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View Structure Prediction Details

Protein: MAE1
Organism: Saccharomyces cerevisiae
Length: 669 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MAE1.

Description E-value Query
Range
Subject
Range
MAOC_FLAPR - NADP-dependent malic enzyme, chloroplastic OS=Flaveria pringlei GN=MODA PE=2 SV=1
0.0 [7..654] [24..645]
MAOC_FLATR - NADP-dependent malic enzyme, chloroplastic OS=Flaveria trinervia GN=MOD1 PE=2 SV=1
0.0 [7..654] [24..646]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
0.0 [7..654] [24..646]
gi|1561774 - gi|1561774|gb|AAB08874.1| malate dehydrogenase [Vitis vinifera]
0.0 [23..655] [19..639]
MAE1 - Mitochondrial malic enzyme, catalyzes the oxidative decarboxylation of malate to pyruvate, which is ...
MAOM_YEAST - NAD-dependent malic enzyme, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) G...
0.0 [1..669] [1..669]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [18..654] [17..638]
gi|4239891 - gi|4239891|dbj|BAA74735.1| NADP-malic enzyme [Aloe arborescens]
0.0 [65..654] [12..583]

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Predicted Domain #1
Region A:
Residues: [1-97]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRTRLSVSV AARSQLTRSL TASRTAPLRR WPIQQSRLYS SNTRSHKATT TRENTFQKPY  60
   61 SDEEVTKTPV GSRARKIFEA PHPHATRLTV EGAIECP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [98-352]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LESFQLLNSP LFNKGSAFTQ EEREAFNLEA LLPPQVNTLD EQLERSYKQL CYLKTPLAKN  60
   61 DFMTSLRVQN KVLYFALIRR HIKELVPIIY TPTEGDAIAA YSHRFRKPEG VFLDITEPDS 120
  121 IECRLATYGG DKDVDYIVVS DSEGILGIGD QGIGGVRIAI SKLALMTLCG GIHPGRVLPV 180
  181 CLDVGTNNKK LARDELYMGN KFSRIRGKQY DDFLEKFIKA VKKVYPSAVL HFEDFGVKNA 240
  241 RRLLEKYRYE LPSFN

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [647-669]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWEPVYRPMI KVQHDPSVHT NQL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1976.9897
Match: 1gq2A_
Description: Mitochondrial NAD(P)-dependenent malic enzyme
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [353-646]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDIQGTGAVV MASLIAALKH TNRDLKDTRV LIYGAGSAGL GIADQIVNHM VTHGVDKEEA  60
   61 RKKIFLMDRR GLILQSYEAN STPAQHVYAK SDAEWAGINT RSLHDVVENV KPTCLVGCST 120
  121 QAGAFTQDVV EEMHKHNPRP IIFPLSNPTR LHEAVPADLM KWTNNNALVA TGSPFPPVDG 180
  181 YRISENNNCY SFPGIGLGAV LSRATTITDK MISAAVDQLA ELSPLREGDS RPGLLPGLDT 240
  241 ITNTSARLAT AVILQALEEG TARIEQEQVP GGAPGETVKV PRDFDECLQW VKAQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1976.9897
Match: 1gq2A_
Description: Mitochondrial NAD(P)-dependenent malic enzyme
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle