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View Structure Prediction Details

Protein: SAP190
Organism: Saccharomyces cerevisiae
Length: 1098 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SAP190.

Description E-value Query
Range
Subject
Range
SAP190 - Protein that forms a complex with the Sit4p protein phosphatase and is required for its function; me...
0.0 [1..1098] [1..1098]
gi|6179410 - gi|6179410|emb|CAB59918.1| hypothetical phosphatase associated protein [Candida albicans]
0.0 [1..768] [1..708]
gi|119595117, gi... - gi|13489083|ref|NP_060782.2| SAPS domain family, member 3 [Homo sapiens], gi|119595118|gb|EAW74712.1...
0.0 [319..993] [44..709]

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Predicted Domain #1
Region A:
Residues: [1-88]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGSFWKFGQ DYSIESPVSK ILNSAFIKIN KDQDDDVPTG TCEENIADDE DNSSHDYAAS  60
   61 EDNVVNENEE KEEENTLPTT ESEYENYR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.858 0.922 G1/S transition of mitotic cell cycle a.74.1 Cyclin-like

Predicted Domain #2
Region A:
Residues: [89-577]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNLDVLDDLL DDDELYTELM CSNFKLLIFL KYPDVLSKLI EYVTNEKILD EETDSAKKPE  60
   61 IIEGVNDHPI LIERDRKDKK EDAEEGGDSE ETTNDSDHDS GDERSVDSEE TSITLPPESE 120
  121 EQVETRRARI AAEILSADVW PISAAIMQNK DLLGRLWSIL DHPAPLPIPA STYFMKINER 180
  181 LLDMDITGML EFILSRDSLV ARFLTHVDNP SLMDFLLKVI STDKPDSPTG VIKILKSQEL 240
  241 IPKLLDHLNP EYGISTQSAA GDFIKAFVTL STNSSNELAS GIGPNELTRQ LVSEEMIEKL 300
  301 IKIMLKGGTS LSNGVGIIIE LIRKNNSDYD FIQLVYTTLE SHPPTDRDPI HLIHLVKLFA 360
  361 KHMPDFADML DKTKLPLMEM PFGNIEPLGF ERFKICELIA ELLHCSNMTL LNEPNGEMIA 420
  421 QERDIERAKE LETSTEKENI TAIVDNKSSY YDKDCVEKDI TENLGALQIN NQGSEEDELN 480
  481 DTGVSSVKL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [578-770]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVKSDAKVVE GLENDASGVE LYDETLSDTE SVRECLREKP LVGDRLKIAL EDTKILISIL  60
   61 DMFTEFPWNN FLHNVIFDIA QQIFNGPLKT GYNRFLLKDY LVDAYLTKKI VDADKACQDY 120
  121 EKKTGLRYGY MGHLTLVAEE ISKFKEYIDE MKLTFCNTAV SDRLEEPFWK EYSETILADT 180
  181 REKYNTVLGD FGN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [771-1003]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DQESDDDVIR NSDSEDIIGD TEGNENYGNG ENDELLSNGH DSGNMDLYYN FNNNENEENE  60
   61 EDYAEYSDVD NKNYYNNVET NDDDYDSDDG KSKSAESEFT DKISEHRDGN SLYNEDNDEN 120
  121 GSDKWTSGTS LFPPDHFPSR SQPSDPKLQD QNIFHHQFDF EGVGDDDDYM DPNDDGQSYA 180
  181 RPGNPLYTTP KTPPRPKTIL FNSLSALDNN GEDEEVALGT SVDDRMDNEI SSD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [1004-1098]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEDSEMKMKR MIWAMRRATH YIGQEVKKLS ELKHSHCHIF TLYSSIFYCS TFFAYRSFII  60
   61 HQIYTFLIEA CNLILTEYNL IKNNEYSLLN ILKFI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.868 0.006 protein serine/threonine phosphatase activity a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain

Predicted Domain #6
Region A:
Residues: [776-1098]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDVIRNSDSE DIIGDTEGNE NYGNGENDEL LSNGHDSGNM DLYYNFNNNE NEENEEDYAE  60
   61 YSDVDNKNYY NNVETNDDDY DSDDGKSKSA ESEFTDKISE HRDGNSLYNE DNDENGSDKW 120
  121 TSGTSLFPPD HFPSRSQPSD PKLQDQNIFH HQFDFEGVGD DDDYMDPNDD GQSYARPGNP 180
  181 LYTTPKTPPR PKTILFNSLS ALDNNGEDEE VALGTSVDDR MDNEISSDEE DSEMKMKRMI 240
  241 WAMRRATHYI GQEVKKLSEL KHSHCHIFTL YSSIFYCSTF FAYRSFIIHQ IYTFLIEACN 300
  301 LILTEYNLIK NNEYSLLNIL KFI

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.01
Match: 1ux6A
Description: Structure of a thrombospondin C-terminal fragment reveals a novel calcium core in the type 3 repeats
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle