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View Structure Prediction Details

Protein: YKL105C
Organism: Saccharomyces cerevisiae
Length: 1132 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YKL105C.

Description E-value Query
Range
Subject
Range
gi|151941698 - gi|151941698|gb|EDN60060.1| conserved protein [Saccharomyces cerevisiae YJM789]
SEG2_YEAST - Eisosome protein SEG2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SEG2 PE=1 SV=1
YKL105C - Putative protein of unknown function
8.0E-93 [1..1132] [1..1132]
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1
2.0E-89 [239..992] [837..1606]
MYH2_BOVIN - Myosin-2 OS=Bos taurus GN=MYH2 PE=2 SV=1
1.0E-87 [244..992] [845..1609]
MYH4_RABIT - Myosin-4 OS=Oryctolagus cuniculus GN=MYH4 PE=1 SV=1
3.0E-86 [239..992] [838..1607]
gi|9800488, gi|1... - gi|9800488|gb|AAF99315.1|AF272034_1 fast myosin heavy chain isoform 3 [Gallus gallus], gi|165973976|...
2.0E-85 [239..1032] [840..1650]
MYSS_CYPCA - Myosin heavy chain, fast skeletal muscle OS=Cyprinus carpio PE=2 SV=2
2.0E-85 [239..989] [836..1602]
gi|14250231, gi|... - ref|NP_659210.1| myosin, heavy polypeptide 2, skeletal muscle, adult [Mus musculus], gi|14250231|gb...
2.0E-85 [239..963] [842..1582]
MYH1 - myosin, heavy chain 1, skeletal muscle, adult
3.0E-85 [239..992] [839..1608]

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Predicted Domain #1
Region A:
Residues: [1-142]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIQESSPDAL AAAAAIGNAL SYNGRTVDKS KIPQYNQSFT SRTTSIAGIN RYTMLSNSRT  60
   61 NSRMLLMNGN VRQYSKRTSS LPNQGHKNTS NNSAGRRQHR AHEDAETTFR EFGGKQSSKV 120
  121 LNISSSTGQN SKSRTTSLGN SG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [143-501]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STIRTIKKYI PGPRGLMAVE VPVEVEPPRY SLSNRSNQRG GRAYSLPTRN NKTSLMHRNK  60
   61 TTKKAGSQEK KSESGGKSKN DYHGKVLSKM HTTSLKQRHN NVPLIPTTMN EETEQELQED 120
  121 LHDPLEFKPM IISDDENSFI EPSVLDRSIP KKDKSGLSGR EKKEEIETLL KEVHSLEEKI 180
  181 SNIEIAKLNE EEREQSLILE LRKVKLDEER RMELLKRELN IVKENADLEA QELKLIESKR 240
  241 KQHFHKGQEV ASEVKSITIR QPTLSEPKPA YVPPEDVEKE PSTLSNQTQN IENAENIDSV 300
  301 DAEGNLVDPI LLGSLNNSNF HMNSDNEVRC IADSNSLTGS ELSDYNYIEG SATDLRATA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.30103
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [502-573]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTSVESEIGG NQVGLKIPQD DDSEKQEERT KGKKSGLVDT NCFLVQKEDQ EEALSDNEPE  60
   61 SSEKFPSTSG IE

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.25
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #4
Region A:
Residues: [574-656]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVKLEDETGS VMDKNNGPNN DKDDDDDKDN DNDDDDDKDD DVNDDDKDEN VDDDENVDDD  60
   61 DDDDDDDDDE YHDSYDVIMR DPV

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.25
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #5
Region A:
Residues: [657-726]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QIEQDISDVP SLKHPSEYST ETEDNKKKEQ NSENAEVSQS GTNMAKYLRG ANPYLTNTSS  60
   61 DTFSLDSENV 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.25
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #6
Region A:
Residues: [727-811]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSKSSTDTTR VAPDLLKSSL QPQLRSDLKQ SAVPSSTSSS IYSIETSPNI DSSTGKTASN  60
   61 TKTNSHGPPT SISKQKYDQS SSHQI

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.25
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #7
Region A:
Residues: [812-899]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVMSPKRLDD KRKITNRSCL RTLRGSSNEA TLSHNIVYPA SDSSSSPPYH SKKPSNPPSS  60
   61 GNLASHEASK CFPKAPQAST TSRRLPDH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [900-1132]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPLYIDKNNS ALYPKEPPAR KSSFEKERPA KDNLGFRSMS LREPLITKNA TATAAENLDV  60
   61 EEKKEKGGHV SRKSWTFGLP SPLKRRTSHS THTTNETEIV NPMTNFKNKT NENDMPILAN 120
  121 KKSCNNDDSS PYTASSMNTN DVSEAGTEGH RFSLFGNKSQ LSNRNISGGT ATLESSNPDL 180
  181 PTALPLSVPV TIIDKNGEIH KLHNDDAAIK DKSHDRHGHS KFGRKLKKIF GRK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle