YRC Public Data Repository - Protein Structure Prediction

Protein:	YIR042C
Organism:	Saccharomyces cerevisiae
Length:	236 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YIR042C.

Description	E-value	Query Range	Subject Range
YIR042C - Putative protein of unknown function; YIR042C is a non-essential gene YIW2_YEAST - Uncharacterized protein YIR042C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YIR042C ...	4.0E-56	[1..236]	[1..236]
gi\|149292521, gi... - gi\|149366108\|ref\|ZP_01888143.1\| putative acetyltransferase [Yersinia pestis CA88-4125], gi\|149292521... gi\|166208246, gi... - gi\|166211066\|ref\|ZP_02237101.1\| acetyltransferase, GNAT family [Yersinia pestis biovar Antiqua str. ... gi\|165991764, gi... - gi\|166009209\|ref\|ZP_02230107.1\| acetyltransferase, GNAT family [Yersinia pestis biovar Antiqua str. ... gi\|165939749, gi... - gi\|165939749\|ref\|ZP_02228291.1\| acetyltransferase, GNAT family [Yersinia pestis biovar Orientalis st... gi\|229693697, gi... - gi\|229897360\|ref\|ZP_04512516.1\| putative acetyltransferase [Yersinia pestis biovar Orientalis str. P... gi\|162353148, gi... - gi\|162420333\|ref\|YP_001606598.1\| acetyltransferase [Yersinia pestis Angola], gi\|162353148\|gb\|ABX8709... gi\|229894632, gi... - gi\|229894632\|ref\|ZP_04509813.1\| putative acetyltransferase [Yersinia pestis Pestoides A], gi\|2297023... gi\|21959210, gi\|... - gi\|22126239\|ref\|NP_669662.1\| hypothetical protein y2355 [Yersinia pestis KIM], gi\|21959210\|gb\|AAM859... gi\|25510520, gi\|... - gi\|4106591\|emb\|CAA21346.1\| yp10 [Yersinia pestis], pir\|\|AF0238 probable acetyltransferase YPO1955 [i... gi\|167466547 - gi\|167466547\|ref\|ZP_02331251.1\| acetyltransferase, GNAT family protein [Yersinia pestis FV-1] gi\|15979972, gi\|... - gi\|218929069\|ref\|YP_002346944.1\| putative acetyltransferase [Yersinia pestis CO92], gi\|16122201\|ref\|... gi\|166961816, gi... - gi\|167420121\|ref\|ZP_02311874.1\| acetyltransferase, GNAT family [Yersinia pestis biovar Orientalis st... gi\|45436374, gi\|... - gi\|45441513\|ref\|NP_993052.1\| putative acetyltransferase [Yersinia pestis biovar Microtus str. 91001]... gi\|167049451, gi... - gi\|167401062\|ref\|ZP_02306565.1\| acetyltransferase, GNAT family [Yersinia pestis biovar Antiqua str. ...	1.0E-45	[5..231]	[67..295]
gi\|15900190, gi\|... - gi\|66877108\|ref\|ZP_00402752.1\| COG1670: Acetyltransferases, including N-acetylases of ribosomal prot... gi\|25388270 - pir\|\|A95030 acetyltransferase, GNAT family [imported] - Streptococcus pneumoniae (strain TIGR4)	1.0E-44	[4..230]	[3..231]
gi\|25508126 - pir\|\|D97901 conserved hypothetical protein spr0236 [imported] - Streptococcus pneumoniae (strain R6) gi\|15902280, gi\|... - gi\|15902280\|ref\|NP_357830.1\| hypothetical protein spr0236 [Streptococcus pneumoniae R6], gi\|15457783... gi\|116076468, gi... - gi\|116515892\|ref\|YP_815757.1\| acetyltransferase, GNAT family protein [Streptococcus pneumoniae D39],...	2.0E-44	[4..230]	[3..231]
gi\|17988346, gi\|... - gi\|17988346\|ref\|NP_540979.1\| ribosomal-protein-serine acetyltransferase [Brucella melitensis 16M], g... gi\|25527000 - pir\|\|AH3509 ribosomal-protein-serine acetyltransferase (EC 2.3.1.-) [imported] - Brucella melitensis...	4.0E-44	[14..232]	[20..240]
gi\|13472629, gi\|... - gi\|14023375\|dbj\|BAB49982.1\| mll2986 [Mesorhizobium loti MAFF303099], gi\|13472629\|ref\|NP_104196.1\| hy...	1.0E-43	[12..233]	[2..225]
gi\|25524160 - pir\|\|AD3109 acetyltransferase [imported] - Agrobacterium tumefaciens (strain C58, Dupont) gi\|159141326, gi... - gi\|17938185\|ref\|NP_534974.1\| acetyltransferase [Agrobacterium tumefaciens str. C58], gi\|17742978\|gb\|...	2.0E-43	[13..236]	[2..227]
gi\|15075907 - gi\|15075907\|emb\|CAC47461.1\| Conserved hypothetical protein [Sinorhizobium meliloti 1021] gi\|15966635 - gi\|15966635\|ref\|NP_386988.1\| hypothetical protein SMc03151 [Sinorhizobium meliloti 1021]	2.0E-39	[13..235]	[2..227]
gi\|9951762, gi\|1... - gi\|9951762\|gb\|AAG08818.1\|AE004956_2 conserved hypothetical protein [Pseudomonas aeruginosa PAO1], gi... gi\|11348339 - pir\|\|D82966 conserved hypothetical protein PA5433 [imported] - Pseudomonas aeruginosa (strain PAO1)	3.0E-36	[17..232]	[6..224]

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Predicted Domain #1

Region A:
Residues: [1-236]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANLNIFGQE VGADVEGWTT RAFPEKVVLK GNTCRLEPLD RERHGSELFS AYSEAGQKLW  60
   61 TYLPAGPFTN LEEYLEFIKE LNETKDTVPF AIINKETERA VGTLCLIRID EANGSLEVGY 120
  121 VVFSPELQKT IIATEAQFLL MKYVFDDLQY RRYEWKCDSL NGPSRRAAMR LGFKYEGTFR 180
  181 QVVVYKGRTR DTQWFSIIDK EWLRIRKTFE EWLDKTNFEN GKQKRGIAAI RESLSN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	8.69897
Match:	1i12A_
Description:	Glucosamine-phoshate N-acetyltransferase GNA1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.97933499002461	bayes_pls_golite062009
transferase activity	1.72447231774431	bayes_pls_golite062009
transferase activity, transferring acyl groups	1.42711272311757	bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups	1.24328242407788	bayes_pls_golite062009
acyltransferase activity	1.2338745976101	bayes_pls_golite062009
N-acyltransferase activity	0.890897647236405	bayes_pls_golite062009
acetyltransferase activity	0.823367673029436	bayes_pls_golite062009
N-acetyltransferase activity	0.498634717186713	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: