone [Yersinia pestis CO92], gi|1612343...
0.0 [2..867] [1..856]
CLPB_PASMU - Chaperone protein clpB OS=Pasteurella multocida GN=clpB PE=3 SV=1
CLPB_PASMU - Chaperone protein ClpB OS=Pasteurella multocida (strain Pm70) GN=clpB PE=3 SV=1
0.0 [2..863] [1..850]
CLPB_BRUSU - Chaperone protein ClpB OS=Brucella suis biovar 1 (strain 1330) GN=clpB PE=2 SV=1
CLPB_BRUSU - Chaperone protein clpB OS=Brucella suis GN=clpB PE=2 SV=1
0.0 [2..880] [1..874]

Back

Predicted Domain #1
Region A:
Residues: [1-85]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNDQTQFTER ALTILTLAQK LASDHQHPQL QPIHILAAFI ETPEDGSVPY LQNLIEKGRY  60
   61 DYDLFKKVVN RNLVRIPQQQ PAPAE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.971 0.127 nucleus a.74.1 Cyclin-like
View Download 0.811 0.025 response to stress a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.951 N/A N/A a.74.1 Cyclin-like
View Download 0.898 N/A N/A a.74.1 Cyclin-like
View Download 0.776 N/A N/A a.74.1 Cyclin-like
View Download 0.773 N/A N/A a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.745 N/A N/A a.60.8 HRDC-like
View Download 0.707 N/A N/A a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.659 N/A N/A a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.638 N/A N/A a.4.1 Homeodomain-like
View Download 0.636 N/A N/A a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.634 N/A N/A a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.631 N/A N/A a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.631 N/A N/A a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.622 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.612 N/A N/A a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.571 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.560 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.548 N/A N/A a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.544 N/A N/A a.4.1 Homeodomain-like
View Download 0.540 N/A N/A a.4.1 Homeodomain-like
View Download 0.539 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.538 N/A N/A a.39.1 EF-hand
View Download 0.530 N/A N/A a.3.1 Cytochrome c
View Download 0.527 N/A N/A a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.521 N/A N/A a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.519 N/A N/A a.3.1 Cytochrome c
View Download 0.516 N/A N/A a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.513 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.513 N/A N/A a.4.1 Homeodomain-like
View Download 0.508 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.505 N/A N/A a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.497 N/A N/A a.4.1 Homeodomain-like
View Download 0.496 N/A N/A a.36.1 Signal peptide-binding domain
View Download 0.493 N/A N/A d.203.1 DsrC, the gamma subunit of dissimilatory sulfite reductase
View Download 0.493 N/A N/A a.74.1 Cyclin-like
View Download 0.486 N/A N/A a.74.1 Cyclin-like
View Download 0.479 N/A N/A a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.470 N/A N/A a.85.1 Hemocyanin, N-terminal domain
View Download 0.465 N/A N/A a.77.1 DEATH domain
View Download 0.464 N/A N/A d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.464 N/A N/A a.74.1 Cyclin-like
View Download 0.460 N/A N/A a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.457 N/A N/A a.36.1 Signal peptide-binding domain
View Download 0.456 N/A N/A a.4.1 Homeodomain-like
View Download 0.451 N/A N/A a.4.1 Homeodomain-like
View Download 0.450 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.442 N/A N/A a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.431 N/A N/A a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.425 N/A N/A a.60.4 DNA repair protein Rad51, N-terminal domain
View Download 0.417 N/A N/A a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.415 N/A N/A d.54.1 Enolase N-terminal domain-like
View Download 0.413 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.412 N/A N/A a.61.1 Retroviral matrix proteins
View Download 0.408 N/A N/A a.64.1 Saposin
View Download 0.399 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.397 N/A N/A d.39.1 Dynein light chain 8 (DLC8)
View Download 0.396 N/A N/A a.74.1 Cyclin-like
View Download 0.395 N/A N/A a.74.1 Cyclin-like
View Download 0.391 N/A N/A a.46.1 Methionine synthase domain
View Download 0.388 N/A N/A a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.387 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.384 N/A N/A a.156.1 S13-like H2TH domain
View Download 0.383 N/A N/A a.65.1 Annexin
View Download 0.380 N/A N/A a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.373 N/A N/A a.4.12 TrpR-like
View Download 0.365 N/A N/A a.74.1 Cyclin-like
View Download 0.364 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.364 N/A N/A a.74.1 Cyclin-like
View Download 0.364 N/A N/A a.4.1 Homeodomain-like
View Download 0.363 N/A N/A a.112.1 Description not found.
View Download 0.362 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.361 N/A N/A a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.361 N/A N/A a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.355 N/A N/A d.87.2 CO dehydrogenase flavoprotein C-terminal domain-like
View Download 0.354 N/A N/A a.1.1 Globin-like
View Download 0.352 N/A N/A a.156.1 S13-like H2TH domain
View Download 0.351 N/A N/A a.60.1 SAM/Pointed domain
View Download 0.348 N/A N/A a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.347 N/A N/A a.4.12 TrpR-like
View Download 0.342 N/A N/A a.60.2 RuvA domain 2-like
View Download 0.342 N/A N/A a.3.1 Cytochrome c
View Download 0.335 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.334 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.332 N/A N/A a.4.3 ARID-like
View Download 0.331 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.329 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.328 N/A N/A a.64.1 Saposin
View Download 0.325 N/A N/A a.4.1 Homeodomain-like
View Download 0.324 N/A N/A a.74.1 Cyclin-like
View Download 0.323 N/A N/A a.4.3 ARID-like
View Download 0.323 N/A N/A a.4.1 Homeodomain-like
View Download 0.318 N/A N/A d.66.1 Alpha-L RNA-binding motif
View Download 0.318 N/A N/A d.39.1 Dynein light chain 8 (DLC8)
View Download 0.317 N/A N/A d.58.43 Mechanosensitive channel protein MscS (YggB), C-terminal domain
View Download 0.316 N/A N/A a.158.1 F-box domain
View Download 0.316 N/A N/A a.64.1 Saposin
View Download 0.313 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.312 N/A N/A a.4.1 Homeodomain-like
View Download 0.311 N/A N/A a.4.1 Homeodomain-like
View Download 0.306 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.302 N/A N/A a.74.1 Cyclin-like
View Download 0.301 N/A N/A d.67.2 Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
View Download 0.300 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.299 N/A N/A a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.298 N/A N/A a.50.1 Anaphylotoxins (complement system)
View Download 0.296 N/A N/A a.28.1 ACP-like
View Download 0.296 N/A N/A a.64.1 Saposin
View Download 0.294 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.293 N/A N/A a.135.1 Tetraspanin
View Download 0.293 N/A N/A a.50.1 Anaphylotoxins (complement system)
View Download 0.293 N/A N/A a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.286 N/A N/A a.60.2 RuvA domain 2-like
View Download 0.285 N/A N/A a.77.1 DEATH domain
View Download 0.284 N/A N/A a.36.1 Signal peptide-binding domain
View Download 0.284 N/A N/A a.60.1 SAM/Pointed domain
View Download 0.283 N/A N/A a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.282 N/A N/A a.3.1 Cytochrome c
View Download 0.282 N/A N/A a.74.1 Cyclin-like
View Download 0.280 N/A N/A a.142.1 PTS-regulatory domain, PRD
View Download 0.278 N/A N/A a.4.1 Homeodomain-like
View Download 0.275 N/A N/A a.165.1 Myosin phosphatase inhibitor 17kDa protein, CPI-17
View Download 0.274 N/A N/A a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.274 N/A N/A a.60.1 SAM/Pointed domain
View Download 0.273 N/A N/A a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.273 N/A N/A a.24.17 Group V grass pollen allergen
View Download 0.272 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.271 N/A N/A a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.271 N/A N/A a.3.1 Cytochrome c
View Download 0.270 N/A N/A a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.268 N/A N/A a.77.1 DEATH domain
View Download 0.266 N/A N/A c.84.1 Phosphoglucomutase, first 3 domains
View Download 0.266 N/A N/A a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.265 N/A N/A a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.264 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.263 N/A N/A d.52.3 Prokaryotic type KH domain (KH-domain type II)
View Download 0.262 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.259 N/A N/A a.77.1 DEATH domain
View Download 0.258 N/A N/A a.112.1 Description not found.
View Download 0.257 N/A N/A a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.257 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.257 N/A N/A d.52.1 Alpha-lytic protease prodomain
View Download 0.256 N/A N/A a.60.11 Hypothetical protein YjbJ
View Download 0.256 N/A N/A a.4.1 Homeodomain-like
View Download 0.255 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.255 N/A N/A a.28.1 ACP-like
View Download 0.254 N/A N/A a.4.1 Homeodomain-like
View Download 0.252 N/A N/A d.188.1 Prokaryotic ribosomal protein L17
View Download 0.252 N/A N/A a.35.1 lambda repressor-like DNA-binding domains
View Download 0.252 N/A N/A a.4.3 ARID-like
View Download 0.251 N/A N/A a.28.1 ACP-like
View Download 0.251 N/A N/A a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.249 N/A N/A a.35.1 lambda repressor-like DNA-binding domains
View Download 0.249 N/A N/A a.36.1 Signal peptide-binding domain
View Download 0.249 N/A N/A a.64.2 Bacteriocin AS-48
View Download 0.247 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.246 N/A N/A a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.245 N/A N/A a.3.1 Cytochrome c
View Download 0.245 N/A N/A a.74.1 Cyclin-like
View Download 0.245 N/A N/A a.81.1 N-terminal domain of DnaB helicase
View Download 0.244 N/A N/A a.4.3 ARID-like
View Download 0.244 N/A N/A a.4.3 ARID-like
View Download 0.243 N/A N/A a.60.11 Hypothetical protein YjbJ
View Download 0.243 N/A N/A a.3.1 Cytochrome c
View Download 0.242 N/A N/A a.60.4 DNA repair protein Rad51, N-terminal domain
View Download 0.241 N/A N/A a.3.1 Cytochrome c
View Download 0.241 N/A N/A a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.241 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.241 N/A N/A a.165.1 Myosin phosphatase inhibitor 17kDa protein, CPI-17
View Download 0.240 N/A N/A a.60.2 RuvA domain 2-like
View Download 0.238 N/A N/A a.21.1 HMG-box
View Download 0.237 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.236 N/A N/A a.64.1 Saposin
View Download 0.236 N/A N/A d.52.7 Ribosome-binding factor A, RbfA
View Download 0.234 N/A N/A a.60.8 HRDC-like
View Download 0.233 N/A N/A d.202.1 Transcription factor NusA, N-terminal domain
View Download 0.233 N/A N/A d.188.1 Prokaryotic ribosomal protein L17
View Download 0.233 N/A N/A a.3.1 Cytochrome c
View Download 0.233 N/A N/A d.68.3 SirA-like
View Download 0.232 N/A N/A a.159.1 Protein serine/threonine phosphatase 2C, C-terminal domain
View Download 0.231 N/A N/A d.58.11 EF-G/eEF-2 domains III and V
View Download 0.231 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.229 N/A N/A a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.229 N/A N/A a.74.1 Cyclin-like
View Download 0.229 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.228 N/A N/A a.60.4 DNA repair protein Rad51, N-terminal domain
View Download 0.227 N/A N/A a.4.1 Homeodomain-like
View Download 0.226 N/A N/A a.60.11 Hypothetical protein YjbJ
View Download 0.225 N/A N/A a.130.1 Chorismate mutase II
View Download 0.224 N/A N/A a.29.2 Bromodomain
View Download 0.224 N/A N/A a.74.1 Cyclin-like
View Download 0.222 N/A N/A a.1.1 Globin-like
View Download 0.221 N/A N/A a.74.1 Cyclin-like
View Download 0.221 N/A N/A a.35.1 lambda repressor-like DNA-binding domains
View Download 0.221 N/A N/A a.5.3 N-terminal domain of phosphatidylinositol transfer protein sec14p
View Download 0.221 N/A N/A a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.221 N/A N/A a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.218 N/A N/A a.1.1 Globin-like
View Download 0.217 N/A N/A a.74.1 Cyclin-like
View Download 0.217 N/A N/A a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.217 N/A N/A a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.216 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.216 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.216 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.216 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.214 N/A N/A a.16.1 S15/NS1 RNA-binding domain
View Download 0.214 N/A N/A a.16.1 S15/NS1 RNA-binding domain
View Download 0.213 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.210 N/A N/A a.4.1 Homeodomain-like
View Download 0.208 N/A N/A a.74.1 Cyclin-like
View Download 0.207 N/A N/A a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.207 N/A N/A d.67.2 Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
View Download 0.206 N/A N/A a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.206 N/A N/A a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.206 N/A N/A a.158.1 F-box domain
View Download 0.205 N/A N/A a.65.1 Annexin
View Download 0.202 N/A N/A a.3.1 Cytochrome c
View Download 0.201 N/A N/A a.60.4 DNA repair protein Rad51, N-terminal domain
View Download 0.201 N/A N/A c.9.1 Barstar (barnase inhibitor)
View Download 0.201 N/A N/A a.39.3 Cloroperoxidase
View Download 0.200 N/A N/A a.60.9 lambda integrase-like, N-terminal domain

Predicted functions:

Term Confidence Notes
transporter activity 3.54081962055485 bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism 3.36181317078971 bayes_pls_golite062009
transmembrane transporter activity 3.29578916194335 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.95079405147356 bayes_pls_golite062009
pyrophosphatase activity 2.87427509025394 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.85499564954033 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.85178667290149 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
hydrolase activity 2.55157966585974 bayes_pls_golite062009
ATPase activity 2.39535714892224 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 2.32451967319952 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 2.20669061476179 bayes_pls_golite062009
ATPase activity, coupled 2.18396165590908 bayes_pls_golite062009
nucleic acid binding 2.11222585187695 bayes_pls_golite062009
DNA binding 1.7904783386531 bayes_pls_golite062009
protein transporter activity 1.71214667007262 bayes_pls_golite062009
transcription regulator activity 1.68903321260301 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.67543589693508 bayes_pls_golite062009
substrate-specific transporter activity 1.29730375126024 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
purine nucleotide binding 0.929901285538132 bayes_pls_golite062009
nucleotide binding 0.922442819194247 bayes_pls_golite062009
purine ribonucleotide binding 0.920987930180051 bayes_pls_golite062009
ribonucleotide binding 0.920926158369519 bayes_pls_golite062009
motor activity 0.87979065815418 bayes_pls_golite062009
structural constituent of ribosome 0.860102064846772 bayes_pls_golite062009
structure-specific DNA binding 0.762584163889896 bayes_pls_golite062009
DNA-dependent ATPase activity 0.75383985982414 bayes_pls_golite062009
guanyl nucleotide binding 0.640772201693186 bayes_pls_golite062009
transcription activator activity 0.638755032892208 bayes_pls_golite062009
guanyl ribonucleotide binding 0.63468044350616 bayes_pls_golite062009
GTP binding 0.621689261700018 bayes_pls_golite062009
transcription factor activity 0.603758349693077 bayes_pls_golite062009
double-stranded DNA binding 0.49000746592281 bayes_pls_golite062009
protein transmembrane transporter activity 0.46552249844591 bayes_pls_golite062009
GTPase activity 0.437665353870877 bayes_pls_golite062009
active transmembrane transporter activity 0.434775387083003 bayes_pls_golite062009
ATP binding 0.41092997612902 bayes_pls_golite062009
adenyl ribonucleotide binding 0.385813421701492 bayes_pls_golite062009
adenyl nucleotide binding 0.377870145186619 bayes_pls_golite062009
ion transmembrane transporter activity 0.355466224802969 bayes_pls_golite062009
helicase activity 0.33971254173831 bayes_pls_golite062009
sequence-specific DNA binding 0.334630071828653 bayes_pls_golite062009
primary active transmembrane transporter activity 0.294474570607914 bayes_pls_golite062009
translation regulator activity 0.29096092258568 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.282352478532746 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.274994961137851 bayes_pls_golite062009
DNA strand annealing activity 0.270268254152179 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.220608508617331 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.219533217661421 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.219157471322311 bayes_pls_golite062009
signal recognition particle binding 0.20866768220789 bayes_pls_golite062009
microtubule motor activity 0.11674780318211 bayes_pls_golite062009
structural molecule activity 0.11239762372728 bayes_pls_golite062009
cation transmembrane transporter activity 0.0254369227200564 bayes_pls_golite062009
ATP-dependent helicase activity 0.0136700590511267 bayes_pls_golite062009
purine NTP-dependent helicase activity 0.0136700590511267 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [86-161]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ITPSYALGKV LQDAAKIQKQ QKDSFIAQDH ILFALFNDSS IQQIFKEAQV DIEAIKQQAL  60
   61 ELRGNTRIDS RGADTN

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 9.366532
Match: PF02861
Description: Clp amino terminal domain

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [162-353]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPLEYLSKYA IDMTEQARQG KLDPVIGREE EIRSTIRVLA RRIKSNPCLI GEPGIGKTAI  60
   61 IEGVAQRIID DDVPTILQGA KLFSLDLAAL TAGAKYKGDF EERFKGVLKE IEESKTLIVL 120
  121 FIDEIHMLMG NGKDDAANIL KPALSRGQLK VIGATTNNEY RSIVEKDGAF ERRFQKIEVA 180
  181 EPSVRQTVAI LR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 679.69897
Match: 1jbkA_
Description: ClpB
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [354-436]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLQPKYEIHH GVRILDSALV TAAQLAKRYL PYRRLPDSAL DLVDISCAGV AVARDSKPEE  60
   61 LDSKERQLQL IQVEIKALER DED

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.02
Match: 1ksfX
Description: N-terminal, ClpS-binding domain of ClpA, an Hsp100 chaperone; ClpA, an Hsp100 chaperone, AAA+ modules
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [437-850]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADSTTKDRLK LARQKEASLQ EELEPLRQRY NEEKHGHEEL TQAKKKLDEL ENKALDAERR  60
   61 YDTATAADLR YFAIPDIKKQ IEKLEDQVAE EERRAGANSM IQNVVDSDTI SETAARLTGI 120
  121 PVKKLSESEN EKLIHMERDL SSEVVGQMDA IKAVSNAVRL SRSGLANPRQ PASFLFLGLS 180
  181 GSGKTELAKK VAGFLFNDED MMIRVDCSEL SEKYAVSKLL GTTAGYVGYD EGGFLTNQLQ 240
  241 YKPYSVLLFD EVEKAHPDVL TVMLQMLDDG RITSGQGKTI DCSNCIVIMT SNLGAEFINS 300
  301 QQGSKIQEST KNLVMGAVRQ HFRPEFLNRI SSIVIFNKLS RKAIHKIVDI RLKEIEERFE 360
  361 QNDKHYKLNL TQEAKDFLAK YGYSDDMGAR PLNRLIQNEI LNKLALRILK NEIK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.0
Match: 1g4aE_
Description: HslU
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [851-908]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DKETVNVVLK KGKSRDENVP EEAEECLEVL PNHEATIGAD TLGDDDNEDS MEIDDDLD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.277 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.216 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.201 a.8.1 Bacterial immunoglobulin/albumin-binding domains


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle