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View Structure Prediction Details

Protein: ORC3
Organism: Saccharomyces cerevisiae
Length: 616 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ORC3.

Description E-value Query
Range
Subject
Range
gi|190406038 - gi|190406038|gb|EDV09305.1| origin recognition complex subunit [Saccharomyces cerevisiae RM11-1a]
ORC3 - Subunit of the origin recognition complex, which directs DNA replication by binding to replication o...
ORC3_YEAST - Origin recognition complex subunit 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ORC...
gi|207343231 - gi|207343231|gb|EDZ70758.1| YLL004Wp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|151941165 - gi|151941165|gb|EDN59543.1| origin recognition complex subunit [Saccharomyces cerevisiae YJM789]
0.0 [1..616] [1..616]
gi|4049717, gi|9... - gi|9631364|ref|NP_048227.1| ORF MSV156 hypothetical protein [Melanoplus sanguinipes entomopoxvirus],...
0.005 [37..479] [241..668]

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Predicted Domain #1
Region A:
Residues: [1-122]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDLNQSKKM NVSEFADAQR SHYTVYPSLP QSNKNDKHIP FVKLLSGKES EVNVEKRWEL  60
   61 YHQLHSHFHD QVDHIIDNIE ADLKAEISDL LYSETTQKRR CFNTIFLLGS DSTTKIELKD 120
  121 ES

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [123-144]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRYNVLIELT PKESPNVRMM LR

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [156-289]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEEHPTIKYE DINDEDGDFT EQNNDVSYDL SLVENFKRLF GKDLAMVFNF KDVDSINFNT  60
   61 LDNFIILLKS AFKYDHVKIS LIFNINTNLS NIEKNLRQST IRLLKRNYHK LDVSSNKGFK 120
  121 YGNQIFQSFL DTVD

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.56
Match: 1n1bA
Description: (+)-bornyl diphosphate synthase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [145-155]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSMYKLYSAA D

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [290-506]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKLNLSDRFV EFILSKMANN TNHNLQLLTK MLDYSLMSYF FQNAFSVFID PVNVDFLNDD  60
   61 YLKILSRCPT FMFFVEGLIK QHAPADEILS LLTNKNRGLE EFFVEFLVRE NPINGHAKFV 120
  121 ARFLEEELNI TNFNLIELYH NLLIGKLDSY LDRWSACKEY KDRLHFEPID TIFQELFTLD 180
  181 NRSGLLTQSI FPSYKSNIED NLLSWEQVLP SLDKENY

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.56
Match: 1n1bA
Description: (+)-bornyl diphosphate synthase
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [507-616]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTLSGDLDKI MAPVLGQLFK LYREANMTIN IYDFYIAFRE TLPKEEILNF IRKDPSNTKL  60
   61 LELAETPDAF DKVALILFMQ AIFAFENMGL IKFQSTKSYD LVEKCVWRGI 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle