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View Structure Prediction Details

Protein: SPA2
Organism: Saccharomyces cerevisiae
Length: 1466 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPA2.

Description E-value Query
Range
Subject
Range
SPA2_YEAST - Protein SPA2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SPA2 PE=1 SV=1
SPA2 - Component of the polarisome, which functions in actin cytoskeletal organization during polarized gro...
0.0 [1..1466] [1..1466]
gi|24649873, gi|... - gi|7301246|gb|AAF56376.1| CG13648-PA [Drosophila melanogaster], gi|24649873|ref|NP_651318.1| tenecti...
1.0E-57 [103..1364] [1167..2453]
gi|2160784 - gi|2160784|gb|AAB58938.1| myasthenia gravis autoantigen gravin [Homo sapiens]
1.0E-48 [53..1186] [216..1330]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-48 [53..1186] [160..1274]
FP1_MYTCO - Adhesive plaque matrix protein OS=Mytilus coruscus GN=FP1 PE=2 SV=1
4.0E-47 [453..1292] [41..872]
SLP1_CLOTM, SLAP... - (Q06852) Cell surface glycoprotein 1 precursor (Outer layer protein B) (S-layer protein 1), Cell sur...
9.0E-46 [701..1306] [763..1366]

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Predicted Domain #1
Region A:
Residues: [1-284]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGTSSEVSLA HHRDIFHYYV SLKTFFEVTG ENRDRSNSTR AQKARAKLLK LSSSQFYELS  60
   61 TDVSDELQRR IGEDANQPDY LLPKANFHMK RNQARQKLAN LSQTRFNDLL DDILFEIKRR 120
  121 GFDKDLDAPR PPLPQPMKQE VSKDSDDTAR TSTNSSSVTQ VAPNVSVQPS LVIPKMASID 180
  181 WSSEEEEEEQ VKEKPNEPEG KQTSMDEKKE AKPALNPIVT DSDLPDSQVL ARDITSMART 240
  241 PTTTHKNYWD VNDSPIIKVD KDIDNEKGPE QLKSPEVQRA ENNN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [285-373]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNSEMEDKVK ELTDLNSDLH LQIEDLNAKL ASLTSEKEKE KKEEKEEKEK EKNLKINYTI  60
   61 DESFQKELLS LNSQIGELSI ENENLKQKI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [374-959]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEFELHQKKN DNHNDLKITD GFISKYSSAD GLIPAQYILN ANNLIIQFTT RLSAVPIGDS  60
   61 TAISHQIGEE LFQILSQLSN LISQLLLSAD LLQYKDQVIL LKASLSHAIT SIRYFSVYGP 120
  121 VLIPKITVQA AVSEVCFAMC NLIDSAKIKS DSNGESTTSN EGNRQVLEYS SPTATTPMTP 180
  181 TFPSTSGINM KKGFINPRKP ASFLNDVEEE ESPVKPLKIT QKAINSPIIR PSSSNGVPTT 240
  241 SRKPSGTGLF SLMIDSSIAK NSSHKEDNDK YVSPIKAVTS ASNSASSNIS EIPKLTLPPQ 300
  301 AKIGTVIPPS ENQVPNIKIE NTEEDNKRSD ITNEISVKPT SSIADKLKQF EQSSEKKSSP 360
  361 KENPIAKEEM DSKPKLSNKF ITSMNDVSTD DSSSDGNEND DADDDDDFTY MALKQTMKRE 420
  421 GSKIEKNNDS KLPANIVELD LHESPESVKI ESPESIKEIT SSEMSSEMPS SSLPKRLVED 480
  481 VEPSEMPEKG ASVESVRKKN FQEPLGNVES PDMTQKVKSL GMTGKAVGPE SDSRVESPGM 540
  541 TGQIKSLNMA GKVVGPEADS RVESPGMKEQ IKSLGMTGKI TAQESI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [960-1352]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSPEAARKLA SSGEVDKIES PRMVRESESL EAVGNTIPSN MTVKMESPNL KGNTVSEPQE  60
   61 IRRDIASSEP IENVDPPKVL KKIVFPKAVN RTGSPKSVEK TPSSATLKKS GLPEPNSQIV 120
  121 SPELAKNSPL APIKKNVELR ETNKPHTETI TSVEPTNKDA NTSWRDADLN RTIKREEEDE 180
  181 DFDRVNHNIQ ITGAYTKTGK IDYHKIPVDR KAKSEAEVHT SEEDIDESNN VNGKRADAQI 240
  241 HITERKHAFV NPTENSQVKK TSHSPFLNSK PVQYENSESN GGINNHIKIK NTGETTAHDE 300
  301 KHYSDDDDSS YQFVPMKHEE QEQEQNRSEE EESEDDDEEE EDSDFDVDTF DIENPDNTLS 360
  361 ELLLYLEHQT MDVISTIQSL LTSIKKPQVT KGN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [1353-1466]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LRGESNAINQ VIGQMVDATS ISMEQSRNAN LKKHGDWVVQ SLRDCSRRMT ILCQLTGDGI  60
   61 LAKEKSDQDY ADKNFKQRLA GIAFDVAKCT KELVKTVEEA SLKDEINYLN SKLK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.955 i.11.1 Computational models partly based on NMR data

Predicted Domain #6
Region A:
Residues: [825-947]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPESIKEITS SEMSSEMPSS SLPKRLVEDV EPSEMPEKGA SVESVRKKNF QEPLGNVESP  60
   61 DMTQKVKSLG MTGKAVGPES DSRVESPGMT GQIKSLNMAG KVVGPEADSR VESPGMKEQI 120
  121 KSL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [948-1100]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GMTGKITAQE SIKSPEAARK LASSGEVDKI ESPRMVRESE SLEAVGNTIP SNMTVKMESP  60
   61 NLKGNTVSEP QEIRRDIASS EPIENVDPPK VLKKIVFPKA VNRTGSPKSV EKTPSSATLK 120
  121 KSGLPEPNSQ IVSPELAKNS PLAPIKKNVE LRE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1101-1353]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TNKPHTETIT SVEPTNKDAN TSWRDADLNR TIKREEEDED FDRVNHNIQI TGAYTKTGKI  60
   61 DYHKIPVDRK AKSEAEVHTS EEDIDESNNV NGKRADAQIH ITERKHAFVN PTENSQVKKT 120
  121 SHSPFLNSKP VQYENSESNG GINNHIKIKN TGETTAHDEK HYSDDDDSSY QFVPMKHEEQ 180
  181 EQEQNRSEEE ESEDDDEEEE DSDFDVDTFD IENPDNTLSE LLLYLEHQTM DVISTIQSLL 240
  241 TSIKKPQVTK GNL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1354-1466]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RGESNAINQV IGQMVDATSI SMEQSRNANL KKHGDWVVQS LRDCSRRMTI LCQLTGDGIL  60
   61 AKEKSDQDYA DKNFKQRLAG IAFDVAKCTK ELVKTVEEAS LKDEINYLNS KLK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.955 i.11.1 Computational models partly based on NMR data


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle