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View Structure Prediction Details

Protein: ERG20
Organism: Saccharomyces cerevisiae
Length: 352 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ERG20.

Description E-value Query
Range
Subject
Range
gi|168269804, gi... - gi|168269804|dbj|BAG10029.1| farnesyl pyrophosphate synthetase [synthetic construct], gi|123998535|g...
FDPS - farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, ger...
gi|114560081, gi... - gi|114560089|ref|XP_001160292.1| PREDICTED: farnesyl diphosphate synthase isoform 8 [Pan troglodytes...
6.0E-98 [7..352] [78..419]
gi|149048093, gi... - gi|37590777|gb|AAH59125.1| Farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethy...
2.0E-95 [6..352] [11..353]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
6.0E-95 [7..352] [12..353]
FPPS_BOVIN - Farnesyl pyrophosphate synthase OS=Bos taurus GN=FDPS PE=1 SV=1
5.0E-94 [7..352] [12..353]
FPPS1_ARATH - Farnesyl pyrophosphate synthase 1, mitochondrial OS=Arabidopsis thaliana GN=FPS1 PE=2 SV=2
6.0E-94 [9..352] [47..384]

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Predicted Domain #1
Region A:
Residues: [1-168]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASEKEIRRE RFLNVFPKLV EELNASLLAY GMPKEACDWY AHSLNYNTPG GKLNRGLSVV  60
   61 DTYAILSNKT VEQLGQEEYE KVAILGWCIE LLQAYFLVAD DMMDKSITRR GQPCWYKVPE 120
  121 VGEIAINDAF MLEAAIYKLL KSHFRNEKYY IDITELFHEV TFQTELGQ

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [199-218]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AYYSFYLPVA LAMYVAGITD 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 976.0103
Match: 1fps__
Description: Farnesyl diphosphate synthase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [169-191]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LMDLITAPED KVDLSKFSLK KHS

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [238-314]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IQDDYLDCFG TPEQIGKIGT DIQDNKCSWV INKALELASA EQRKTLDENY GKKDSVAEAK  60
   61 CKKIFNDLKI EQLYHEY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 976.0103
Match: 1fps__
Description: Farnesyl diphosphate synthase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [192-198]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FIVTFKT

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [219-237]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKDLKQARDV LIPLGEYFQ

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [315-352]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EESIAKDLKA KISQVDESRG FKADVLTAFL NKVYKRSK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 976.0103
Match: 1fps__
Description: Farnesyl diphosphate synthase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle