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View Structure Prediction Details

Protein: TAD2
Organism: Saccharomyces cerevisiae
Length: 250 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TAD2.

Description E-value Query
Range
Subject
Range
TAD2 - Subunit of tRNA-specific adenosine-34 deaminase, forms a heterodimer with Tad3p that converts adenos...
gi|151945050 - gi|151945050|gb|EDN63301.1| tRNA-specific adenosine deaminase subunit [Saccharomyces cerevisiae YJM7...
TAD2_YEAST - tRNA-specific adenosine deaminase subunit TAD2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S28...
1.0E-69 [1..250] [1..250]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-65 [1..237] [47..265]
RIBD_ACTPL - Riboflavin biosynthesis protein RibD OS=Actinobacillus pleuropneumoniae GN=ribD PE=3 SV=2
2.0E-65 [1..237] [13..231]
gi|238899702, gi... - gi|238899702|ref|YP_002925498.1| fused diaminohydroxyphosphoribosylaminopyrimidine deaminase and 5-a...
EG11321 - fused diaminohydroxyphosphoribosylaminopyrimidine deaminase and 5-amino-6-(5-phosphoribosylamino) ur...
gi|85674554, gi|... - gi|89107284|ref|AP_001064.1| fused diaminohydroxyphosphoribosylaminopyrimidin e deaminase and 5-amin...
EG11321 - fused diaminohydroxyphosphoribosylaminopyrimidine deaminase and 5-amino-6-(5-phosphoribosylamino) ur...
gi|170080000, gi... - gi|170080000|ref|YP_001729320.1| fused diaminohydroxyphosphoribosylaminopyrimidine deaminase and 5-a...
RIBD_ECOLI - Riboflavin biosynthesis protein ribD [Includes: Diaminohydroxyphosphoribosylaminopyrimidine deaminas...
8.0E-65 [1..236] [1..231]
gi|15900115, gi|... - gi|15900115|ref|NP_344719.1| riboflavin biosynthesis protein RibD [Streptococcus pneumoniae TIGR4], ...
gi|25331490 - pir||F95020 riboflavin biosynthesis protein RibD [imported] - Streptococcus pneumoniae (strain TIGR4...
1.0E-63 [1..247] [1..230]
gi|182683162, gi... - gi|182683162|ref|YP_001834909.1| riboflavin biosynthesis protein RibD [Streptococcus pneumoniae CGSP...
gi|183577789, gi... - gi|183577789|gb|EDT98317.1| riboflavin biosynthesis protein RibD [Streptococcus pneumoniae MLV-016],...
gi|147757179, gi... - gi|148996604|ref|ZP_01824322.1| riboflavin synthase subunit alpha [Streptococcus pneumoniae SP11-BS7...
gi|116076349, gi... - gi|116515773|ref|YP_815688.1| riboflavin biosynthesis protein RibD [Streptococcus pneumoniae D39], g...
gi|25331496 - pir||D97892 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193) [imported] - Streptococ...
gi|15902208, gi|... - gi|15902208|ref|NP_357758.1| riboflavin biosynthesis protein RibD [Streptococcus pneumoniae R6], gi|...
2.0E-63 [1..247] [1..230]
gi|18891968, gi|... - gi|18976434|ref|NP_577791.1| riboflavin-specific deaminase [Pyrococcus furiosus DSM 3638], gi|188919...
6.0E-63 [1..250] [1..228]
gi|25331470 - pir||A86749 riboflavin-specific deaminase (EC 3.5.4.-) [imported] - Lactococcus lactis subsp. lactis...
gi|15672975, gi|... - gi|15672975|ref|NP_267149.1| riboflavin-specific deaminase [Lactococcus lactis subsp. lactis Il1403]...
8.0E-62 [2..247] [3..231]
RIBD_BACSU - Riboflavin biosynthesis protein RibD OS=Bacillus subtilis GN=ribD PE=1 SV=1
gi|221323767 - gi|221323767|ref|ZP_03605061.1| riboflavin-specific deaminase [Bacillus subtilis subsp. subtilis str...
gi|34873545 - gi|34873545|gb|AAQ83285.1| RibG [Cloning vector pRFN4]
gi|221319491 - gi|221319491|ref|ZP_03600785.1| riboflavin-specific deaminase [Bacillus subtilis subsp. subtilis str...
RIBD_BACSU - Riboflavin biosynthesis protein RibD OS=Bacillus subtilis (strain 168) GN=ribD PE=1 SV=1
gi|221314569 - gi|221314569|ref|ZP_03596374.1| riboflavin-specific deaminase [Bacillus subtilis subsp. subtilis str...
1.0E-61 [4..236] [3..218]
gi|19704838, gi|... - gi|19712714|gb|AAL93632.1| Diaminohydroxyphosphoribosylaminopyrimidine deaminase [Fusobacterium nucl...
1.0E-61 [3..236] [6..227]

Back

Predicted Domain #1
Region A:
Residues: [1-142]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQHIKHMRTA VRLARYALDH DETPVACIFV HTPTGQVMAY GMNDTNKSLT GVAHAEFMGI  60
   61 DQIKAMLGSR GVVDVFKDIT LYVTVEPCIM CASALKQLDI GKVVFGCGNE RFGGNGTVLS 120
  121 VNHDTCTLVP KNNSAAGYES IP

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 12.06
Match: 1jtkA
Description: mono-domain cytidine deaminase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [143-250]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GILRKEAIML LRYFYVRQNE RAPKPRSKSD RVLDKNTFPP MEWSKYLNEE AFIETFGDDY  60
   61 RTCFANKVDL SSNSVDWDLI DSHQDNIIQE LEEQCKMFKF NVHKKSKV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle