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View Structure Prediction Details

Protein: LHS1
Organism: Saccharomyces cerevisiae
Length: 881 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LHS1.

Description E-value Query
Range
Subject
Range
HSP70_TRIRU - Heat shock 70 kDa protein OS=Trichophyton rubrum GN=HSP70 PE=2 SV=1
0.0 [19..680] [1..610]
gi|6969976 - gi|6969976|gb|AAF34134.1| high molecular weight heat shock protein [Malus x domestica]
0.0 [14..716] [1..650]
gi|2894792, gi|1... - gi|2894792|gb|AAC02807.1| heat shock protein 70 [Cryptosporidium parvum], gi|1616783|gb|AAB16853.1| ...
0.0 [17..682] [3..617]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [17..716] [3..641]
HSP70_LEIDO - Heat shock 70 kDa protein OS=Leishmania donovani GN=HSP70 PE=3 SV=1
0.0 [22..682] [6..615]
HSP7C_ICTPU - Heat shock cognate 71 kDa protein OS=Ictalurus punctatus GN=hsc70 PE=2 SV=1
0.0 [18..682] [2..613]
HSP70_MAIZE, HS7... - Heat shock 70 kDa protein OS=Zea mays GN=HSP70 PE=3 SV=1, (P11143) Heat shock 70 kDa protein
0.0 [17..716] [3..645]
gi|3114993 - gi|3114993|emb|CAA75383.1| heat shock protein 70 [Sycon raphanus]
0.0 [22..716] [3..656]
HS71B_BOVIN - Heat shock 70 kDa protein 1B OS=Bos taurus GN=HSPA1B PE=2 SV=1
0.0 [18..680] [2..611]
gi|7861932, gi|1... - gi|7861932|gb|AAF70445.1| Hsp70 [Danio rerio], gi|18858871|ref|NP_571472.1| heat shock cognate 70-kd...
0.0 [17..704] [3..637]

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Predicted Domain #1
Region A:
Residues: [1-209]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRNVLRLLFL TAFVAIGSLA AVLGVDYGQQ NIKAIVVSPQ APLELVLTPE AKRKEISGLS  60
   61 IKRLPGYGKD DPNGIERIYG SAVGSLATRF PQNTLLHLKP LLGKSLEDET TVTLYSKQHP 120
  121 GLEMVSTNRS TIAFLVDNVE YPLEELVAMN VQEIANRANS LLKDRDARTE DFVNKMSFTI 180
  181 PDFFDQHQRK ALLDASSITT GIEETYLVS

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [420-438]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESAVNGVVMR GIKLSNSFK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1276.9897
Match: 1ba0__
Description: Heat shock protein 70kDa, ATPase fragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [210-276]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGMSVAVNFV LKQRQFPPGE QQHYIVYDMG SGSIKASMFS ILQPEDTTQP VTIEFEGYGY  60
   61 NPHLGGA

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [356-419]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADSLLDIVKP INDAVTKQFG GYGTNLPEIN GVILAGGSSR IPIVQDQLIK LVSEEKVLRN  60
   61 VNAD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1276.9897
Match: 1ba0__
Description: Heat shock protein 70kDa, ATPase fragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [277-355]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KFTMDIGSLI ENKFLETHPA IRTDELHANP KALAKINQAA EKAKLILSAN SEASINIESL  60
   61 INDIDFRTSI TRQEFEEFI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1276.9897
Match: 1ba0__
Description: Heat shock protein 70kDa, ATPase fragment
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [439-602]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKPLNVVDRS VNTYSFKLSN ESELYDVFTR GSAYPNKTSI LTNTTDSIPN NFTIDLFENG  60
   61 KLFETITVNS GAIKNSYSSD KCSSGVAYNI TFDLSSDRLF SIQEVNCICQ SENDIGNSKQ 120
  121 IKNKGSRLAF TSEDVEIKRL SPSERSRLHE HIKLLDKQDK ERFQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 85.0
Match: 1dkxA_
Description: DnaK
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [603-709]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FQENLNVLES NLYDARNLLM DDEVMQNGPK SQVEELSEMV KVYLDWLEDA SFDTDPEDIV  60
   61 SRIREIGILK KKIELYMDSA KEPLNSQQFK GMLEEGHKLL QAIETHK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 85.0
Match: 1dkxA_
Description: DnaK
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [710-881]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTVEEFLSQF ETEFADTIDN VREEFKKIKQ PAYVSKALST WEETLTSFKN SISEIEKFLA  60
   61 KNLFGEDLRE HLFEIKLQFD MYRTKLEEKL RLIKSGDESR LNEIKKLHLR NFRLQKRKEE 120
  121 KLKRKLEQEK SRNNNETEST VINSADDKTT IVNDKTTESN PSSEEDILHD EL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle