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View Structure Prediction Details

Protein: CAF4
Organism: Saccharomyces cerevisiae
Length: 659 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CAF4.

Description E-value Query
Range
Subject
Range
CAF4 - WD40 repeat-containing protein associated with the CCR4-NOT complex, interacts in a Ccr4p-dependent ...
0.0 [1..659] [1..659]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
0.0 [95..659] [903..1481]
gi|17225208 - gi|17225208|gb|AAL37300.1|AF323584_1 beta transducin-like protein HET-E2C*40 [Podospora anserina]
0.0 [207..658] [821..1247]

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Predicted Domain #1
Region A:
Residues: [1-268]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTYKITTSES KKEYLYMGSG DTRGESSLVA KPIEIILNKL PHAILAQQQF QKYITSPIYR  60
   61 YLSKLLLFRE VAWPESTKDT QKGQVGIFSF QNNYADSATT FRILAHLDEH GYPLPNGAAE 120
  121 KNLPSLFEGF KATVSIIQQR LLLDNVDGAT NSDKEKYVQL PDINTGFVNK TYSRIDLTHL 180
  181 LEDVETNVEN LSINKTLEMD ELTRLDSMIN ELESRKLKIL ERVKHIDSKS TNLENDVTLI 240
  241 KDRINFIEEY NLEADREQSL RKQMEEER

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [269-659]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSEASSFTQN EEAISSLCDV ESKDTRLKDF YKMPHEKSHD KNRQIISETY SRNTTAFRMT  60
   61 IPHGEHGNSI TALDFDTPWG TLCSSSYQDR IVKVWDLNHG IQVGELPGHL ATVNCMQIDK 120
  121 KNYNMLITGS KDATLKLWDL NLSREIYLDH SPLKEKTEEI VTPCIHNFEL HKDEITALSF 180
  181 DSEALVSGSR DKKIFHWDLT TGKCIQQLDL IFTPTHSDIK MPARSLNNGA CLLGTEAPMI 240
  241 GALQCYNSAL ATGTKDGIVR LWDLRVGKPV RLLEGHTDGI TSLKFDSEKL VTGSMDNSVR 300
  301 IWDLRTSSIL DVIAYDLPVS SLDFDGKLIT VGANEGGVNV FNMERDEHWM TPEPPHSLDG 360
  361 DELSRRIAIV KYKDGFLING HNDGDINVWT L

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 164.37734
Match: 1gg2B_
Description: beta1-subunit of the signal-transducing G protein heterotrimer
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [240-659]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IKDRINFIEE YNLEADREQS LRKQMEEERS SEASSFTQNE EAISSLCDVE SKDTRLKDFY  60
   61 KMPHEKSHDK NRQIISETYS RNTTAFRMTI PHGEHGNSIT ALDFDTPWGT LCSSSYQDRI 120
  121 VKVWDLNHGI QVGELPGHLA TVNCMQIDKK NYNMLITGSK DATLKLWDLN LSREIYLDHS 180
  181 PLKEKTEEIV TPCIHNFELH KDEITALSFD SEALVSGSRD KKIFHWDLTT GKCIQQLDLI 240
  241 FTPTHSDIKM PARSLNNGAC LLGTEAPMIG ALQCYNSALA TGTKDGIVRL WDLRVGKPVR 300
  301 LLEGHTDGIT SLKFDSEKLV TGSMDNSVRI WDLRTSSILD VIAYDLPVSS LDFDGKLITV 360
  361 GANEGGVNVF NMERDEHWMT PEPPHSLDGD ELSRRIAIVK YKDGFLINGH NDGDINVWTL 420
  421 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 78.0
Match: 2ovpB
Description: No description for 2ovpB was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle