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View Structure Prediction Details

Protein: TEF4
Organism: Saccharomyces cerevisiae
Length: 412 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TEF4.

Description E-value Query
Range
Subject
Range
gi|15530265 - gi|15530265|gb|AAH13918.1| Eukaryotic translation elongation factor 1 gamma [Homo sapiens]
0.0 [1..412] [1..437]
EF1G_MOUSE - Elongation factor 1-gamma OS=Mus musculus GN=Eef1g PE=1 SV=3
0.0 [1..412] [1..437]
EF1G_RABIT - Elongation factor 1-gamma OS=Oryctolagus cuniculus GN=EEF1G PE=2 SV=3
0.0 [1..412] [1..437]
EF1G_PIG - Elongation factor 1-gamma (Fragment) OS=Sus scrofa GN=EEF1G PE=2 SV=2
0.0 [6..412] [1..432]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [1..412] [1..436]
EF1GA_XENLA - Elongation factor 1-gamma-A OS=Xenopus laevis GN=eef1g-a PE=1 SV=1
0.0 [1..412] [1..436]
EF1G_CARAU - Elongation factor 1-gamma OS=Carassius auratus GN=eef1g PE=2 SV=1
0.0 [1..412] [1..442]

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Predicted Domain #1
Region A:
Residues: [1-80]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQGTLYINR SPRNYASEAL ISYFKLDVKI VDLEQSSEFA SLFPLKQAPA FLGPKGLKLT  60
   61 EALAIQFYLA NQVADEKERA 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 66.533179
Match: 1bx9A_
Description: Class phi GST
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.30799114442278 bayes_pls_golite062009
nucleic acid binding 2.06381591939564 bayes_pls_golite062009
DNA binding 1.92118545500784 bayes_pls_golite062009
binding 1.25802922431343 bayes_pls_golite062009
transcription activator activity 1.23146660729357 bayes_pls_golite062009
protein binding 1.18479617596618 bayes_pls_golite062009
catalytic activity 0.672192331361968 bayes_pls_golite062009
RNA binding 0.382017633056715 bayes_pls_golite062009
0.359224524631956 bayes_pls_golite062009
receptor binding 0.0497559408754589 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [81-247]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLLGSDVIEK SQILRWASLA NSDVMSNIAR PFLSFKGLIP YNKKDVDACF VKIDNLAAVF  60
   61 DARLRDYTFV ATENISLGDL HAAGSWAFGL ATILGPEWRA KHPHLMRWFN TVAASPIVKT 120
  121 PFAEVKLAEK ALTYTPPKKQ KAEKPKAEKS KAEKKKDEAK PADDAAP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 66.533179
Match: 1bx9A_
Description: Class phi GST
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
translation elongation factor activity 11.9602302019768 bayes_pls_golite062009
translation factor activity, nucleic acid binding 7.4644014407268 bayes_pls_golite062009
translation regulator activity 7.42485540728491 bayes_pls_golite062009
nucleic acid binding 3.9329721501879 bayes_pls_golite062009
binding 3.0325775548747 bayes_pls_golite062009
protein binding 1.65598815428763 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [248-412]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKKPKHPLEA LGKSTFVLDD WKRKYSNDDT RPVALPWFWE HYNPEEYSIW KVGYKYNDEL  60
   61 TLTFMSNNLV GGFFNRLSAS TKYMFGCLVV YGENNNNGIV GAVMVRGQDF APAFDVAPDW 120
  121 ESYEYTKLDP TKEEDKEFVN NMWAWDKPVV VNGEDKEIVD GKVLK

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 81.920819
Match: PF00647
Description: Elongation factor 1 gamma, conserved domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle