YRC Public Data Repository - Protein Structure Prediction

Protein:	LIA1
Organism:	Saccharomyces cerevisiae
Length:	325 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LIA1.

Description	E-value	Query Range	Subject Range
LIA1 - Deoxyhypusine hydroxylase, a HEAT-repeat containing metalloenzyme that catalyzes hypusine formation;... gi\|190409545 - gi\|190409545\|gb\|EDV12810.1\| hypothetical protein SCRG_03722 [Saccharomyces cerevisiae RM11-1a] DOHH_YEAST - Deoxyhypusine hydroxylase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LIA1 PE=1 SV=1 gi\|151945138 - gi\|151945138\|gb\|EDN63389.1\| ligand of eif5a [Saccharomyces cerevisiae YJM789]	1.0E-55	[1..325]	[1..325]
gi\|17229395, gi\|... - gi\|17229395\|ref\|NP_485943.1\| hypothetical protein alr1903 [Nostoc sp. PCC 7120], gi\|17130993\|dbj\|BAB... gi\|25535206 - pir\|\|AI2043 hypothetical protein alr1903 [imported] - Nostoc sp. (strain PCC 7120)	2.0E-54	[4..316]	[844..1149]
IMPA4_ARATH - Importin subunit alpha-4 OS=Arabidopsis thaliana GN=IMPA4 PE=1 SV=1	2.0E-53	[25..324]	[84..418]
DOHH_SCHPO - Deoxyhypusine hydroxylase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=lia1 PE=3 SV=1 mmd1 - deoxyhypusine hydroxylase	1.0E-52	[9..322]	[2..312]
gi\|109001083 - gi\|109001083\|ref\|XP_001102387.1\| PREDICTED: karyopherin alpha 6 isoform 7 [Macaca mulatta] gi\|114555289 - gi\|114555289\|ref\|XP_513276.2\| PREDICTED: karyopherin alpha 6 isoform 2 [Pan troglodytes] gi\|123981368, gi... - gi\|61360043\|gb\|AAX41803.1\| karyopherin alpha 6 [synthetic construct], gi\|61360037\|gb\|AAX41802.1\| kar... IMA7_PONAB - Importin subunit alpha-7 OS=Pongo abelii GN=KPNA6 PE=2 SV=1 KPNA6 - karyopherin alpha 6 (importin alpha 7) gi\|55728015 - gi\|55728015\|emb\|CAH90760.1\| hypothetical protein [Pongo abelii]	5.0E-52	[1..317]	[62..412]

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Predicted Domain #1

Region A:
Residues: [1-142]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTNFEKHFQ ENVDECTLEQ LRDILVNKSG KTVLANRFRA LFNLKTVAEE FATKPEEAKK  60
   61 AIEYIAESFV NDKSELLKHE VAYVLGQTKN LDAAPTLRHV MLDQNQEPMV RHEAAEALGA 120
  121 LGDKDSLDDL NKAAKEDPHV AV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	40.69897
Match:	1b3uA_
Description:	Constant regulatory domain of protein phosphatase 2a, pr65alpha
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [143-325]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RETCELAINR INWTHGGAKD KENLQQSLYS SIDPAPPLPL EKDATIPELQ ALLNDPKQPL  60
   61 FQRYRAMFRL RDIGTDEAIL ALATGFSAES SLFKHEIAYV FGQIGSPAAV PSLIEVLGRK 120
  121 EEAPMVRHEA AEALGAIASP EVVDVLKSYL NDEVDVVRES CIVALDMYDY ENSNELEYAP 180
  181 TAN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	40.69897
Match:	1b3uA_
Description:	Constant regulatory domain of protein phosphatase 2a, pr65alpha
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits