YRC Public Data Repository - Protein Structure Prediction

Protein:	TDA4
Organism:	Saccharomyces cerevisiae
Length:	279 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TDA4.

Description	E-value	Query Range	Subject Range
TDA4_YEAST - Topoisomerase I damage affected protein 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) G... gi\|151945181 - gi\|151945181\|gb\|EDN63432.1\| conserved protein [Saccharomyces cerevisiae YJM789] TDA4 - Putative protein of unknown function gi\|190409588 - gi\|190409588\|gb\|EDV12853.1\| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]	3.0E-69	[1..279]	[1..279]
gi\|157071803, gi... - gi\|164427582\|ref\|XP_965364.2\| hypothetical protein NCU02977 [Neurospora crassa OR74A], gi\|157071803\|... gi\|16945392 - gi\|16945392\|emb\|CAB97314.2\| conserved hypothetical protein [Neurospora crassa]	5.0E-54	[32..277]	[32..309]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	2.0E-50	[32..277]	[32..335]
gi\|79319015, gi\|... - gi\|79319015\|ref\|NP_001031121.1\| unknown protein [Arabidopsis thaliana], gi\|20466069\|gb\|AAM19956.1\| A...	2.0E-48	[21..272]	[32..274]
YF22_SCHPO - Uncharacterized TLC domain-containing protein C17A2.02c OS=Schizosaccharomyces pombe (strain 972 / A... SPAC17A2.02c - DUF887 family protein	5.0E-45	[32..276]	[39..276]
gi\|113534153, gi... - gi\|34909246\|ref\|NP_915970.1\| B1148D12.11 [Oryza sativa (japonica cultivar-group)], gi\|15528785\|dbj\|B...	5.0E-44	[31..272]	[16..249]

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Predicted Domain #1

Region A:
Residues: [1-279]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNANSTTTAI GLTSPFEKLS FFPHSSNLIL AHLHEIIFSF VFYQLAFSVV APFLNKVVFR  60
   61 KHYTTIRDPL LKIDFNVHTV SMIQAVVSNT VLLPTLTTPM HYNVVTYTDS YSSMVSSLSA 120
  121 GYFIWDLTMC VRYFKLYGLE FTGHAIGSVY VMLLSLRPFC QPWIGRFLIY EASTPFVNIN 180
  181 WFIMQCNAKS KNSIPLWFNV VNGLLLMTVF FVVRICWGSI ASALLFRQMW KVRDELPKFS 240
  241 AVTMMSLNIF MNLLNVLWFK KMIRIAKKLA KPAPTSKLD

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [66-279]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IRDPLLKIDF NVHTVSMIQA VVSNTVLLPT LTTPMHYNVV TYTDSYSSMV SSLSAGYFIW  60
   61 DLTMCVRYFK LYGLEFTGHA IGSVYVMLLS LRPFCQPWIG RFLIYEASTP FVNINWFIMQ 120
  121 CNAKSKNSIP LWFNVVNGLL LMTVFFVVRI CWGSIASALL FRQMWKVRDE LPKFSAVTMM 180
  181 SLNIFMNLLN VLWFKKMIRI AKKLAKPAPT SKLD

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits