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View Structure Prediction Details

Protein: PRP21
Organism: Saccharomyces cerevisiae
Length: 280 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRP21.

Description E-value Query
Range
Subject
Range
gi|4530 - gi|4530|emb|CAA47860.1| SPP91 [Saccharomyces cerevisiae]
4.0E-83 [1..280] [1..280]
prp-21 - splicing factor status:Confirmed UniProt:Q10577 protein_id:AAC78179.1
7.0E-68 [4..255] [30..304]
gi|7527720, gi|2... - gi|7527720|gb|AAF63169.1|AC010657_5 T5E21.13 [Arabidopsis thaliana], pir||G86280 protein T5E21.13 [i...
1.0E-66 [4..271] [1055..1358]
gi|42542481, gi|... - gi|42542481|gb|AAH66392.1| Sf3a1 protein [Danio rerio], gi|41056131|ref|NP_956388.1| splicing factor...
1.0E-66 [4..234] [36..299]
HGNC:10765|MIM:6... - factor 3a, subunit 1, 120kDa
SF3A1 - splicing factor 3a, subunit 1, 120kDa
gi|123984535, gi... - gi|208965566|dbj|BAG72797.1| splicing factor 3a, subunit 1 [synthetic construct], gi|123998511|gb|AB...
2.0E-66 [4..234] [45..313]
gi|11602721 - gi|11602721|emb|CAC18547.1| spliceosome-associated-protein 114 [Echinococcus multilocularis]
6.0E-66 [4..235] [20..282]
gi|10952738 - gi|10952738|gb|AAG25055.1|AF272028_1 putative RNA splicing factor [Candida albicans]
9.0E-63 [14..280] [8..326]

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Predicted Domain #1
Region A:
Residues: [1-75]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPEDTQLKE DIKTTVNYIK QHGVEFENKL LEDERFSFIK KDDPLHEYYT KLMNEPTDTV  60
   61 SGEDNDRKSE REIAR

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 13.920819
Match: PF01805
Description: Surp module

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [76-208]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPDFLFSQYD TGISRRDMEV IKLTARYYAK DKSIVEQMIS KDGEARLNFM NSSHPLHKTF  60
   61 TDFVAQYKRV YSFTGQEIKK SKRTILDNCF ERTQYWEFEK DKDREHDKLV ELCKIQFAAI 120
  121 PWDKFTQVAK FSI

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 14.468521
Match: PF01805
Description: Surp module

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [209-280]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PEDTEIFEGS LDLEQMRLRR VQTGIKLFDS IKPTNEEEKI VSDQGKQKGG DSKGKKRKIR  60
   61 AVGETRLKKS KK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.256 a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.295 a.60.4 DNA repair protein Rad51, N-terminal domain
View Download 0.240 a.70.1 N-terminal domain of the delta subunit of the F1F0-ATP synthase
View Download 0.221 a.159.1 Protein serine/threonine phosphatase 2C, C-terminal domain
View Download 0.234 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.216 d.26.1 FKBP-like
View Download 0.208 a.35.1 lambda repressor-like DNA-binding domains


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle