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View Structure Prediction Details

Protein: KHA1
Organism: Saccharomyces cerevisiae
Length: 873 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KHA1.

Description E-value Query
Range
Subject
Range
KHA1_YEAST - K(+)/H(+) antiporter 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KHA1 PE=1 SV=1
KHA1 - Putative K+/H+ antiporter with a probable role in intracellular cation homeostasis, localized to Gol...
0.0 [1..873] [1..873]
CHX17_ARATH - Cation/H(+) antiporter 17 OS=Arabidopsis thaliana GN=CHX17 PE=1 SV=1
0.0 [1..655] [12..639]
gi|113534154, gi... - gi|56785331|dbj|BAD82290.1| Na+/H+ antiporter-like protein [Oryza sativa Japonica Group], gi|1512839...
0.0 [1..625] [39..638]

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Predicted Domain #1
Region A:
Residues: [1-451]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANTVGGILS GVNPFHYNSS SPLTLFLFQA CLILLVCNLI HIPFSMMRQP KVISEVISGV  60
   61 ILGPTIFGQI PNYTNTIFPT SSIPGLNLVA NLGIILFMFF LGLEVDIAFI KKHLKKALVI 120
  121 GIVTLAVPFG FGCLLAIPLF HTYANKTEGE RHIKFSVFMV FIAVSISVTA FPVLCRILNE 180
  181 LRLIKDRAGI VVLAAGIIND IMGWILLALS IILSSAEGSP VNTVYILLIT FAWFLIYFFP 240
  241 LKYLLRWVLI RTHELDRSKP SPLATMCILF IMFISAYFTD IIGVHPIFGA FIAGLVVPRD 300
  301 DHYVVKLTER MEDIPNIVFI PIYFAVAGLN VDLTLLNEGR DWGYVFATIG IAIFTKIISG 360
  361 TLTAKLTGLF WREATAAGVL MSCKGIVEIV VLTVGLNAGI ISRKIFGMFV LMALVSTFVT 420
  421 TPLTQLVYPD SYRDGVRKSL STPAEDDGAA D

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 16.187087
Match: PF00999
Description: Sodium/hydrogen exchanger family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [452-551]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLDSEGVDKT EINTQLNSLA DVSKYRIGEL TTVINTTEAI SPSLKLLNYL SLGVSPKPKN  60
   61 NKHKNETSLS RMTTATDSTL KSNTFKIKKM VHIWSKSVDD 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [552-656]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VDTNLSVIDE KLTPFEGVGA LRAIHLRLLT ERTTDLLQSS SLYNDDPHFT ANTDSLLQIF  60
   61 DIFSNLSKIP FSSEVIFSTM REKAANIATM KMDSTDLILL PLKGA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [657-873]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SYEYRGSPVF IDEKYANFDH IYSHLLGLNE LSSTFFKSIF QSLKANFAVQ ISNTYGRLNA  60
   61 DRFKRKRFNL LLPKPYLTQS DYLGLYLLLL ICYRDGYNND NASCSIFINS KNIDFAKDLS 120
  121 TAFAEHDWLN ESTIKIVDIP FETKVPEEAI EKPSFIETVL DVGLSDTALA DIEETTFIIG 180
  181 EDLPDESEPF SEEVRTVIFE GSNRRFDTLI VHHFSSE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle