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View Structure Prediction Details

Protein: PSF2
Organism: Saccharomyces cerevisiae
Length: 213 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PSF2.

Description E-value Query
Range
Subject
Range
gi|207344004 - gi|207344004|gb|EDZ71287.1| YJL072Cp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190409427 - gi|190409427|gb|EDV12692.1| subunit of the GINS complex [Saccharomyces cerevisiae RM11-1a]
PSF2 - Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication orig...
gi|151945255 - gi|151945255|gb|EDN63504.1| GINS complex subunit [Saccharomyces cerevisiae YJM789]
PSF2_YEAST - DNA replication complex GINS protein PSF2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) G...
6.0E-80 [1..213] [1..213]
gi|5042457 - gi|5042457|gb|AAD38294.1|AC007789_20 unknown protein [Oryza sativa Japonica Group]
3.0E-59 [6..194] [8..179]
gi|55644351 - gi|55644351|ref|XP_511151.1| PREDICTED: similar to DNA replication complex GINS protein PSF2 (HSPC03...
GINS2 - GINS complex subunit 2 (Psf2 homolog)
2.0E-56 [15..197] [5..172]
PSF2_MOUSE - DNA replication complex GINS protein PSF2 OS=Mus musculus GN=Gins2 PE=1 SV=1
2.0E-56 [15..197] [5..172]
psf2 - GINS complex subunit Psf2
PSF2_SCHPO - DNA replication complex GINS protein psf2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=...
3.0E-53 [1..195] [1..176]
gi|220948274, gi... - gi|220957452|gb|ACL91269.1| Psf2-PA [synthetic construct], gi|220948274|gb|ACL86680.1| Psf2-PA [synt...
Psf2-PA - The gene Psf2 is referred to in FlyBase by the symbol Dmel\Psf2 (CG18013, FBgn0031599). It is a prot...
4.0E-49 [13..199] [15..187]
CE17734 - status:Partially_confirmed UniProt:O62193 protein_id:CAB07195.1
3.0E-46 [14..185] [4..161]
PSF2_ENCCU - Probable DNA replication complex GINS protein PSF2 OS=Encephalitozoon cuniculi GN=ECU06_1410 PE=3 SV...
PSF2_ENCCU - Probable DNA replication complex GINS protein PSF2 OS=Encephalitozoon cuniculi (strain GB-M1) GN=ECU...
7.0E-45 [12..195] [4..168]
gi|16805258, gi|... - gi|7768290|emb|CAB11139.2| conserved Plasmodium protein, unknown function [Plasmodium falciparum 3D7...
0.003 [72..177] [356..476]

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Predicted Domain #1
Region A:
Residues: [1-115]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLPAHLQQT FSPEEIQFIV ENEPIKIFPR ITTRQKIRGD DRGTGNHTRW QLITTDDKAL  60
   61 NNMVAMRSTE VVLWIALLLK QQSKCSIVAP QWLTTKELDR KIQYEKTHPD RFSEL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
3'-5' DNA helicase activity 3.30007058745861 bayes_pls_golite062009
DNA helicase activity 2.7662250039458 bayes_pls_golite062009
binding 1.71578680186328 bayes_pls_golite062009
transcription regulator activity 1.2336233528067 bayes_pls_golite062009
helicase activity 1.2110072302388 bayes_pls_golite062009
protein binding 0.495328779211482 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.406116199163083 bayes_pls_golite062009
transcription elongation regulator activity 0.37490315580617 bayes_pls_golite062009
pyrophosphatase activity 0.350000641617868 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.33576520693158 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.333445385039412 bayes_pls_golite062009
catalytic activity 0.161911144249814 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [116-213]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PWNWLVLARI LFNKAKDDFH DPIHELRGKI QDLREIRQIK VLKGLKYLNE SHLQLDNLSL  60
   61 LEINELRPFI TEIMDKLREI HTASLTAGTE NDEEEFNI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle