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View Structure Prediction Details

Protein: YJL132W
Organism: Saccharomyces cerevisiae
Length: 750 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YJL132W.

Description E-value Query
Range
Subject
Range
YJL132W - Putative protein of unknown function; localizes to the membrane fraction; possible Zap1p-regulated t...
YJN2_YEAST - Uncharacterized protein YJL132W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YJL132W ...
0.0 [1..750] [1..750]
gi|388765, gi|25... - gi|388765|gb|AAA36445.1| phospholipase D, gi|2507095|sp|P80108|PHLD1_HUMAN Phosphatidylinositol-glyc...
0.0 [1..267] [1..254]
PHLD_BOVIN - Phosphatidylinositol-glycan-specific phospholipase D OS=Bos taurus GN=GPLD1 PE=1 SV=1
0.0 [1..267] [1..254]
gi|111378397, gi... - gi|56800201|emb|CAI35078.1| glycosylphosphatidylinositol specific phospholipase D1 [Mus musculus], g...
0.0 [1..267] [1..254]

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Predicted Domain #1
Region A:
Residues: [1-301]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIISSWLLV SIICLTTSIV TKLQAAGVTT HLFYLTRGAP LSLKENYYPW LKAGSFFPDA  60
   61 LYSCAPSNKD WSDFAEFTHW PNFLMIAVSY WQQKYGQNDR LRGTHGSLAL KSFLIGVFTH 120
  121 QIVDVSWHSL VTDYRMHGLL RVLSETEFDG DIETAHTFLD VMGEFLTLNN VIRDSNNNEN 180
  181 WDFLTRSDWK LPREEDLMEI IRNAGLSKEK LSYAELEFCV KRGMAAAISE GYLFRSQRNQ 240
  241 LLTNIYSTSP RANDLILNHW LGGQSNLVAM LQRCVPFFET LFHDENTNEA QAEELRLCAN 300
  301 L

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [302-750]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPVSQKRINA RPLVSSLKAR KGNSHIVVSP MKSFSDFGTS LTMGKFREDN KDYLAVSAPL  60
   61 EDTVGAIYIV PWDILTVARK EDFSILQPIT AMYGSKVGTY KASDVDYLLV SQPGTCTIDF 120
  121 YFKGVKILTI KDETTEEAHQ LQFAVTGNFY DDKIPDLVVS SPSYGANETG IATFIPGSSI 180
  181 ISYLTNSDKY QVVDISTFKG VINLDGYPMK IPFQHFGATI QISDTTDKQK LIYITCQSLG 240
  241 TVFVYSSNDL HDLSIPIYYI TKNGVIPAKD SDHVEWHIIP SKEHGMFGAA IYSWNFEGMS 300
  301 FVAVSQPMFD TVFIYIEKSG QIEFFLKLVL KIKTKSDSIP DEFGSSLLFN DEEKKLYVSS 360
  361 PGSFDARGSI WKISMDELLK AGNDPKRKTL LINNLRHLML INPDKSSKGV SNFGNSMILG 420
  421 PQNHLIVGIP QYGYGNFDHM QLTGRILVL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [263-750]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GQSNLVAMLQ RCVPFFETLF HDENTNEAQA EELRLCANLP PVSQKRINAR PLVSSLKARK  60
   61 GNSHIVVSPM KSFSDFGTSL TMGKFREDNK DYLAVSAPLE DTVGAIYIVP WDILTVARKE 120
  121 DFSILQPITA MYGSKVGTYK ASDVDYLLVS QPGTCTIDFY FKGVKILTIK DETTEEAHQL 180
  181 QFAVTGNFYD DKIPDLVVSS PSYGANETGI ATFIPGSSII SYLTNSDKYQ VVDISTFKGV 240
  241 INLDGYPMKI PFQHFGATIQ ISDTTDKQKL IYITCQSLGT VFVYSSNDLH DLSIPIYYIT 300
  301 KNGVIPAKDS DHVEWHIIPS KEHGMFGAAI YSWNFEGMSF VAVSQPMFDT VFIYIEKSGQ 360
  361 IEFFLKLVLK IKTKSDSIPD EFGSSLLFND EEKKLYVSSP GSFDARGSIW KISMDELLKA 420
  421 GNDPKRKTLL INNLRHLMLI NPDKSSKGVS NFGNSMILGP QNHLIVGIPQ YGYGNFDHMQ 480
  481 LTGRILVL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.0
Match: 1txvA
Description: Structural basis for allostery in integrins and binding of ligand-mimetic therapeutics to the platelet receptor for fibrinogen
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.904790270725195 bayes_pls_golite062009
protein binding 0.53464217876859 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle