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View Structure Prediction Details

Protein: YPF1
Organism: Saccharomyces cerevisiae
Length: 587 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YPF1.

Description E-value Query
Range
Subject
Range
YKK0_YEAST - Probable intramembrane protease YKL100C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=...
gi|151941702 - gi|151941702|gb|EDN60064.1| conserved protein [Saccharomyces cerevisiae YJM789]
YPF1 - Putative protein of unknown function with similarity to a human minor histocompatibility antigen and...
0.0 [1..564] [1..564]
gi|73909060, gi|... - gi|73909060|gb|AAH22041.2| Intramembrane protease 5 [Homo sapiens], gi|19263993|gb|AAH25401.1| Intra...
3.0E-77 [307..573] [324..602]
imp-2 - Yeast YKK0 like status:Confirmed UniProt:P49049 protein_id:CAA92975.1
2.0E-76 [288..527] [229..468]
SIPL2_ARATH - Signal peptide peptidase-like 2 OS=Arabidopsis thaliana GN=SPPL2 PE=2 SV=1
2.0E-75 [305..523] [322..540]
gi|16118854 - gi|16118854|gb|AAL14628.1|AF417575_1 growth-on protein GRO11 [Euphorbia esula]
2.0E-72 [306..522] [322..537]
HM13_MOUSE - Minor histocompatibility antigen H13 OS=Mus musculus GN=Hm13 PE=1 SV=1
2.0E-72 [294..525] [148..377]
Spp-PA - The gene Signal peptide protease is referred to in FlyBase by the symbol Dmel\Spp (CG11840, FBgn0031...
gi|220947006 - gi|220947006|gb|ACL86046.1| Spp-PA [synthetic construct]
1.0E-71 [294..507] [157..356]

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Predicted Domain #1
Region A:
Residues: [1-259]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKYLNSFVD HLSEWSSRAF RNNSSSANQS ASNKELEQVF EQINAIVENH NNKLTTAFDK  60
   61 ISYRVAHKIT HLVESHSLVF NYATLVLIAS ALVVIGSFTS ISSIPFTALP PTREHSLFDP 120
  121 TDFDVDHDCH VIYRENDEDK KKKKKSKRFF DMMDEKHAII LPLTSGCTLL ALYFVIKKLH 180
  181 LNWLKYVVKI LNFNITLLNI PAGTFVYSYF LNSLFRNLSH LASWNPLVVL PRYRVTIADD 240
  241 NEDLNKIGGF VTNLNYKDG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [260-587]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LTNSVVHKKT LDEIEKDHWM KHFYRRELVE PKDIKSKRQI SNMYLNSALI VSFVLSIVST  60
   61 VYFYLSPNDW LISNAVSMNM AIWSIAQLKL KNLKSGALIL IALFFYDICF VFGTDVMVTV 120
  121 ATNLDIPVKL SLPVKFNTAQ NNFNFSILGL GDIALPGMFI AMCYKYDIWK WHLDHDDTEF 180
  181 HFLNWSYVGK YFITAMVSYV ASLVSAMVSL SIFNTAQPAL LYIVPSLLIS TILVACWNKD 240
  241 FKQFWNFQYD TIEVDKSLKK AIEKKENSIT YSTFILSEYY NDADKYALLG DDVNENFDDD 300
  301 EEFVQEEDLS DSSEEELSEE DLLDDESS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [289-474]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPKDIKSKRQ ISNMYLNSAL IVSFVLSIVS TVYFYLSPND WLISNAVSMN MAIWSIAQLK  60
   61 LKNLKSGALI LIALFFYDIC FVFGTDVMVT VATNLDIPVK LSLPVKFNTA QNNFNFSILG 120
  121 LGDIALPGMF IAMCYKYDIW KWHLDHDDTE FHFLNWSYVG KYFITAMVSY VASLVSAMVS 180
  181 LSIFNT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [475-587]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AQPALLYIVP SLLISTILVA CWNKDFKQFW NFQYDTIEVD KSLKKAIEKK ENSITYSTFI  60
   61 LSEYYNDADK YALLGDDVNE NFDDDEEFVQ EEDLSDSSEE ELSEEDLLDD ESS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.974
Match: 4hb1A
Description: A DESIGNED FOUR HELIX BUNDLE PROTEIN.
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle