YRC Public Data Repository - Protein Structure Prediction

Protein:	YJL070C
Organism:	Saccharomyces cerevisiae
Length:	888 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YJL070C.

Description	E-value	Query Range	Subject Range
YJL070C - Putative protein of unknown function with similarity to AMP deaminases; the authentic, non-tagged pr... YJH0_YEAST - Inactive deaminase YJL070C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YJL070C PE=1 ...	0.0	[1..888]	[1..888]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[105..880]	[149..799]
gi\|16945394 - gi\|16945394\|emb\|CAB97316.2\| probable AMP deaminase [Neurospora crassa] gi\|157071801, gi... - gi\|164427578\|ref\|XP_965366.2\| AMP deaminase [Neurospora crassa OR74A], gi\|157071801\|gb\|EAA36130.2\| A...	0.0	[105..880]	[233..883]
AMPD2 - adenosine monophosphate deaminase 2 (isoform L)	0.0	[224..877]	[298..854]
gi\|2149616, gi\|1... - gi\|2149616\|gb\|AAC53348.1\| AMP deaminase isoform C [Rattus norvegicus], gi\|13928736\|ref\|NP_113732.1\| ...	0.0	[221..879]	[230..789]
AMPD2_MOUSE - AMP deaminase 2 OS=Mus musculus GN=Ampd2 PE=1 SV=1	0.0	[224..877]	[218..774]

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Predicted Domain #1

Region A:
Residues: [1-426]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQAVERRPSL LFDEYQNSVT KPNETKNKEA RVLSENDGDV SPSVLKQKEI SVDDMDMISL  60
   61 PTEFDRQMVL GSPMFFDLED EENKIDPLPS VSHHYGNGES DSFVSSYTPS NLKTGEETKD 120
  121 LFINPFELVS QMRKRYIAAS KQDGISNIKN DTEKWFLYPK PLPKFWRFED DKRFQDPSDS 180
  181 DLNDDGDSTG TGAATPHRHG YYYPSYFTDH YYYYTKSGLK GKGNIKVPYT GEYFDLEDYK 240
  241 KQYIYHLSNQ ENTQNPLSPY SSKEESLEEE FLTDVPTFQE FRDDFAYIIE LIQSHKFNEV 300
  301 SRKRLSYLLD KFELFQYLNS KKEILANKNV PYRDFYNSRK VDRDLSLSGC ISQRQLSEYI 360
  361 WEKINLEPER IVYQDPETSR KLSLRDIFQF GCSSNDQPIA IGLKLIDDEF LDWYRNIYLI 420
  421 DYHLTP

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [427-888]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKVAKLVGKE MRFYLLAKVF LEFDNFIEGE YLAEIFIKYV IHILEKSKYQ LAQVSVNFQF  60
   61 YSSGEDWYKK FSQWLLRWKL VSYNIRWNIQ IARIFPKLFK ENVVSNFQEF LDLIFNPLFT 120
  121 LEKEQLPIDS SVNTDIIGLQ FFLSNVCSMD LVIKESDEYY WKEFTDMNCK PKFWTAQGDN 180
  181 PTVAHYMYYI YKSLAKVNFL RSQNLQNTIT LRNYCSPLSS RTSQFGVDLY FTDQVESLVC 240
  241 NLLLCNGGLL QVEPLWDTAT MIQYLFYLFQ IPILAAPLSS VSLLNSQKST FLKNKNVLLE 300
  301 HDYLKDQETA KINPSRDITV GEQRSYETNP FMKMFKMGLK ISLSSKSILY NSSYTLEPLI 360
  361 EEYSVAASIY LLNPTDLCEL SRTSVLSSGY EGWYKAHWIG VGVKKAPYFE ENVGGIDNWY 420
  421 DTAKDTSIKH NVPMIRRRYR KETLDQEWNF VRDHFGVINS IW

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	14.57
Match:	1m7mA
Description:	No description for 1m7mA was found.

Predicted functions:

Term	Confidence	Notes
hydrolase activity	1.10207799789608	bayes_pls_golite062009
catalytic activity	0.935564737557247	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: