YRC Public Data Repository - Protein Structure Prediction

Protein:	DRE2
Organism:	Saccharomyces cerevisiae
Length:	348 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DRE2.

Description	E-value	Query Range	Subject Range
DRE2 - Protein that may prevent apoptosis by forming a complex with Tah18p in the absence of stress; requir... DRE2_YEAST - Fe-S cluster assembly protein DRE2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DRE2 ... DRE2_YEAS2 - Fe-S cluster assembly protein DRE2 OS=Saccharomyces cerevisiae (strain JAY291) GN=DRE2 PE=3 SV=1	0.0	[1..348]	[1..348]
gi\|190691635, gi... - gi\|190691635\|gb\|ACE87592.1\| cytokine induced apoptosis inhibitor 1 protein [synthetic construct], gi... CIAPIN1 - cytokine induced apoptosis inhibitor 1	2.0E-90	[22..344]	[44..307]
CPIN1_MOUSE - Anamorsin OS=Mus musculus GN=Ciapin1 PE=1 SV=1	5.0E-77	[23..344]	[45..304]
DRE2_SCHPO - Fe-S cluster assembly protein dre2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=dre2 PE... SPBC337.10c - anamorsin family protein	7.0E-41	[211..348]	[145..281]
CE01413 - status:Confirmed UniProt:P41847 protein_id:AAA19060.1	2.0E-34	[224..346]	[132..237]
DRE2_ARATH - Anamorsin homolog OS=Arabidopsis thaliana GN=At5g18400 PE=1 SV=1	2.0E-30	[160..344]	[123..266]

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Predicted Domain #1

Region A:
Residues: [1-183]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQYKTGLLL IHPAVTTTPE LVENTKAQAA SKKVKFVDQF LINKLNDGSI TLENAKYETV  60
   61 HYLTPEAQTD IKFPKKLISV LADSLKPNGS LIGLSDIYKV DALINGFEII NEPDYCWIKM 120
  121 DSSKLNQTVS IPLKKKKTNN TKLQSGSKLP TFKKASSSTS NLPSFKKADH SRQPIVKETD 180
  181 SFK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [184-348]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPSFKMTTEP KVYRVVDDLI EDSDDDDFSS DSSKAQYFDQ VDTSDDSIEE EELIDEDGSG  60
   61 KSMITMITCG KSKTKKKKAC KDCTCGMKEQ EENEINDIRS QQDKVVKFTE DELTEIDFTI 120
  121 DGKKVGGCGS CSLGDAFRCS GCPYLGLPAF KPGQPINLDS ISDDL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits