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View Structure Prediction Details

Protein: DGR2
Organism: Saccharomyces cerevisiae
Length: 852 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DGR2.

Description E-value Query
Range
Subject
Range
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
0.0 [174..826] [865..1486]
Y163_SYNY3 - Uncharacterized WD repeat-containing protein sll0163 OS=Synechocystis sp. (strain ATCC 27184 / PCC 6...
Y163_SYNY3 - Uncharacterized WD repeat-containing protein sll0163 OS=Synechocystis sp. (strain PCC 6803 / Kazusa)...
gi|7446132 - pir||S76086 beta transducin-like protein, 190K - Synechocystis sp. (strain PCC 6803)
0.0 [59..750] [1026..1677]
gi|17225210 - gi|17225210|gb|AAL37301.1|AF323585_1 beta transducin-like protein HET-D2Y [Podospora anserina]
0.0 [81..662] [823..1364]
DGR2_YEAST - 2-deoxy-glucose resistant protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DGR2...
DGR2 - Protein of unknown function; null mutant is resistant to 2-deoxy-D-glucose and displays abnormally e...
0.0 [1..852] [1..852]

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Predicted Domain #1
Region A:
Residues: [1-107]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFKSKTSTLS YDETPNSNEG DRNATPVNPK EKSQTKHLNI PGDRSRHSSI ADSKRSSSRY  60
   61 DGGYSADIIP AQLRFIDNID YGTRLRKTLH RNSVVSNGYN KLSENDR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [108-274]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WYFDLFDRKY FENYLEEPTY IKIFKKKEGL EQFDRMFLAQ ELKIPDVYKS TTYQGEPAVA  60
   61 NSELFKNSIC CCTFSHDGKY MVIGCKDGSL HLWKVINSPV KRSEMGRSEK SVSASRANSL 120
  121 KIQRHLASIS SHNGSISSND LKPSDQFEGP SKQLHLYAPV FYSDVFR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 126.28043
Match: 1erjA_
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [275-611]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VFMEHALDIL DANWSKNGFL ITASMDKTAK LWHPERKYSL KTFVHPDFVT SAIFFPNDDR  60
   61 FIITGCLDHR CRLWSILDNE VSYAFDCKDL ITSLTLSPPG GEYTIIGTFN GYIYVLLTHG 120
  121 LKFVSSFHVS DKSTQGTTKN SFHPSSEYGK VQHGPRITGL QCFFSKVDKN LRLIVTTNDS 180
  181 KIQIFDLNEK KPLELFKGFQ SGSSRHRGQF LMMKNEPVVF TGSDDHWFYT WKMQSFNLSA 240
  241 EMNCTAPHRK KRLSGSMSLK GLLRIVSNKS TNDECLTETS NQSSSHTFTN SSKNVLQTQT 300
  301 VGSQAIKNNH YISFHAHNSP VTCASIAPDV AIKNLSL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.221849
Match: 1scgB_
Description: No description for 1scgB_ was found.

Predicted Domain #4
Region A:
Residues: [612-852]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNDLIFELTS QYFKEMGQNY SESKETCDNK PNHPVTETGG FSSNLSNVVN NVGTILITTD  60
   61 SQGLIRVFRT DILPEIRKKI IEKFHEYNLF HLEAAGKINN HNNDSILENR MDERSSTEDN 120
  121 EFSTTPPSNT HNSRPSHDFC ELHPNNSPVI SGMPSRASAI FKNSIFNKSN GSFISLKSRS 180
  181 ESTSSTVFGP HDIPRVSTTY PKLKCDVCNG SNFECASKNP IAGGDSGFTC ADCGTILNNF 240
  241 R

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.69897
Match: 1c5kA_
Description: TolB, C-terminal domain; TolB, N-terminal domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle