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View Structure Prediction Details

Protein: YJR142W
Organism: Saccharomyces cerevisiae
Length: 342 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YJR142W.

Description E-value Query
Range
Subject
Range
YJR142W - Putative protein of unknown function; GST fusion protein is a Dbf2-Mob1 phosphoylation target in a p...
YJ9J_YEAST - Uncharacterized protein YJR142W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YJR142W ...
0.0 [1..342] [1..342]
TNR3_SCHPO - Thiamine pyrophosphokinase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=tnr3 PE=3 SV=1
tnr3 - thiamine diphosphokinase Tnr3
2.0E-65 [28..339] [16..305]
NUD20_ARATH - Nudix hydrolase 20, chloroplastic OS=Arabidopsis thaliana GN=NUDT20 PE=2 SV=1
6.0E-65 [17..335] [74..371]
CG12567-PF - This gene is referred to in FlyBase by the symbol Dmel\CG12567 (CG12567, FBgn0039958). It is a prote...
1.0E-57 [51..336] [25..296]
IDI2_CAMAC - Isopentenyl-diphosphate Delta-isomerase II OS=Camptotheca acuminata GN=IPI2 PE=2 SV=1
5.0E-54 [83..323] [45..295]
gi|13603406 - gi|13603406|dbj|BAB40973.1| isopentenyl diphosphate isomerase 1 [Nicotiana tabacum]
2.0E-53 [90..323] [40..276]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-50 [64..317] [5..271]
gi|3421421, gi|2... - gi|3421421|gb|AAC32208.1| isopentenyl pyrophosphate:dimethylallyl pyrophosphate isomerase [Haematoco...
9.0E-50 [64..317] [5..283]
gi|6856556 - gi|6856556|gb|AAF29976.1|AF188063_1 isopentenyl pyrophosphate:dimethyllallyl pyrophosphate isomerase...
1.0E-49 [79..323] [10..249]
gi|9971806 - gi|9971806|gb|AAG10423.1| isopentenyl pyrophosphate:dimethyllallyl pyrophosphate isomerase [Tagetes ...
1.0E-49 [116..323] [34..248]

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Predicted Domain #1
Region A:
Residues: [1-121]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVEKSSKGL EVLVRTQEDD LEGFSFLEIM DRVDPLPLDF ENYKNFKEGI YYMCTHDGTK  60
   61 IGFVLKFAIN EMETVCSEIF EETFQLDESR HELRFKSEDF DHRNNLIDQL ARKMYLESSL 120
  121 S

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.757 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.757 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.738 d.185.1 LuxS/MPP-like metallohydrolase
View Download 0.738 d.185.1 LuxS/MPP-like metallohydrolase
View Download 0.676 a.1.1 Globin-like
View Download 0.676 a.1.1 Globin-like
View Download 0.640 c.13.2 Anti-sigma factor antagonist SpoIIaa
View Download 0.640 c.13.2 Anti-sigma factor antagonist SpoIIaa
View Download 0.628 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.628 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.580 a.4.5 "Winged helix" DNA-binding domain
View Download 0.531 a.47.2 t-snare proteins
View Download 0.520 a.19.1 Fertilization protein
View Download 0.482 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.443 a.83.1 Guanido kinase N-terminal domain
View Download 0.431 d.212.1 TolA/TonB C-terminal domain
View Download 0.424 f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.419 a.24.4 Hemerythrin
View Download 0.414 a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.414 a.1.1 Globin-like
View Download 0.399 a.118.8 TPR-like
View Download 0.387 a.7.8 GAT domain
View Download 0.386 d.93.1 SH2 domain
View Download 0.384 a.24.3 Cytochromes
View Download 0.362 d.110.4 SNARE-like
View Download 0.357 d.55.1 Ribosomal protein L22
View Download 0.352 a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.346 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.344 a.63.1 Apolipophorin-III
View Download 0.337 a.74.1 Cyclin-like
View Download 0.334 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.326 a.118.18 Cysteine rich protein B (HcpB)
View Download 0.325 a.77.1 DEATH domain
View Download 0.324 a.73.1 Retrovirus capsid protein, N-terminal core domain
View Download 0.323 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.321 d.58.8 Viral DNA-binding domain
View Download 0.317 a.25.1 Ferritin-like
View Download 0.316 d.110.4 SNARE-like
View Download 0.307 a.7.1 Spectrin repeat
View Download 0.302 f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.299 a.4.5 "Winged helix" DNA-binding domain
View Download 0.291 d.110.4 SNARE-like
View Download 0.286 d.52.3 Prokaryotic type KH domain (KH-domain type II)
View Download 0.281 a.68.1 Wiscott-Aldrich syndrome protein, WASP, C-terminal domain
View Download 0.279 d.96.1 Tetrahydrobiopterin biosynthesis enzymes-like
View Download 0.276 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.273 d.150.1 4'-phosphopantetheinyl transferase
View Download 0.272 a.118.11 Cytochrome c oxidase subunit E
View Download 0.271 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.268 d.6.1 Prion-like
View Download 0.268 a.48.1 N-terminal domain of cbl (N-cbl)
View Download 0.255 a.24.14 FAT domain of focal adhesion kinase
View Download 0.250 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.248 d.188.1 Prokaryotic ribosomal protein L17
View Download 0.246 c.114.1 YchN-like
View Download 0.245 d.208.1 MTH1598-like
View Download 0.241 d.224.1 SufE-like
View Download 0.241 c.59.1 MurD-like peptide ligases, peptide-binding domain
View Download 0.236 a.7.1 Spectrin repeat
View Download 0.236 d.52.4 YhbC-like, N-terminal domain
View Download 0.235 a.7.5 Tubulin chaperone cofactor A
View Download 0.230 a.1.1 Globin-like
View Download 0.230 a.64.1 Saposin
View Download 0.230 a.4.5 "Winged helix" DNA-binding domain
View Download 0.229 d.95.2 Homing endonucleases
View Download 0.217 a.118.10 Phosphoinositide-binding clathrin adaptor, N-terminal domain
View Download 0.212 a.47.2 t-snare proteins
View Download 0.210 d.65.1 Hedgehog/DD-pepidase
View Download 0.207 d.122.1 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
View Download 0.204 a.29.4 RecG, N-terminal domain
View Download 0.203 a.150.1 Anti-sigma factor AsiA
View Download 0.201 a.40.2 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain
View Download 0.200 f.18.1 F1F0 ATP synthase subunit A

Predicted Domain #2
Region A:
Residues: [122-342]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVKGWRNEKY AVWVNKKPYV LVERAVAGVL GIITYGIHIN GYVLDPKSKK VQFWVPRRSK  60
   61 TKQTWPLMLD NIIAGGLGYP YGIYETVLKE SMEEANLEKS VIEDNIKATG SVSYLYFTGD 120
  121 ISVTKFNKES DFIVGEVQYV YDLKLSEDII PKPNDGEVES FNLFSLQETI NALRKKEFKP 180
  181 NCALVMVDFL IRHGYITPEN EPNYLELVTR MHRRLPFPTL N

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.0
Match: 1hztA_
Description: Isopentenyl diphosphate isomerase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle