YRC Public Data Repository - Protein Structure Prediction

Protein:	NUC1
Organism:	Saccharomyces cerevisiae
Length:	329 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NUC1.

Description	E-value	Query Range	Subject Range
NUC1 - Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has roles in mi... NUC1_YEAST - Mitochondrial nuclease OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NUC1 PE=1 SV=1	0.0	[1..329]	[1..329]
gi\|19115510 - gi\|19115510\|ref\|NP_594598.1\| hypothetical protein SPAC17C9.08 [Schizosaccharomyces pombe 972h-] pnu1 - endodeoxyribonuclease Pnu1	2.0E-94	[1..325]	[1..326]
pnu1 - endodeoxyribonuclease Pnu1 PNU1_SCHPO - Nuclease 1, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=pnu1 PE=2 SV=2	4.0E-92	[1..319]	[1..320]
gi\|14485242 - gi\|14485242\|gb\|AAK62983.1\|AF384668_1 DNA/RNA non-specific nuclease [Coccidioides immitis]	3.0E-82	[9..325]	[10..335]
NUC1_SYNRA - Nuclease OS=Syncephalastrum racemosum PE=1 SV=1	6.0E-75	[44..303]	[60..319]
gi\|6650560 - gi\|6650560\|gb\|AAF21905.1\|AF109676_1 minor nuclease C1B isoform precursor [Cunninghamella echinulata ...	4.0E-72	[42..303]	[1..251]
CE27841 - status:Confirmed UniProt:O01975 protein_id:AAK68240.1	2.0E-71	[7..298]	[450..743]
ENDOGL1 - endonuclease G-like 1	1.0E-70	[7..304]	[21..302]

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Predicted Domain #1

Region A:
Residues: [1-329]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCSRILLSGL VGLGAGTGLT YLLLNKHSPT QIIETPYPPT QKPNSNIQSH SFNVDPSGFF  60
   61 KYGFPGPIHD LQNREEFISC YNRQTQNPYW VLEHITPESL AARNADRKNS FFKEDEVIPE 120
  121 KFRGKLRDYF RSGYDRGHQA PAADAKFSQQ AMDDTFYLSN MCPQVGEGFN RDYWAHLEYF 180
  181 CRGLTKKYKS VRIVTGPLYL PKKDPIDNKF RVNYEVIGNP PSIAVPTHFF KLIVAEAPTA 240
  241 NPAREDIAVA AFVLPNEPIS NETKLTDFEV PIDALERSTG LELLQKVPPS KKKALCKEVN 300
  301 CQIVVRDFSN AAIKQSKDVK LLPPPKKRN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	126.09691
Match:	1qaeA_
Description:	Sm endonuclease
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits