YRC Public Data Repository - Protein Structure Prediction

Protein:	TAD2
Organism:	Saccharomyces cerevisiae
Length:	250 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TAD2.

Description	E-value	Query Range	Subject Range
TAD2 - Subunit of tRNA-specific adenosine-34 deaminase, forms a heterodimer with Tad3p that converts adenos... gi\|151945050 - gi\|151945050\|gb\|EDN63301.1\| tRNA-specific adenosine deaminase subunit [Saccharomyces cerevisiae YJM7... TAD2_YEAST - tRNA-specific adenosine deaminase subunit TAD2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S28...	1.0E-69	[1..250]	[1..250]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	1.0E-65	[1..237]	[47..265]
RIBD_ACTPL - Riboflavin biosynthesis protein RibD OS=Actinobacillus pleuropneumoniae GN=ribD PE=3 SV=2	2.0E-65	[1..237]	[13..231]
gi\|238899702, gi... - gi\|238899702\|ref\|YP_002925498.1\| fused diaminohydroxyphosphoribosylaminopyrimidine deaminase and 5-a... EG11321 - fused diaminohydroxyphosphoribosylaminopyrimidine deaminase and 5-amino-6-(5-phosphoribosylamino) ur... gi\|85674554, gi\|... - gi\|89107284\|ref\|AP_001064.1\| fused diaminohydroxyphosphoribosylaminopyrimidin e deaminase and 5-amin... EG11321 - fused diaminohydroxyphosphoribosylaminopyrimidine deaminase and 5-amino-6-(5-phosphoribosylamino) ur... gi\|170080000, gi... - gi\|170080000\|ref\|YP_001729320.1\| fused diaminohydroxyphosphoribosylaminopyrimidine deaminase and 5-a... RIBD_ECOLI - Riboflavin biosynthesis protein ribD [Includes: Diaminohydroxyphosphoribosylaminopyrimidine deaminas...	8.0E-65	[1..236]	[1..231]
gi\|15900115, gi\|... - gi\|15900115\|ref\|NP_344719.1\| riboflavin biosynthesis protein RibD [Streptococcus pneumoniae TIGR4], ... gi\|25331490 - pir\|\|F95020 riboflavin biosynthesis protein RibD [imported] - Streptococcus pneumoniae (strain TIGR4...	1.0E-63	[1..247]	[1..230]
gi\|182683162, gi... - gi\|182683162\|ref\|YP_001834909.1\| riboflavin biosynthesis protein RibD [Streptococcus pneumoniae CGSP... gi\|183577789, gi... - gi\|183577789\|gb\|EDT98317.1\| riboflavin biosynthesis protein RibD [Streptococcus pneumoniae MLV-016],... gi\|147757179, gi... - gi\|148996604\|ref\|ZP_01824322.1\| riboflavin synthase subunit alpha [Streptococcus pneumoniae SP11-BS7... gi\|116076349, gi... - gi\|116515773\|ref\|YP_815688.1\| riboflavin biosynthesis protein RibD [Streptococcus pneumoniae D39], g... gi\|25331496 - pir\|\|D97892 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193) [imported] - Streptococ... gi\|15902208, gi\|... - gi\|15902208\|ref\|NP_357758.1\| riboflavin biosynthesis protein RibD [Streptococcus pneumoniae R6], gi\|...	2.0E-63	[1..247]	[1..230]
gi\|18891968, gi\|... - gi\|18976434\|ref\|NP_577791.1\| riboflavin-specific deaminase [Pyrococcus furiosus DSM 3638], gi\|188919...	6.0E-63	[1..250]	[1..228]
gi\|25331470 - pir\|\|A86749 riboflavin-specific deaminase (EC 3.5.4.-) [imported] - Lactococcus lactis subsp. lactis... gi\|15672975, gi\|... - gi\|15672975\|ref\|NP_267149.1\| riboflavin-specific deaminase [Lactococcus lactis subsp. lactis Il1403]...	8.0E-62	[2..247]	[3..231]
RIBD_BACSU - Riboflavin biosynthesis protein RibD OS=Bacillus subtilis GN=ribD PE=1 SV=1 gi\|221323767 - gi\|221323767\|ref\|ZP_03605061.1\| riboflavin-specific deaminase [Bacillus subtilis subsp. subtilis str... gi\|34873545 - gi\|34873545\|gb\|AAQ83285.1\| RibG [Cloning vector pRFN4] gi\|221319491 - gi\|221319491\|ref\|ZP_03600785.1\| riboflavin-specific deaminase [Bacillus subtilis subsp. subtilis str... RIBD_BACSU - Riboflavin biosynthesis protein RibD OS=Bacillus subtilis (strain 168) GN=ribD PE=1 SV=1 gi\|221314569 - gi\|221314569\|ref\|ZP_03596374.1\| riboflavin-specific deaminase [Bacillus subtilis subsp. subtilis str...	1.0E-61	[4..236]	[3..218]
gi\|19704838, gi\|... - gi\|19712714\|gb\|AAL93632.1\| Diaminohydroxyphosphoribosylaminopyrimidine deaminase [Fusobacterium nucl...	1.0E-61	[3..236]	[6..227]

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Predicted Domain #1

Region A:
Residues: [1-142]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQHIKHMRTA VRLARYALDH DETPVACIFV HTPTGQVMAY GMNDTNKSLT GVAHAEFMGI  60
   61 DQIKAMLGSR GVVDVFKDIT LYVTVEPCIM CASALKQLDI GKVVFGCGNE RFGGNGTVLS 120
  121 VNHDTCTLVP KNNSAAGYES IP

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	12.06
Match:	1jtkA
Description:	mono-domain cytidine deaminase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [143-250]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GILRKEAIML LRYFYVRQNE RAPKPRSKSD RVLDKNTFPP MEWSKYLNEE AFIETFGDDY  60
   61 RTCFANKVDL SSNSVDWDLI DSHQDNIIQE LEEQCKMFKF NVHKKSKV

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits