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View Structure Prediction Details

Protein: MPE1
Organism: Saccharomyces cerevisiae
Length: 441 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MPE1.

Description E-value Query
Range
Subject
Range
gi|151941487 - gi|151941487|gb|EDN59850.1| mutant pcf11 extragenic suppressor [Saccharomyces cerevisiae YJM789]
MPE1 - Essential conserved subunit of CPF (cleavage and polyadenylation factor), plays a role in 3' end for...
gi|207343504 - gi|207343504|gb|EDZ70948.1| YKL059Cp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190409770 - gi|190409770|gb|EDV13035.1| protein MPE1 [Saccharomyces cerevisiae RM11-1a]
MPE1_YEAST - Protein MPE1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MPE1 PE=1 SV=1
0.0 [1..441] [1..441]
gi|15238091 - gi|15238091|ref|NP_199554.1| unknown protein [Arabidopsis thaliana]
9.0E-86 [5..432] [3..438]
YORF_SCHPO - Uncharacterized RING finger protein P8B7.15c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) ...
SPBP8B7.15c - ubiquitin-protein ligase E3 RBBP6 family
2.0E-76 [1..419] [1..416]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
3.0E-71 [3..435] [2..453]
gi|18845848 - gi|18845848|gb|AAL18101.1| recombination activating protein 1 [Chloropsis cochinchinensis]
3.0E-56 [128..383] [100..353]
gi|18845874 - gi|18845874|gb|AAL18114.1| recombination activating protein 1 [Hirundo pyrrhonota]
gi|18845874 - gi|18845874|gb|AAL18114.1| recombination activating protein 1 [Hirundo pyrrhonota]
3.0E-56 [128..383] [100..353]

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Predicted Domain #1
Region A:
Residues: [1-69]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSTIFYRFK SQRNTSRILF DGTGLTVFDL KREIIQENKL GDGTDFQLKI YNPDTEEEYD  60
   61 DDAFVIPRS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [70-268]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSVIVKRSPA IKSFSVHSRL KGNVGAAALG NATRYVTGRP RVLQKRQHTA TTTANVSGTT  60
   61 EEERIASMFA TQENQWEQTQ EEMSAATPVF FKSQTNKNSA QENEGPPPPG YMCYRCGGRD 120
  121 HWIKNCPTNS DPNFEGKRIR RTTGIPKKFL KSIEIDPETM TPEEMAQRKI MITDEGKFVV 180
  181 QVEDKQSWED YQRKRENRQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [269-441]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IDGDETIWRK GHFKDLPDDL KCPLTGGLLR QPVKTSKCCN IDFSKEALEN ALVESDFVCP  60
   61 NCETRDILLD SLVPDQDKEK EVETFLKKQE ELHGSSKDGN QPETKKMKLM DPTGTAGLNN 120
  121 NTSLPTSVNN GGTPVPPVPL PFGIPPFPMF PMPFMPPTAT ITNPHQADAS PKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.221849
Match: 1rmd__
Description: V(D)J recombination activating protein 1 (RAG1), dimerization domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [227-441]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ETMTPEEMAQ RKIMITDEGK FVVQVEDKQS WEDYQRKREN RQIDGDETIW RKGHFKDLPD  60
   61 DLKCPLTGGL LRQPVKTSKC CNIDFSKEAL ENALVESDFV CPNCETRDIL LDSLVPDQDK 120
  121 EKEVETFLKK QEELHGSSKD GNQPETKKMK LMDPTGTAGL NNNTSLPTSV NNGGTPVPPV 180
  181 PLPFGIPPFP MFPMPFMPPT ATITNPHQAD ASPKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.0
Match: 2cklB
Description: No description for 2cklB was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle