YRC Public Data Repository - Protein Structure Prediction

Protein:	UGP1
Organism:	Saccharomyces cerevisiae
Length:	499 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UGP1.

Description	E-value	Query Range	Subject Range
gi\|190409789 - gi\|190409789\|gb\|EDV13054.1\| UTP-glucose-1-phosphate uridylyltransferase [Saccharomyces cerevisiae RM... gi\|151941509 - gi\|151941509\|gb\|EDN59872.1\| uridinephosphoglucose pyrophosphorylase [Saccharomyces cerevisiae YJM789... UGPA1_YEAST - UTP--glucose-1-phosphate uridylyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c... gi\|207343473 - gi\|207343473\|gb\|EDZ70924.1\| YKL035Wp-like protein [Saccharomyces cerevisiae AWRI1631] UGP1 - UDP-glucose pyrophosphorylase (UGPase), catalyses the reversible formation of UDP-Glc from glucose 1...	0.0	[1..499]	[1..499]
gi\|7415873 - gi\|7415873\|dbj\|BAA93572.1\| Ugp1 [Candida glabrata]	0.0	[1..499]	[1..502]
SPCC1322.04 - UTP-glucose-1-phosphate uridylyltransferase UGPA1_SCHPO - Probable UTP--glucose-1-phosphate uridylyltransferase OS=Schizosaccharomyces pombe (strain 972 / ATC...	0.0	[4..499]	[10..506]
gi\|7417426 - gi\|7417426\|gb\|AAF62555.1\|AF249880_1 UDP-glucose pyrophosphorylase [Oryza sativa subsp. indica]	0.0	[32..492]	[4..463]
UGPA_MUSAC - UTP--glucose-1-phosphate uridylyltransferase OS=Musa acuminata GN=UGPA PE=2 SV=1	0.0	[33..492]	[5..463]
gi\|115480571, gi... - gi\|222642056\|gb\|EEE70188.1\| hypothetical protein OsJ_30269 [Oryza sativa Japonica Group], gi\|2157673...	0.0	[18..492]	[3..465]
UGPA1_ARATH - UTP--glucose-1-phosphate uridylyltransferase 1 OS=Arabidopsis thaliana GN=UGP1 PE=2 SV=1	0.0	[30..492]	[5..466]
UGPA_HORVU - UTP--glucose-1-phosphate uridylyltransferase OS=Hordeum vulgare PE=2 SV=1 gi\|1212996 - gi\|1212996\|emb\|CAA62689.1\| UDP-glucose pyrophosphorylase [Hordeum vulgare subsp. vulgare]	0.0	[18..492]	[6..469]
CE18871 - UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (EC 2.7.7.9) (UDP-GLUCOSE PYROPHOSPHORYLASE) (UDPGP) st...	0.0	[2..499]	[12..511]
UGPA_ASTME, UDPG... - UTP--glucose-1-phosphate uridylyltransferase OS=Astragalus membranaceus GN=UGP PE=2 SV=1, (Q9LKG7) U... UGPA_ASTPN - UTP--glucose-1-phosphate uridylyltransferase OS=Astragalus penduliflorus GN=UGP PE=2 SV=1 gi\|9280626\|gb\|AA... - UDP-glucose pyrophosphorylase [Astragalus membranaceus]	0.0	[30..492]	[6..467]

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Predicted Domain #1

Region A:
Residues: [1-96]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTKKHTKTH STYAFESNTN SVAASQMRNA LNKLADSSKL DDAARAKFEN ELDSFFTLFR  60
   61 RYLVEKSSRT TLEWDKIKSP NPDEVVKYEI ISQQPE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.851	0.088	protein amino acid glycosylation	a.40.1	Calponin-homology domain, CH-domain

Predicted Domain #2

Region A:
Residues: [97-499]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVSNLSKLAV LKLNGGLGTS MGCVGPKSVI EVREGNTFLD LSVRQIEYLN RQYDSDVPLL  60
   61 LMNSFNTDKD TEHLIKKYSA NRIRIRSFNQ SRFPRVYKDS LLPVPTEYDS PLDAWYPPGH 120
  121 GDLFESLHVS GELDALIAQG REILFVSNGD NLGATVDLKI LNHMIETGAE YIMELTDKTR 180
  181 ADVKGGTLIS YDGQVRLLEV AQVPKEHIDE FKNIRKFTNF NTNNLWINLK AVKRLIESSN 240
  241 LEMEIIPNQK TITRDGHEIN VLQLETACGA AIRHFDGAHG VVVPRSRFLP VKTCSDLLLV 300
  301 KSDLFRLEHG SLKLDPSRFG PNPLIKLGSH FKKVSGFNAR IPHIPKIVEL DHLTITGNVF 360
  361 LGKDVTLRGT VIIVCSDGHK IDIPNGSILE NVVVTGNLQI LEH

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	13.71
Match:	1hv9A
Description:	N-acetylglucosamine 1-phosphate uridyltransferase GlmU, C-terminal domain; N-acetylglucosamine 1-phosphate uridyltransferase GlmU, N-terminal domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits