YRC Public Data Repository - Protein Structure Prediction

Protein:	NPA3
Organism:	Saccharomyces cerevisiae
Length:	385 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NPA3.

Description	E-value	Query Range	Subject Range
gi\|151945139 - gi\|151945139\|gb\|EDN63390.1\| nucleolar preribosomal associated protein [Saccharomyces cerevisiae YJM7... NPA3 - Essential, conserved, cytoplasmic ATPase; phosphorylated by the Pcl1p-Pho85p kinase complex GPN1_YEAST - GPN-loop GTPase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NPA3 PE=1 SV=1	2.0E-80	[1..385]	[1..385]
SPBC119.15 - AAA family ATPase, unknown biological role GPN1_SCHPO - GPN-loop GTPase 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC119.15 PE=1 SV=1	1.0E-60	[6..366]	[11..367]
gi\|11275267 - pir\|\|F81215 signal recognition particle protein NMB0295 [imported] - Neisseria meningitidis (strain ... gi\|15676217, gi\|... - gi\|7225519\|gb\|AAF40746.1\| signal recognition particle protein [Neisseria meningitidis MC58], gi\|1567...	3.0E-58	[5..384]	[102..447]
gi\|1800015 - dbj\|BAA16495.1\| SIGNAL RECOGNITION PARTICLE PROTEIN (FIFTY-FOUR HOMOLOG) (P48). [Escherichia coli]	3.0E-57	[5..360]	[22..345]
gi\|226513615, gi... - gi\|254494575\|ref\|ZP_05107746.1\| signal recognition particle protein [Neisseria gonorrhoeae 1291], gi... gi\|240113818 - gi\|240113818\|ref\|ZP_04728308.1\| putative signal recognition particle protein [Neisseria gonorrhoeae ... gi\|240014949 - gi\|240014949\|ref\|ZP_04721862.1\| putative signal recognition particle protein [Neisseria gonorrhoeae ... gi\|19568856 - gi\|19568856\|gb\|AAL91941.1\|AF482013_1 signal recognition particle signal sequence binding protein Ffh... gi\|240126527 - gi\|240126527\|ref\|ZP_04739413.1\| putative signal recognition particle protein [Neisseria gonorrhoeae ... gi\|240124316 - gi\|240124316\|ref\|ZP_04737272.1\| putative signal recognition particle protein [Neisseria gonorrhoeae ... gi\|194099592, gi... - gi\|194099592\|ref\|YP_002002723.1\| Signal recognition particle signal sequence binding protein Ffh [Ne... gi\|240122018 - gi\|240122018\|ref\|ZP_04734980.1\| putative signal recognition particle protein [Neisseria gonorrhoeae ... gi\|240116552 - gi\|240116552\|ref\|ZP_04730614.1\| putative signal recognition particle protein [Neisseria gonorrhoeae ...	5.0E-57	[5..384]	[102..447]
gi\|15603048, gi\|... - gi\|15603048\|ref\|NP_246120.1\| hypothetical protein PM1183 [Pasteurella multocida subsp. multocida str...	1.0E-56	[5..377]	[102..437]
gi\|189367273, gi... - gi\|189367273\|gb\|EDU85689.1\| signal recognition particle protein [Escherichia coli O157:H7 str. EC450... gi\|189362137, gi... - gi\|189362137\|gb\|EDU80556.1\| signal recognition particle protein [Escherichia coli O157:H7 str. EC448... gi\|187770557, gi... - gi\|187770557\|gb\|EDU34401.1\| signal recognition particle protein [Escherichia coli O157:H7 str. EC419... gi\|189003543, gi... - gi\|189003543\|gb\|EDU72529.1\| signal recognition particle protein [Escherichia coli O157:H7 str. EC407... gi\|189370881, gi... - gi\|189370881\|gb\|EDU89297.1\| signal recognition particle protein [Escherichia coli O157:H7 str. EC869... gi\|168801727, gi... - gi\|189376173\|gb\|EDU94589.1\| signal recognition particle protein [Escherichia coli O157:H7 str. EC508... gi\|169754041, gi... - gi\|170019113\|ref\|YP_001724067.1\| signal recognition particle protein [Escherichia coli ATCC 8739], g... gi\|218355412, gi... - gi\|218547871\|ref\|YP_002381662.1\| signal recognition particle protein [Escherichia fergusonii ATCC 35... gi\|218366299, gi... - gi\|218559530\|ref\|YP_002392443.1\| signal recognition particle protein [Escherichia coli S88], gi\|2183... gi\|218690728, gi... - gi\|218690728\|ref\|YP_002398940.1\| signal recognition particle protein [Escherichia coli ED1a], gi\|218... gi\|218696234, gi... - gi\|218696234\|ref\|YP_002403901.1\| signal recognition particle protein [Escherichia coli 55989], gi\|21... gi\|254794556, gi... - gi\|254794556\|ref\|YP_003079393.1\| Signal Recognition Particle (SRP) component with 4.5S RNA (ffs) [Es... gi\|218706111, gi... - gi\|218706111\|ref\|YP_002413630.1\| signal recognition particle protein [Escherichia coli UMN026], gi\|2... gi\|254162580, gi... - gi\|254162580\|ref\|YP_003045688.1\| Signal Recognition Particle (SRP) component with 4.5S RNA (ffs) [Es... gi\|226839310, gi... - gi\|254037686\|ref\|ZP_04871744.1\| signal recognition particle protein [Escherichia sp. 1_1_43], gi\|226... gi\|253323540, gi... - gi\|254289341\|ref\|YP_003055089.1\| Signal Recognition Particle (SRP) component with 4.5S RNA (ffs) [Es... gi\|251785932, gi... - gi\|251785932\|ref\|YP_003000236.1\| hypothetical protein B21_02463 [Escherichia coli BL21], gi\|24237820... gi\|170082214, gi... - gi\|170082214\|ref\|YP_001731534.1\| Signal recognition particle (SRP) component with 4.5S RNA (ffs) [Es... gi\|238901770, gi... - gi\|238901770\|ref\|YP_002927566.1\| Signal Recognition Particle (SRP) component with 4.5S RNA (ffs) [Es... gi\|208806160, gi... - gi\|208806160\|ref\|ZP_03248497.1\| signal recognition particle protein [Escherichia coli O157:H7 str. E... gi\|226899842, gi... - gi\|237706802\|ref\|ZP_04537283.1\| signal recognition particle protein [Escherichia sp. 3_2_53FAA], gi\|... EG10300 - Signal Recognition Particle (SRP) component with 4.5S RNA (ffs) / Signal Recognition Particle (SRP) ... gi\|208735091, gi... - gi\|208813814\|ref\|ZP_03255143.1\| signal recognition particle protein [Escherichia coli O157:H7 str. E... gi\|227888176, gi... - gi\|227888176\|ref\|ZP_04005981.1\| signal recognition particle protein [Escherichia coli 83972], gi\|227... gi\|208819384, gi... - gi\|208819384\|ref\|ZP_03259704.1\| signal recognition particle protein [Escherichia coli O157:H7 str. E... gi\|209398002, gi... - gi\|209398002\|ref\|YP_002272081.1\| signal recognition particle protein [Escherichia coli O157:H7 str. ... gi\|209913344, gi... - gi\|209920085\|ref\|YP_002294169.1\| signal recognition particle protein [Escherichia coli SE11], gi\|209... gi\|215266032, gi... - gi\|215487960\|ref\|YP_002330391.1\| signal recognition particle protein [Escherichia coli O127:H6 str. ... gi\|217327115, gi... - gi\|217327115\|ref\|ZP_03443198.1\| signal recognition particle protein [Escherichia coli O157:H7 str. T... SRP54_ECOLI, SR5... - Signal recognition particle protein (Fifty-four homolog) (p48) - Escherichia coli, (P07019) Signal r... SRP54_ECOL6 - Signal recognition particle protein OS=Escherichia coli O6 GN=ffh PE=3 SV=1 gi\|115513956, gi... - gi\|117624832\|ref\|YP_853745.1\| signal recognition particle protein [Escherichia coli APEC O1], gi\|115... gi\|124500901, gi... - gi\|124528009\|ref\|ZP_01699362.1\| signal recognition particle protein [Escherichia coli B], gi\|1245009... gi\|91211944, gi\|... - gi\|91211944\|ref\|YP_541930.1\| signal recognition particle protein [Escherichia coli UTI89], gi\|910735... gi\|15832727, gi\|... - gi\|15832727\|ref\|NP_311500.1\| signal recognition particle protein [Escherichia coli O157:H7 str. Saka... gi\|110344363, gi... - gi\|110642771\|ref\|YP_670501.1\| signal recognition particle protein [Escherichia coli 536], gi\|1103443... gi\|191169064, gi... - gi\|75227659\|ref\|ZP_00714400.1\| COG0541: Signal recognition particle GTPase [Escherichia coli B7A], g... gi\|75258029, gi\|... - gi\|75258029\|ref\|ZP_00729503.1\| COG0541: Signal recognition particle GTPase [Escherichia coli E22], g... gi\|75196624, gi\|... - gi\|75196624\|ref\|ZP_00706694.1\| COG0541: Signal recognition particle GTPase [Escherichia coli HS], gi... gi\|75208556, gi\|... - gi\|75208556\|ref\|ZP_00708869.1\| COG0541: Signal recognition particle GTPase [Escherichia coli B171], ... gi\|82545154, gi\|... - gi\|82545154\|ref\|YP_409101.1\| signal recognition particle protein [Shigella boydii Sb227], gi\|8124656... gi\|85675481, gi\|... - gi\|89109411\|ref\|AP_003191.1\| Signal Recognition Particle (SRP) component with 4.5S RNA (ffs) [Escher... gi\|188489634, gi... - gi\|75513216\|ref\|ZP_00735658.1\| COG0541: Signal recognition particle GTPase [Escherichia coli 53638],... gi\|73856677, gi\|... - gi\|74313200\|ref\|YP_311619.1\| signal recognition particle protein [Shigella sonnei Ss046], gi\|7385667... SRP54_ECOL6 - Signal recognition particle protein OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) G... EG10300 - Signal Recognition Particle (SRP) component with 4.5S RNA (ffs) / Signal Recognition Particle (SRP) ... SRP54_ECO57 - Signal recognition particle protein OS=Escherichia coli O157:H7 GN=ffh PE=3 SV=1 gi\|187730941, gi... - gi\|75178222\|ref\|ZP_00698281.1\| COG0541: Signal recognition particle GTPase [Shigella boydii BS512], ... gi\|12517035, gi\|... - gi\|15803132\|ref\|NP_289163.1\| signal recognition particle protein [Escherichia coli O157:H7 EDL933], ... gi\|157081263, gi... - gi\|75187357\|ref\|ZP_00700624.1\| COG0541: Signal recognition particle GTPase [Escherichia coli E24377A... gi\|83585222, gi\|... - gi\|83585222\|ref\|ZP_00923871.1\| COG0541: Signal recognition particle GTPase [Escherichia coli 101-1],...	4.0E-56	[5..360]	[102..425]
gi\|15644313, gi\|... - gi\|4982134\|gb\|AAD36632.1\|AE001802_1 signal recognition particle protein [Thermotoga maritima MSB8], ... gi\|7440083 - pir\|\|F72236 signal recognition particle protein - Thermotoga maritima (strain MSB8) gi\|170289017, gi... - gi\|170289017\|ref\|YP_001739255.1\| signal recognition particle protein [Thermotoga sp. RQ2], gi\|170176...	5.0E-56	[6..369]	[102..424]
gi\|11275266 - pir\|\|B81792 signal recognition particle protein NMA2190 [imported] - Neisseria meningitidis (strain ... gi\|7380810, gi\|2... - gi\|7380810\|emb\|CAB85402.1\| signal recognition particle protein [Neisseria meningitidis Z2491], gi\|21...	6.0E-56	[5..384]	[102..447]
gi\|6900424 - gi\|6900424\|emb\|CAB72034.1\| signal recognition particle protein [Neisseria meningitidis]	6.0E-56	[5..384]	[102..447]

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Predicted Domain #1

Region A:
Residues: [1-270]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLSTIICIG MAGSGKTTFM QRLNSHLRAE KTPPYVINLD PAVLRVPYGA NIDIRDSIKY  60
   61 KKVMENYQLG PNGAIVTSLN LFSTKIDQVI RLVEQKKDKF QNCIIDTPGQ IECFVWSASG 120
  121 AIITESFASS FPTVIAYIVD TPRNSSPTTF MSNMLYACSI LYKTKLPMIV VFNKTDVCKA 180
  181 DFAKEWMTDF ESFQAAIKED QDLNGDNGLG SGYMSSLVNS MSLMLEEFYS QLDVVGVSSF 240
  241 TGDGFDEFMQ CVDKKVDEYD QYYKQEREKA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	54.09691
Match:	2ffhA_
Description:	Signal sequence recognition protein Ffh; Signal sequence binding protein Ffh; GTPase domain of the signal sequence recognition protein Ffh
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [271-385]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNLKKKKEEM RKQKSLNGLM KDLGLNEKSS AAASDNDSID AISDLEEDAN DGLVDRDEDE  60
   61 GVEREYTFPG EERTKGEVNE NSAPDLQRRY QEAMQQVGKT ASSETAENIA KYIRN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	54.09691
Match:	2ffhA_
Description:	Signal sequence recognition protein Ffh; Signal sequence binding protein Ffh; GTPase domain of the signal sequence recognition protein Ffh
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits