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View Structure Prediction Details

Protein: OSH6
Organism: Saccharomyces cerevisiae
Length: 448 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for OSH6.

Description E-value Query
Range
Subject
Range
OSH6_YEAST - Oxysterol-binding protein homolog 6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=OSH6...
OSH6 - Member of an oxysterol-binding protein family with overlapping, redundant functions in sterol metabo...
0.0 [1..448] [1..448]
OSBPL8 - oxysterol binding protein-like 8
ENSPTRT00000009639 - null
gi|168278895 - gi|168278895|dbj|BAG11327.1| oxysterol-binding protein-related protein 8 [synthetic construct]
0.0 [15..445] [374..800]
OBPAL_CANAL - Oxysterol-binding protein-like protein OBPalpha OS=Candida albicans GN=OBPALPHA PE=3 SV=1
OBPAL_CANAL - Oxysterol-binding protein-like protein OBPalpha OS=Candida albicans (strain SC5314 / ATCC MYA-2876) ...
0.0 [6..433] [3..428]

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Predicted Domain #1
Region A:
Residues: [1-448]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSKKLTVGS DSHRLSKSSF SSNKSSHSAT KDQPIDTDDI DEDDESGHNI ILNIISQLRP  60
   61 GCDLTRITLP TFILEKKSML ERVTNQLQFP EFLLQAHSEK DPLKRFLYVM KWYLAGWHIA 120
  121 PKAVKKPLNP VLGEYFTAYW DLPNKQQAYY ISEQTSHHPP ECAYFYMIPE SSIRVDGVVI 180
  181 PKSRFLGNSS AAMMDGSTVL QFLDIKDGNG KPEKYVLTQP NVYVRGILFG KMRIELGDHM 240
  241 IIKSPNFQAD IEFKTKGYVF GTYDAIEGTV KDYDGNAYYE ISGKWNDVMY LKDLKQPRSS 300
  301 PKVFLDTHKE SPLRPKVRPL SEQGEYESRK LWKKVTDALA VRNHPVATEE KFQIEDHQRQ 360
  361 LAKKRIEDGV EFHPKLFRRS KPGEDLDYCI YKNIPVDEDP EKQIRSILQI APILPGQQFT 420
  421 DKFFIPAFEK IKSQKKMIEN EKQNPAKQ

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 240.853872
Match: PF01237
Description: Oxysterol-binding protein

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
oxysterol binding 5.03243665769579 bayes_pls_golite062009
sterol binding 4.18891468109664 bayes_pls_golite062009
3.02967613614595 bayes_pls_golite062009
steroid binding 2.54679035876403 bayes_pls_golite062009
phosphoinositide binding 2.2725849852584 bayes_pls_golite062009
phospholipid binding 2.08170907241909 bayes_pls_golite062009
binding 1.90982981425351 bayes_pls_golite062009
cholesterol binding 1.74311885098566 bayes_pls_golite062009
phosphatidylinositol-4,5-bisphosphate binding 1.72950454023501 bayes_pls_golite062009
lipid binding 1.52883493550389 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle